 Sunil K Malonia PhD
| Title | Instructor |
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| Institution | University of Massachusetts Medical School |
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| Department | Molecular, Cell and Cancer Biology |
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| Address | 364 Plantation Street
University of Massachusetts Medical School
Worcester MA
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| Phone | 508-856-5330 |
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| Email |  |
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| vCard | Download vCard |
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| Institution | UMMS - School of Medicine |
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| Department | Molecular, Cell and Cancer Biology |
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 Biography | Dr. Bhimrao Ambedkar University, Agra, UP, India | BS | | Biology | | Savitribai Phule Pune University, Pune, MH, India | MS | | Biotechnology | | Savitribai Phule Pune University, Pune, MH, India | PHD | | Biotechnology |
| 2005 - 2007 | Junior Research fellowship, Indian Council of Medical Research, India | | 2007 - 2010 | Senior Research fellowship, Indian Council of Medical Research, India |
Overview My research interests are centered around understanding the cellular, biochemical, and molecular basis of human diseases-- particularly cancer and certain rare genetic disorders. The major aim of my research is to understand, how certain genetic and epigenetic events contribute to the development/ or progression of these diseases, identifying regulatory pathways and druggable targets. Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Paul D, Islam S, Manne RK, Dinesh US, Malonia SK, Maity B, Boppana R, Rapole S, Shetty P, Santra MK. F-box protein FBXO16 functions as a tumor suppressor by attenuating nuclear ß-catenin function. J Pathol. 2019 Feb 04. PMID: 30714168.
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Choppara S, Malonia SK, Sankaran G, Green MR, Santra MK. Degradation of FBXO31 by APC/C is regulated by AKT- and ATM-mediated phosphorylation. Proc Natl Acad Sci U S A. 2018 Jan 30; 115(5):998-1003. PMID: 29343641.
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Mou H, Moore J, Malonia SK, Li Y, Ozata DM, Hough S, Song CQ, Smith JL, Fischer A, Weng Z, Green MR, Xue W. Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis. Proc Natl Acad Sci U S A. 2017 Mar 20. PMID: 28320962.
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Yadav B, Malonia SK, Majumdar SS, Gupta P, Wadhwa N, Badhwar A, Gupta UD, Katoch VM, Chattopadhyay S. Constitutive expression of SMAR1 confers susceptibility to Mycobacterium tuberculosis infection in a transgenic mouse model. Indian J Med Res. 2015 Dec; 142(6):732-41. PMID: 26831422; PMCID: PMC4774070.
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Malonia SK, Dutta P, Santra MK, Green MR. F-box protein FBXO31 directs degradation of MDM2 to facilitate p53-mediated growth arrest following genotoxic stress. Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28):8632-7. PMID: 26124108.
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Chemmannur SV, Badhwar AJ, Mirlekar B, Malonia SK, Gupta M, Wadhwa N, Bopanna R, Mabalirajan U, Majumdar S, Ghosh B, Chattopadhyay S. Nuclear matrix binding protein SMAR1 regulates T-cell differentiation and allergic airway disease. Mucosal Immunol. 2015 Nov; 8(6):1201-11. PMID: 25736456; PMCID: PMC4762901.
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Malonia SK, Yadav B, Sinha S, Lazennec G, Chattopadhyay S. Chromatin remodeling protein SMAR1 regulates NF-?B dependent Interleukin-8 transcription in breast cancer. Int J Biochem Cell Biol. 2014 Oct; 55:220-6. PMID: 25239884.
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Wajapeyee N, Malonia SK, Palakurthy RK, Green MR. Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors. Genes Dev. 2013 Oct 15; 27(20):2221-6. PMID: 24105743.
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Sinha S, Malonia SK, Mittal SP, Mathai J, Pal JK, Chattopadhyay S. Chromatin remodelling protein SMAR1 inhibits p53 dependent transactivation by regulating acetyl transferase p300. Int J Biochem Cell Biol. 2012 Jan; 44(1):46-52. PMID: 22074660.
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Malonia SK, Sinha S, Lakshminarasimhan P, Singh K, Jalota-Badhwar A, Rampalli S, Kaul-Ghanekar R, Chattopadhyay S. Gene regulation by SMAR1: Role in cellular homeostasis and cancer. Biochim Biophys Acta. 2011 Jan; 1815(1):1-12. PMID: 20709157.
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Sinha S, Malonia SK, Mittal SP, Singh K, Kadreppa S, Kamat R, Mukhopadhyaya R, Pal JK, Chattopadhyay S. Coordinated regulation of p53 apoptotic targets BAX and PUMA by SMAR1 through an identical MAR element. EMBO J. 2010 Feb 17; 29(4):830-42. PMID: 20075864; PMCID: PMC2829167.
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Singh K, Sinha S, Malonia SK, Chattopadhyay S. Tumor Necrosis Factor alpha (TNFalpha) regulates CD40 expression through SMAR1 phosphorylation. Biochem Biophys Res Commun. 2010 Jan 08; 391(2):1255-61. PMID: 20006573.
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Singh K, Sinha S, Malonia SK, Bist P, Tergaonkar V, Chattopadhyay S. Tumor suppressor SMAR1 represses IkappaBalpha expression and inhibits p65 transactivation through matrix attachment regions. J Biol Chem. 2009 Jan 09; 284(2):1267-78. PMID: 18981184.
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Singh P, Wesley C, Jadaun GP, Malonia SK, Das R, Upadhyay P, Faujdar J, Sharma P, Gupta P, Mishra AK, Singh K, Chauhan DS, Sharma VD, Gupta UD, Venkatesan K, Katoch VM. Comparative evaluation of Löwenstein-Jensen proportion method, BacT/ALERT 3D system, and enzymatic pyrazinamidase assay for pyrazinamide susceptibility testing of Mycobacterium tuberculosis. J Clin Microbiol. 2007 Jan; 45(1):76-80. PMID: 17093022; PMCID: PMC1828947.
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Singh P, Mishra AK, Malonia SK, Chauhan DS, Sharma VD, Venkatesan K, Katoch VM. The paradox of pyrazinamide: an update on the molecular mechanisms of pyrazinamide resistance in Mycobacteria. J Commun Dis. 2006 Mar; 38(3):288-98. PMID: 17373362.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 2006 | 2 | | 2008 | 1 | | 2009 | 1 | | 2010 | 2 | | 2011 | 1 | | 2013 | 1 | | 2014 | 1 | | 2015 | 3 | | 2017 | 1 | | 2018 | 1 | | 2019 | 1 |
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