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Johanna Margaret Seddon MD, ScM

TitleProfessor
InstitutionUniversity of Massachusetts Medical School
DepartmentOphthalmology and Visual Sciences
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North, S
Worcester MA 01655
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentOphthalmology and Visual Sciences


    Collapse Biography 
    Collapse education and training
    University of Pittsburgh, Pittsburgh, PA, United StatesBSChemistry/Physics
    Harvard University School of Public Health, Boston, MA, United StatesMSEpidemiology
    University of Pittsburgh School of Medicine, Pittsburgh, PA, United StatesMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kleinerman RA, Tucker MA, Sigel BS, Abramson DH, Seddon JM, Morton LM. Patterns of Cause-Specific Mortality Among 2053 Survivors of Retinoblastoma, 1914-2016. J Natl Cancer Inst. 2019 Jan 30. PMID: 30698734.
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    2. Seddon JM, Rosner B. Validated Prediction Models for Macular Degeneration Progression and Predictors of Visual Acuity Loss Identify High Risk Individuals. Am J Ophthalmol. 2018 Oct 30. PMID: 30389371.
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    3. Sandhu HS, El-Baz A, Seddon JM. Progress in Automated Deep Learning for Macular Degeneration. JAMA Ophthalmol. 2018 Sep 14. PMID: 30242352.
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    4. Sarker N, Fabijan J, Emes RD, Hemmatzadeh F, Meers J, Moreton J, Owen H, Seddon JM, Simmons G, Speight N, Trott D, Woolford L, Tarlinton RE. Identification of stable reference genes for quantitative PCR in koalas. Sci Rep. 2018 Feb 20; 8(1):3364. PMID: 29463845.
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    5. Seddon JM. Macular Degeneration Epidemiology: Nature-Nurture, Lifestyle Factors, Genetic Risk, and Gene-Environment Interactions - The Weisenfeld Award Lecture. Invest Ophthalmol Vis Sci. 2017 12 01; 58(14):6513-6528. PMID: 29288272.
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    6. Layana AG, Minnella AM, Garhöfer G, Aslam T, Holz FG, Leys A, Silva R, Delcourt C, Souied E, Seddon JM. Vitamin D and Age-Related Macular Degeneration. Nutrients. 2017 Oct 13; 9(10). PMID: 29027953.
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    7. Seddon JM, Ferrara D. Rare Genetic Variants in Age-Related Macular Degeneration. JAMA Ophthalmol. 2017 Oct 01; 135(10):1045-1046. PMID: 28859197.
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    8. Merle BMJ, Silver RE, Rosner B, Seddon JM. Associations Between Vitamin D Intake and Progression to Incident Advanced Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2017 09 01; 58(11):4569-4578. PMID: 28892825.
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    9. Ferrara D, Silver RE, Louzada RN, Novais EA, Collins GK, Seddon JM. Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2017 07 01; 58(9):3519-3529. PMID: 28715590.
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    10. Yu Y, Wagner EK, Souied EH, Seitsonen S, Immonen IJ, Häppölä P, Raychaudhuri S, Daly MJ, Seddon JM. Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degeneration†. Hum Mol Genet. 2016 12 01; 25(23):5276-5285. PMID: 28011711.
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    11. McLeod DS, Bhutto I, Edwards MM, Silver RE, Seddon JM, Lutty GA. Distribution and Quantification of Choroidal Macrophages in Human Eyes With Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2016 Nov 01; 57(14):5843-5855. PMID: 27802514.
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    12. Seddon JM, McLeod DS, Bhutto IA, Villalonga MB, Silver RE, Wenick AS, Edwards MM, Lutty GA. Histopathological Insights Into Choroidal Vascular Loss in Clinically Documented Cases of Age-Related Macular Degeneration. JAMA Ophthalmol. 2016 Nov 01; 134(11):1272-1280. PMID: 27657855.
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    13. Wagner EK, Raychaudhuri S, Villalonga MB, Java A, Triebwasser MP, Daly MJ, Atkinson JP, Seddon JM. Mapping rare, deleterious mutations in Factor H: Association with early onset, drusen burden, and lower antigenic levels in familial AMD. Sci Rep. 2016 08 30; 6:31531. PMID: 27572114.
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    14. Lane M, Ferrara D, Louzada RN, Fujimoto JG, Seddon JM. Diagnosis and Follow-Up of Nonexudative Choroidal Neovascularization With Multiple Optical Coherence Tomography Angiography Devices: A Case Report. Ophthalmic Surg Lasers Imaging Retina. 2016 08 01; 47(8):778-81. PMID: 27548457.
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    15. Seddon JM, Silver RE, Rosner B. Response to AREDS supplements according to genetic factors: survival analysis approach using the eye as the unit of analysis. Br J Ophthalmol. 2016 Dec; 100(12):1731-1737. PMID: 27471039.
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    16. Kang JH, Wu J, Cho E, Ogata S, Jacques P, Taylor A, Chiu CJ, Wiggs JL, Seddon JM, Hankinson SE, Schaumberg DA, Pasquale LR. Contribution of the Nurses' Health Study to the Epidemiology of Cataract, Age-Related Macular Degeneration, and Glaucoma. Am J Public Health. 2016 Sep; 106(9):1684-9. PMID: 27459452; PMCID: PMC4981799.
    17. Merle BM, Silver RE, Rosner B, Seddon JM. Dietary folate, B vitamins, genetic susceptibility and progression to advanced nonexudative age-related macular degeneration with geographic atrophy: a prospective cohort study. Am J Clin Nutr. 2016 Apr; 103(4):1135-44. PMID: 26961928; PMCID: PMC4807698 [Available on 04/01/17].
    18. Bhutto IA, McLeod DS, Jing T, Sunness JS, Seddon JM, Lutty GA. Increased choroidal mast cells and their degranulation in age-related macular degeneration. Br J Ophthalmol. 2016 May; 100(5):720-6. PMID: 26931413; PMCID: PMC4913697.
    19. de Carlo TE, Adhi M, Salz DA, Joseph T, Waheed NK, Seddon JM, Duker JS, Reichel E. Analysis of Choroidal and Retinal Vasculature in Inherited Retinal Degenerations Using Optical Coherence Tomography Angiography. Ophthalmic Surg Lasers Imaging Retina. 2016 Feb; 47(2):120-7. PMID: 26878444.
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    20. Shah AR, Williams S, Baumal CR, Rosner B, Duker JS, Seddon JM. Predictors of Response to Intravitreal Anti-Vascular Endothelial Growth Factor Treatment of Age-Related Macular Degeneration. Am J Ophthalmol. 2016 Mar; 163:154-166.e8. PMID: 26705092.
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    21. Merle BM, Silver RE, Rosner B, Seddon JM. Adherence to a Mediterranean diet, genetic susceptibility, and progression to advanced macular degeneration: a prospective cohort study. Am J Clin Nutr. 2015 Nov; 102(5):1196-206. PMID: 26490493; PMCID: PMC4625588 [Available on 11/01/16].
    22. Triebwasser MP, Roberson ED, Yu Y, Schramm EC, Wagner EK, Raychaudhuri S, Seddon JM, Atkinson JP. Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2015 Oct; 56(11):6873-8. PMID: 26501415; PMCID: PMC4627248.
    23. Edwards MM, McLeod DS, Bhutto IA, Villalonga MB, Seddon JM, Lutty GA. Idiopathic preretinal glia in aging and age-related macular degeneration. Exp Eye Res. 2016 09; 150:44-61. PMID: 26220834.
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    24. Ferrara D, Seddon JM. Phenotypic Characterization of Complement Factor H R1210C Rare Genetic Variant in Age-Related Macular Degeneration. JAMA Ophthalmol. 2015 Jul; 133(7):785-91. PMID: 25880396.
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    25. Seddon JM, Silver RE, Kwong M, Rosner B. Risk Prediction for Progression of Macular Degeneration: 10 Common and Rare Genetic Variants, Demographic, Environmental, and Macular Covariates. Invest Ophthalmol Vis Sci. 2015 Apr; 56(4):2192-202. PMID: 25655794; PMCID: PMC4405097.
    26. Kavanagh D, Yu Y, Schramm EC, Triebwasser M, Wagner EK, Raychaudhuri S, Daly MJ, Atkinson JP, Seddon JM. Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels. Hum Mol Genet. 2015 Jul 01; 24(13):3861-70. PMID: 25788521; PMCID: PMC4459386.
    27. Sommerlad SF, Morton JM, Johnstone I, O'Leary CA, Seddon JM. Consequences of a screening programme on the prevalence of congenital hereditary sensorineural deafness in the Australian Cattle Dog. Anim Genet. 2014 Dec; 45(6):855-62. PMID: 25286978.
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    28. Wong JR, Morton LM, Tucker MA, Abramson DH, Seddon JM, Sampson JN, Kleinerman RA. Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy. J Clin Oncol. 2014 Oct 10; 32(29):3284-90. PMID: 25185089; PMCID: PMC4178525.
    29. Schramm EC, Clark SJ, Triebwasser MP, Raychaudhuri S, Seddon J, Atkinson JP. Genetic variants in the complement system predisposing to age-related macular degeneration: a review. Mol Immunol. 2014 Oct; 61(2):118-125. PMID: 25034031; PMCID: PMC4149817.
    30. Hutchinson JN, Fagerness J, Kirby A, Reynolds R, Zak A, Gimelbrant A, Plenge R, Daly M, Chess A, Seddon JM. (Epi)Genetic analyses of age-related macular degeneration: case-control and discordant twin studies. Hum Hered. 2014; 78(2):59-72. PMID: 25033836.
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    31. Hutchinson JN, Raj T, Fagerness J, Stahl E, Viloria FT, Gimelbrant A, Seddon J, Daly M, Chess A, Plenge R. Allele-specific methylation occurs at genetic variants associated with complex disease. PLoS One. 2014; 9(6):e98464. PMID: 24911414; PMCID: PMC4049588.
    32. Yu Y, Triebwasser MP, Wong EK, Schramm EC, Thomas B, Reynolds R, Mardis ER, Atkinson JP, Daly M, Raychaudhuri S, Kavanagh D, Seddon JM. Whole-exome sequencing identifies rare, functional CFH variants in families with macular degeneration. Hum Mol Genet. 2014 Oct 01; 23(19):5283-93. PMID: 24847005; PMCID: PMC4159152.
    33. Little MP, Schaeffer ML, Reulen RC, Abramson DH, Stovall M, Weathers R, de Vathaire F, Diallo I, Seddon JM, Hawkins MM, Tucker MA, Kleinerman RA. Breast cancer risk after radiotherapy for heritable and non-heritable retinoblastoma: a US-UK study. Br J Cancer. 2014 May 13; 110(10):2623-32. PMID: 24755883; PMCID: PMC4021527.
    34. Seddon JM, Reynolds R, Yu Y, Rosner B. Three new genetic loci (R1210C in CFH, variants in COL8A1 and RAD51B) are independently related to progression to advanced macular degeneration. PLoS One. 2014; 9(1):e87047. PMID: 24498017; PMCID: PMC3909074.
    35. Sobrin L, Seddon JM. Nature and nurture- genes and environment- predict onset and progression of macular degeneration. Prog Retin Eye Res. 2014 May; 40:1-15. PMID: 24374240.
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    36. Seddon JM. Genetic and environmental underpinnings to age-related ocular diseases. Invest Ophthalmol Vis Sci. 2013 Dec 13; 54(14):ORSF28-30. PMID: 24335064; PMCID: PMC3864375.
    37. Seddon JM, Yu Y, Miller EC, Reynolds R, Tan PL, Gowrisankar S, Goldstein JI, Triebwasser M, Anderson HE, Zerbib J, Kavanagh D, Souied E, Katsanis N, Daly MJ, Atkinson JP, Raychaudhuri S. Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration. Nat Genet. 2013 Nov; 45(11):1366-70. PMID: 24036952; PMCID: PMC3902040.
    38. Sobrin L, Seddon JM. Regular aspirin use and risk of age-related macular degeneration. Am J Ophthalmol. 2013 Aug; 156(2):213-217.e2. PMID: 23870358.
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    39. Seddon JM, Reynolds R, Yu Y, Rosner B. Validation of a prediction algorithm for progression to advanced macular degeneration subtypes. JAMA Ophthalmol. 2013 Apr; 131(4):448-55. PMID: 23411794.
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    40. Reynolds R, Rosner B, Seddon JM. Dietary omega-3 fatty acids, other fat intake, genetic susceptibility, and progression to incident geographic atrophy. Ophthalmology. 2013 May; 120(5):1020-8. PMID: 23481534; PMCID: PMC3758110.
    41. Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP, Buitendijk GH, Sim X, Weeks DE, Guymer RH, Merriam JE, Francis PJ, Hannum G, Agarwal A, Armbrecht AM, Audo I, Aung T, Barile GR, Benchaboune M, Bird AC, Bishop PN, Branham KE, Brooks M, Brucker AJ, Cade WH, Cain MS, Campochiaro PA, Chan CC, Cheng CY, Chew EY, Chin KA, Chowers I, Clayton DG, Cojocaru R, Conley YP, Cornes BK, Daly MJ, Dhillon B, Edwards AO, Evangelou E, Fagerness J, Ferreyra HA, Friedman JS, Geirsdottir A, George RJ, Gieger C, Gupta N, Hagstrom SA, Harding SP, Haritoglou C, Heckenlively JR, Holz FG, Hughes G, Ioannidis JP, Ishibashi T, Joseph P, Jun G, Kamatani Y, Katsanis N, N Keilhauer C, Khan JC, Kim IK, Kiyohara Y, Klein BE, Klein R, Kovach JL, Kozak I, Lee CJ, Lee KE, Lichtner P, Lotery AJ, Meitinger T, Mitchell P, Mohand-Saïd S, Moore AT, Morgan DJ, Morrison MA, Myers CE, Naj AC, Nakamura Y, Okada Y, Orlin A, Ortube MC, Othman MI, Pappas C, Park KH, Pauer GJ, Peachey NS, Poch O, Priya RR, Reynolds R, Richardson AJ, Ripp R, Rudolph G, Ryu E, Sahel JA, Schaumberg DA, Scholl HP, Schwartz SG, Scott WK, Shahid H, Sigurdsson H, Silvestri G, Sivakumaran TA, Smith RT, Sobrin L, Souied EH, Stambolian DE, Stefansson H, Sturgill-Short GM, Takahashi A, Tosakulwong N, Truitt BJ, Tsironi EE, Uitterlinden AG, van Duijn CM, Vijaya L, Vingerling JR, Vithana EN, Webster AR, Wichmann HE, Winkler TW, Wong TY, Wright AF, Zelenika D, Zhang M, Zhao L, Zhang K, Klein ML, Hageman GS, Lathrop GM, Stefansson K, Allikmets R, Baird PN, Gorin MB, Wang JJ, Klaver CC, Seddon JM, Pericak-Vance MA, Iyengar SK, Yates JR, Swaroop A, Weber BH, Kubo M, Deangelis MM, Léveillard T, Thorsteinsdottir U, Haines JL, Farrer LA, Heid IM, Abecasis GR. Seven new loci associated with age-related macular degeneration. Nat Genet. 2013 Apr; 45(4):433-9, 439e1-2. PMID: 23455636.
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    42. Ioannidis JP, Yu Y, Seddon JM. To Correct or Not to Correct-and How. Epidemiology. 2012 Nov; 23(6):912-3. PMID: 23038115.
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    43. Ioannidis JP, Yu Y, Seddon JM. Correction of phenotype misclassification based on high-discrimination genetic predictive risk models. Epidemiology. 2012 Nov; 23(6):902-9. PMID: 23023008.
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    44. Thakkinstian A, McEvoy M, Chakravarthy U, Chakrabarti S, McKay GJ, Ryu E, Silvestri G, Kaur I, Francis P, Iwata T, Akahori M, Arning A, Edwards AO, Seddon JM, Attia J. The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: a HuGE review and meta-analysis. Am J Epidemiol. 2012 Sep 01; 176(5):361-72. PMID: 22869612.
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    45. Leveziel N, Yu Y, Reynolds R, Tai A, Meng W, Caillaux V, Calvas P, Rosner B, Malecaze F, Souied EH, Seddon JM. Genetic factors for choroidal neovascularization associated with high myopia. Invest Ophthalmol Vis Sci. 2012 Jul 27; 53(8):5004-9. PMID: 22678500; PMCID: PMC3410690.
    46. Sobrin L, Ripke S, Yu Y, Fagerness J, Bhangale TR, Tan PL, Souied EH, Buitendijk GH, Merriam JE, Richardson AJ, Raychaudhuri S, Reynolds R, Chin KA, Lee AY, Leveziel N, Zack DJ, Campochiaro P, Smith RT, Barile GR, Hogg RE, Chakravarthy U, Behrens TW, Uitterlinden AG, van Duijn CM, Vingerling JR, Brantley MA, Baird PN, Klaver CC, Allikmets R, Katsanis N, Graham RR, Ioannidis JP, Daly MJ, Seddon JM. Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. Ophthalmology. 2012 Sep; 119(9):1874-85. PMID: 22705344.
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    47. Lim LS, Mitchell P, Seddon JM, Holz FG, Wong TY. Age-related macular degeneration. Lancet. 2012 May 05; 379(9827):1728-38. PMID: 22559899.
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    48. Yu Y, Reynolds R, Rosner B, Daly MJ, Seddon JM. Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models. Invest Ophthalmol Vis Sci. 2012 Mar; 53(3):1548-56. PMID: 22247473; PMCID: PMC3339916.
    49. Kleinerman RA, Yu CL, Little MP, Li Y, Abramson D, Seddon J, Tucker MA. Variation of second cancer risk by family history of retinoblastoma among long-term survivors. J Clin Oncol. 2012 Mar 20; 30(9):950-7. PMID: 22355046; PMCID: PMC3341108.
    50. Quellec G, Russell SR, Seddon JM, Reynolds R, Scheetz T, Mahajan VB, Stone EM, Abràmoff MD. Automated discovery and quantification of image-based complex phenotypes: a twin study of drusen phenotypes in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2011 Nov 25; 52(12):9195-206. PMID: 22039249; PMCID: PMC3302481.
    51. Stanton CM, Yates JR, den Hollander AI, Seddon JM, Swaroop A, Stambolian D, Fauser S, Hoyng C, Yu Y, Atsuhiro K, Branham K, Othman M, Chen W, Kortvely E, Chalmers K, Hayward C, Moore AT, Dhillon B, Ueffing M, Wright AF. Complement factor D in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2011 Nov 11; 52(12):8828-34. PMID: 22003108; PMCID: PMC3230905.
    52. Raychaudhuri S, Iartchouk O, Chin K, Tan PL, Tai AK, Ripke S, Gowrisankar S, Vemuri S, Montgomery K, Yu Y, Reynolds R, Zack DJ, Campochiaro B, Campochiaro P, Katsanis N, Daly MJ, Seddon JM. A rare penetrant mutation in CFH confers high risk of age-related macular degeneration. Nat Genet. 2011 Oct 23; 43(12):1232-6. PMID: 22019782; PMCID: PMC3225644.
    53. Francis JH, Kleinerman RA, Seddon JM, Abramson DH. Increased risk of secondary uterine leiomyosarcoma in hereditary retinoblastoma. Gynecol Oncol. 2012 Feb; 124(2):254-9. PMID: 22027510; PMCID: PMC3264733.
    54. Seddon JM, Reynolds R, Yu Y, Daly MJ, Rosner B. Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors. Ophthalmology. 2011 Nov; 118(11):2203-11. PMID: 21959373; PMCID: PMC4097877.
    55. McKay GJ, Patterson CC, Chakravarthy U, Dasari S, Klaver CC, Vingerling JR, Ho L, de Jong PT, Fletcher AE, Young IS, Seland JH, Rahu M, Soubrane G, Tomazzoli L, Topouzis F, Vioque J, Hingorani AD, Sofat R, Dean M, Sawitzke J, Seddon JM, Peter I, Webster AR, Moore AT, Yates JR, Cipriani V, Fritsche LG, Weber BH, Keilhauer CN, Lotery AJ, Ennis S, Klein ML, Francis PJ, Stambolian D, Orlin A, Gorin MB, Weeks DE, Kuo CL, Swaroop A, Othman M, Kanda A, Chen W, Abecasis GR, Wright AF, Hayward C, Baird PN, Guymer RH, Attia J, Thakkinstian A, Silvestri G. Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies. Hum Mutat. 2011 Dec; 32(12):1407-16. PMID: 21882290.
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    56. Peter I, Huggins GS, Ordovas JM, Haan M, Seddon JM. Evaluation of new and established age-related macular degeneration susceptibility genes in the Women's Health Initiative Sight Exam (WHI-SE) Study. Am J Ophthalmol. 2011 Dec; 152(6):1005-1013.e1. PMID: 21906714; PMCID: PMC4446967.
    57. Yu Y, Reynolds R, Fagerness J, Rosner B, Daly MJ, Seddon JM. Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration. Invest Ophthalmol Vis Sci. 2011 Jun 28; 52(7):4663-70. PMID: 21447678; PMCID: PMC3175969.
    58. Yu Y, Bhangale TR, Fagerness J, Ripke S, Thorleifsson G, Tan PL, Souied EH, Richardson AJ, Merriam JE, Buitendijk GH, Reynolds R, Raychaudhuri S, Chin KA, Sobrin L, Evangelou E, Lee PH, Lee AY, Leveziel N, Zack DJ, Campochiaro B, Campochiaro P, Smith RT, Barile GR, Guymer RH, Hogg R, Chakravarthy U, Robman LD, Gustafsson O, Sigurdsson H, Ortmann W, Behrens TW, Stefansson K, Uitterlinden AG, van Duijn CM, Vingerling JR, Klaver CC, Allikmets R, Brantley MA, Baird PN, Katsanis N, Thorsteinsdottir U, Ioannidis JP, Daly MJ, Graham RR, Seddon JM. Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Hum Mol Genet. 2011 Sep 15; 20(18):3699-709. PMID: 21665990; PMCID: PMC3159552.
    59. Wise LA, Rosenberg L, Radin RG, Mattox C, Yang EB, Palmer JR, Seddon JM. A prospective study of diabetes, lifestyle factors, and glaucoma among African-American women. Ann Epidemiol. 2011 Jun; 21(6):430-9. PMID: 21549278; PMCID: PMC3091261.
    60. Seddon JM, Reynolds R, Shah HR, Rosner B. Smoking, dietary betaine, methionine, and vitamin D in monozygotic twins with discordant macular degeneration: epigenetic implications. Ophthalmology. 2011 Jul; 118(7):1386-94. PMID: 21620475; PMCID: PMC3711586.
    61. McKay GJ, Silvestri G, Chakravarthy U, Dasari S, Fritsche LG, Weber BH, Keilhauer CN, Klein ML, Francis PJ, Klaver CC, Vingerling JR, Ho L, De Jong PT, Dean M, Sawitzke J, Baird PN, Guymer RH, Stambolian D, Orlin A, Seddon JM, Peter I, Wright AF, Hayward C, Lotery AJ, Ennis S, Gorin MB, Weeks DE, Kuo CL, Hingorani AD, Sofat R, Cipriani V, Swaroop A, Othman M, Kanda A, Chen W, Abecasis GR, Yates JR, Webster AR, Moore AT, Seland JH, Rahu M, Soubrane G, Tomazzoli L, Topouzis F, Vioque J, Young IS, Fletcher AE, Patterson CC. Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people. Am J Epidemiol. 2011 Jun 15; 173(12):1357-64. PMID: 21498624; PMCID: PMC3145394.
    62. Weiner DE, Tighiouart H, Reynolds R, Seddon JM. Kidney function, albuminuria and age-related macular degeneration in NHANES III. Nephrol Dial Transplant. 2011 Oct; 26(10):3159-65. PMID: 21339308; PMCID: PMC3247860.
    63. Sobrin L, Reynolds R, Yu Y, Fagerness J, Leveziel N, Bernstein PS, Souied EH, Daly MJ, Seddon JM. ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration. Am J Ophthalmol. 2011 Feb; 151(2):345-52.e3. PMID: 21122828; PMCID: PMC3763907.
    64. Seddon JM, Reynolds R, Rosner B. Associations of smoking, body mass index, dietary lutein, and the LIPC gene variant rs10468017 with advanced age-related macular degeneration. Mol Vis. 2010 Nov 17; 16:2412-24. PMID: 21139980; PMCID: PMC2994762.
    65. Reynolds R, Rosner B, Seddon JM. Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration. Ophthalmology. 2010 Oct; 117(10):1989-95. PMID: 20888482; PMCID: PMC3081670.
    66. Peter I, Seddon JM. Genetic epidemiology: successes and challenges of genome-wide association studies using the example of age-related macular degeneration. Am J Ophthalmol. 2010 Oct; 150(4):450-452.e2. PMID: 20863920; PMCID: PMC3711490.
    67. Raychaudhuri S, Ripke S, Li M, Neale BM, Fagerness J, Reynolds R, Sobrin L, Swaroop A, Abecasis G, Seddon JM, Daly MJ. Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent. Nat Genet. 2010 Jul; 42(7):553-5; author reply 555-6. PMID: 20581873; PMCID: PMC3138072.
    68. Jun JJ, Duker JS, Baumal CR, McCabe F, Reichel E, Rogers AH, Seddon JM, Tolentino FI. Cystoid macular edema without macular thickening: a retrospective optical coherence tomographic study. Retina. 2010 Jun; 30(6):917-23. PMID: 20168270.
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    69. Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL. Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7401-6. PMID: 20385819.
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    70. Neale BM, Fagerness J, Reynolds R, Sobrin L, Parker M, Raychaudhuri S, Tan PL, Oh EC, Merriam JE, Souied E, Bernstein PS, Li B, Frederick JM, Zhang K, Brantley MA, Lee AY, Zack DJ, Campochiaro B, Campochiaro P, Ripke S, Smith RT, Barile GR, Katsanis N, Allikmets R, Daly MJ, Seddon JM. Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7395-400. PMID: 20385826; PMCID: PMC2867697.
    71. Seddon JM, Gensler G, Rosner B. C-reactive protein and CFH, ARMS2/HTRA1 gene variants are independently associated with risk of macular degeneration. Ophthalmology. 2010 Aug; 117(8):1560-6. PMID: 20346514; PMCID: PMC3711558.
    72. Seddon JM, Berggren KT, Fleeman LM. Evolutionary history of DLA class II haplotypes in canine diabetes mellitus through single nucleotide polymorphism genotyping. Tissue Antigens. 2010 Mar; 75(3):218-26. PMID: 20047645.
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    73. Chodick G, Kleinerman RA, Stovall M, Abramson DH, Seddon JM, Smith SA, Tucker MA. Risk of cataract extraction among adult retinoblastoma survivors. Arch Ophthalmol. 2009 Nov; 127(11):1500-4. PMID: 19901216.
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    74. Sobrin L, Maller JB, Neale BM, Reynolds RC, Fagerness JA, Daly MJ, Seddon JM. Genetic profile for five common variants associated with age-related macular degeneration in densely affected families: a novel analytic approach. Eur J Hum Genet. 2010 Apr; 18(4):496-501. PMID: 19844262; PMCID: PMC2911949.
    75. Zerbib J, Seddon JM, Richard F, Reynolds R, Leveziel N, Benlian P, Borel P, Feingold J, Munnich A, Soubrane G, Kaplan J, Rozet JM, Souied EH. rs5888 variant of SCARB1 gene is a possible susceptibility factor for age-related macular degeneration. PLoS One. 2009 Oct 05; 4(10):e7341. PMID: 19806217; PMCID: PMC2752725.
    76. Reynolds R, Hartnett ME, Atkinson JP, Giclas PC, Rosner B, Seddon JM. Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes. Invest Ophthalmol Vis Sci. 2009 Dec; 50(12):5818-27. PMID: 19661236; PMCID: PMC2826794.
    77. Edwards AO, Swaroop A, Seddon JM. Geographic atrophy in age-related macular degeneration and TLR3. N Engl J Med. 2009 May 21; 360(21):2254-5; author reply 2255-6. PMID: 19469037.
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    78. Yu CL, Tucker MA, Abramson DH, Furukawa K, Seddon JM, Stovall M, Fraumeni JF, Kleinerman RA. Cause-specific mortality in long-term survivors of retinoblastoma. J Natl Cancer Inst. 2009 Apr 15; 101(8):581-91. PMID: 19351917; PMCID: PMC2669101.
    79. Seddon JM, Reynolds R, Maller J, Fagerness JA, Daly MJ, Rosner B. Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables. Invest Ophthalmol Vis Sci. 2009 May; 50(5):2044-53. PMID: 19117936; PMCID: PMC3772781.
    80. Seddon JM, Reynolds R, Rosner B. Peripheral retinal drusen and reticular pigment: association with CFHY402H and CFHrs1410996 genotypes in family and twin studies. Invest Ophthalmol Vis Sci. 2009 Feb; 50(2):586-91. PMID: 18936151.
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    81. SanGiovanni JP, Chew EY, Agrón E, Clemons TE, Ferris FL, Gensler G, Lindblad AS, Milton RC, Seddon JM, Klein R, Sperduto RD. The relationship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23. Arch Ophthalmol. 2008 Sep; 126(9):1274-9. PMID: 18779490.
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    82. Yi K, Mujat M, Park BH, Sun W, Miller JW, Seddon JM, Young LH, de Boer JF, Chen TC. Spectral domain optical coherence tomography for quantitative evaluation of drusen and associated structural changes in non-neovascular age-related macular degeneration. Br J Ophthalmol. 2009 Feb; 93(2):176-81. PMID: 18697811; PMCID: PMC2628537.
    83. Fagerness JA, Maller JB, Neale BM, Reynolds RC, Daly MJ, Seddon JM. Variation near complement factor I is associated with risk of advanced AMD. Eur J Hum Genet. 2009 Jan; 17(1):100-4. PMID: 18685559; PMCID: PMC2985963.
    84. Sheen V, Tucker MA, Abramson DH, Seddon JM, Kleinerman RA. Cancer screening practices of adult survivors of retinoblastoma at risk of second cancers. Cancer. 2008 Jul 15; 113(2):434-41. PMID: 18473349.
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    85. Maki J, Kusakul S, Morley K, Sanguansak T, Seddon J, Hartung L, Morley M. The effect of glasses on visual function following cataract surgery in a cataract camp. Br J Ophthalmol. 2008 Jul; 92(7):883-7. PMID: 18577636.
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    86. Klein ML, Francis PJ, Rosner B, Reynolds R, Hamon SC, Schultz DW, Ott J, Seddon JM. CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration. Ophthalmology. 2008 Jun; 115(6):1019-25. PMID: 18423869.
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    87. Montezuma SR, Sobrin L, Seddon JM. Review of genetics in age related macular degeneration. Semin Ophthalmol. 2007 Oct-Dec; 22(4):229-40. PMID: 18097986.
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    88. Maller JB, Fagerness JA, Reynolds RC, Neale BM, Daly MJ, Seddon JM. Variation in complement factor 3 is associated with risk of age-related macular degeneration. Nat Genet. 2007 Oct; 39(10):1200-1. PMID: 17767156.
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    89. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol. 2007 Sep; 125(9):1225-32. PMID: 17846363.
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    90. SanGiovanni JP, Chew EY, Clemons TE, Davis MD, Ferris FL, Gensler GR, Kurinij N, Lindblad AS, Milton RC, Seddon JM, Sperduto RD. The relationship of dietary lipid intake and age-related macular degeneration in a case-control study: AREDS Report No. 20. Arch Ophthalmol. 2007 May; 125(5):671-9. PMID: 17502507.
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    91. Seddon JM, Francis PJ, George S, Schultz DW, Rosner B, Klein ML. Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration. JAMA. 2007 Apr 25; 297(16):1793-800. PMID: 17456821.
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    92. Kennedy LJ, Barnes A, Short A, Brown JJ, Lester S, Seddon J, Happ GM, Ollier WE. Canine DLA diversity: 2. Family studies. Tissue Antigens. 2007 Apr; 69 Suppl 1:289-91. PMID: 17445219.
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    93. Kennedy LJ, Barnes A, Short A, Brown JJ, Lester S, Seddon J, Fleeman L, Francino O, Brkljacic M, Knyazev S, Happ GM, Ollier WE. Canine DLA diversity: 1. New alleles and haplotypes. Tissue Antigens. 2007 Apr; 69 Suppl 1:272-88. PMID: 17445218.
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    94. Francis PJ, George S, Schultz DW, Rosner B, Hamon S, Ott J, Weleber RG, Klein ML, Seddon JM. The LOC387715 gene, smoking, body mass index, environmental associations with advanced age-related macular degeneration. Hum Hered. 2007; 63(3-4):212-8. PMID: 17347568.
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    95. Klein R, Deng Y, Klein BE, Hyman L, Seddon J, Frank RN, Wallace RB, Hendrix SL, Kuppermann BD, Langer RD, Kuller L, Brunner R, Johnson KC, Thomas AM, Haan M. Cardiovascular disease, its risk factors and treatment, and age-related macular degeneration: Women's Health Initiative Sight Exam ancillary study. Am J Ophthalmol. 2007 Mar; 143(3):473-83. PMID: 17317391; PMCID: PMC2812860.
    96. Kleinerman RA, Tucker MA, Abramson DH, Seddon JM, Tarone RE, Fraumeni JF. Risk of soft tissue sarcomas by individual subtype in survivors of hereditary retinoblastoma. J Natl Cancer Inst. 2007 Jan 03; 99(1):24-31. PMID: 17202110.
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    97. Seddon JM. Multivitamin-multimineral supplements and eye disease: age-related macular degeneration and cataract. Am J Clin Nutr. 2007 Jan; 85(1):304S-307S. PMID: 17209215.
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    98. O'Leary CA, Duffy D, Biros I, Corley S, Seddon JM. Linkage analysis excludes the involvement of the canine PKD2 homologue in bull terrier polycystic kidney disease. Anim Genet. 2006 Oct; 37(5):527-8. PMID: 16978192.
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    99. Maller J, George S, Purcell S, Fagerness J, Altshuler D, Daly MJ, Seddon JM. Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet. 2006 Sep; 38(9):1055-9. PMID: 16936732.
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    100. Foster MC, Kleinerman RA, Abramson DH, Seddon JM, Tarone RE, Tucker MA. Tobacco use in adult long-term survivors of retinoblastoma. Cancer Epidemiol Biomarkers Prev. 2006 Aug; 15(8):1464-8. PMID: 16896033.
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    101. Haan MN, Klein R, Klein BE, Deng Y, Blythe LK, Seddon JM, Musch DC, Kuller LH, Hyman LG, Wallace RB. Hormone therapy and age-related macular degeneration: the Women's Health Initiative Sight Exam Study. Arch Ophthalmol. 2006 Jul; 124(7):988-92. PMID: 16832022.
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    102. Haddad S, Chen CA, Santangelo SL, Seddon JM. The genetics of age-related macular degeneration: a review of progress to date. Surv Ophthalmol. 2006 Jul-Aug; 51(4):316-63. PMID: 16818082.
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    103. Seddon JM, George S, Rosner B. Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US Twin Study of Age-Related Macular Degeneration. Arch Ophthalmol. 2006 Jul; 124(7):995-1001. PMID: 16832023.
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    105. Seddon JM, Gensler G, Klein ML, Milton RC. C-reactive protein and homocysteine are associated with dietary and behavioral risk factors for age-related macular degeneration. Nutrition. 2006 Apr; 22(4):441-3. PMID: 16530626.
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    106. Seddon JM, Sharma S, Adelman RA. Evaluation of the clinical age-related maculopathy staging system. Ophthalmology. 2006 Feb; 113(2):260-6. PMID: 16458093.
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    108. Young TA, Seddon JM. Choroidal and cutaneous melanoma: distinctly different cousins. Ophthalmic Epidemiol. 2005 Aug; 12(4):221-2. PMID: 16033742.
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    109. Fisher SA, Abecasis GR, Yashar BM, Zareparsi S, Swaroop A, Iyengar SK, Klein BE, Klein R, Lee KE, Majewski J, Schultz DW, Klein ML, Seddon JM, Santangelo SL, Weeks DE, Conley YP, Mah TS, Schmidt S, Haines JL, Pericak-Vance MA, Gorin MB, Schulz HL, Pardi F, Lewis CM, Weber BH. Meta-analysis of genome scans of age-related macular degeneration. Hum Mol Genet. 2005 Aug 01; 14(15):2257-64. PMID: 15987700.
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    110. Seddon JM, George S, Rosner B, Rifai N. Progression of age-related macular degeneration: prospective assessment of C-reactive protein, interleukin 6, and other cardiovascular biomarkers. Arch Ophthalmol. 2005 Jun; 123(6):774-82. PMID: 15955978.
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    111. Santangelo SL, Yen CH, Haddad S, Fagerness J, Huang C, Seddon JM. A discordant sib-pair linkage analysis of age-related macular degeneration. Ophthalmic Genet. 2005 Jun; 26(2):61-7. PMID: 16020308.
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    112. Kleinerman RA, Tucker MA, Tarone RE, Abramson DH, Seddon JM, Stovall M, Li FP, Fraumeni JF. Risk of new cancers after radiotherapy in long-term survivors of retinoblastoma: an extended follow-up. J Clin Oncol. 2005 Apr 01; 23(10):2272-9. PMID: 15800318.
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    113. Clemons TE, Milton RC, Klein R, Seddon JM, Ferris FL. Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19. Ophthalmology. 2005 Apr; 112(4):533-9. PMID: 15808240; PMCID: PMC1513667.
    114. Seddon JM, Cote J, Page WF, Aggen SH, Neale MC. The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences. Arch Ophthalmol. 2005 Mar; 123(3):321-7. PMID: 15767473.
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    115. Seddon JM, Ellegren H. A temporal analysis shows major histocompatibility complex loci in the Scandinavian wolf population are consistent with neutral evolution. Proc Biol Sci. 2004 Nov 07; 271(1554):2283-91. PMID: 15539354; PMCID: PMC1691861.
    116. Schaumberg DA, Liu S, Seddon JM, Willett WC, Hankinson SE. Dietary glycemic load and risk of age-related cataract. Am J Clin Nutr. 2004 Aug; 80(2):489-95. PMID: 15277175.
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    117. Cho E, Seddon JM, Rosner B, Willett WC, Hankinson SE. Prospective study of intake of fruits, vegetables, vitamins, and carotenoids and risk of age-related maculopathy. Arch Ophthalmol. 2004 Jun; 122(6):883-92. PMID: 15197064.
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    118. Seddon JM, Gensler G, Milton RC, Klein ML, Rifai N. Association between C-reactive protein and age-related macular degeneration. JAMA. 2004 Feb 11; 291(6):704-10. PMID: 14871913.
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    119. Seddon JM, Chen CA. The epidemiology of age-related macular degeneration. Int Ophthalmol Clin. 2004; 44(4):17-39. PMID: 15577562.
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    120. Seddon JM, Cote J, Rosner B. Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake. Arch Ophthalmol. 2003 Dec; 121(12):1728-37. PMID: 14662593.
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    121. Bressler NM, Bressler SB, Congdon NG, Ferris FL, Friedman DS, Klein R, Lindblad AS, Milton RC, Seddon JM. Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11. Arch Ophthalmol. 2003 Nov; 121(11):1621-4. PMID: 14609922; PMCID: PMC1473209.
    122. Seddon JM, Sharma S, Chong S, Hutchinson A, Allikmets R, Adelman RA. Phenotype and genotype correlations in two best families. Ophthalmology. 2003 Sep; 110(9):1724-31. PMID: 13129869.
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    123. Seddon JM, Santangelo SL, Book K, Chong S, Cote J. A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions. Am J Hum Genet. 2003 Oct; 73(4):780-90. PMID: 12945014; PMCID: PMC1180601.
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    125. Snow KK, Cote J, Yang W, Davis NJ, Seddon JM. Association between reproductive and hormonal factors and age-related maculopathy in postmenopausal women. Am J Ophthalmol. 2002 Dec; 134(6):842-8. PMID: 12470752.
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    126. Weintraub JM, Willett WC, Rosner B, Colditz GA, Seddon JM, Hankinson SE. A prospective study of the relationship between body mass index and cataract extraction among US women and men. Int J Obes Relat Metab Disord. 2002 Dec; 26(12):1588-95. PMID: 12461675.
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    127. Bernstein PS, Leppert M, Singh N, Dean M, Lewis RA, Lupski JR, Allikmets R, Seddon JM. Genotype-phenotype analysis of ABCR variants in macular degeneration probands and siblings. Invest Ophthalmol Vis Sci. 2002 Feb; 43(2):466-73. PMID: 11818392.
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    128. Weintraub JM, Willett WC, Rosner B, Colditz GA, Seddon JM, Hankinson SE. Smoking cessation and risk of cataract extraction among US women and men. Am J Epidemiol. 2002 Jan 01; 155(1):72-9. PMID: 11772787.
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    129. Ayyagari R, Zhang K, Hutchinson A, Yu Z, Swaroop A, Kakuk LE, Seddon JM, Bernstein PS, Lewis RA, Tammur J, Yang Z, Li Y, Zhang H, Yashar BM, Liu J, Petrukhin K, Sieving PA, Allikmets R. Evaluation of the ELOVL4 gene in patients with age-related macular degeneration. Ophthalmic Genet. 2001 Dec; 22(4):233-9. PMID: 11803489.
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    130. Seddon JM, Afshari MA, Sharma S, Bernstein PS, Chong S, Hutchinson A, Petrukhin K, Allikmets R. Assessment of mutations in the Best macular dystrophy (VMD2) gene in patients with adult-onset foveomacular vitelliform dystrophy, age-related maculopathy, and bull's-eye maculopathy. Ophthalmology. 2001 Nov; 108(11):2060-7. PMID: 11713080.
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    131. Seddon JM, Rosner B, Sperduto RD, Yannuzzi L, Haller JA, Blair NP, Willett W. Dietary fat and risk for advanced age-related macular degeneration. Arch Ophthalmol. 2001 Aug; 119(8):1191-9. PMID: 11483088.
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    132. Cho E, Stampfer MJ, Seddon JM, Hung S, Spiegelman D, Rimm EB, Willett WC, Hankinson SE. Prospective study of zinc intake and the risk of age-related macular degeneration. Ann Epidemiol. 2001 Jul; 11(5):328-36. PMID: 11399447.
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    134. Kleinerman RA, Tarone RE, Abramson DH, Seddon JM, Li FP, Tucker MA. Hereditary retinoblastoma and risk of lung cancer. J Natl Cancer Inst. 2000 Dec 20; 92(24):2037-9. PMID: 11121467.
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    135. McCabe P, Nason F, Demers Turco P, Friedman D, Seddon JM. Evaluating the effectiveness of a vision rehabilitation intervention using an objective and subjective measure of functional performance. Ophthalmic Epidemiol. 2000 Dec; 7(4):259-70. PMID: 11262673.
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    136. Snow KK, Seddon JM. Age-related eye diseases: impact of hormone replacement therapy, and reproductive and other risk factors. Int J Fertil Womens Med. 2000 Sep-Oct; 45(5):301-13. PMID: 11092701.
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    137. Chasan-Taber L, Willett WC, Seddon JM, Stampfer MJ, Rosner B, Colditz GA, Speizer FE, Hankinson SE. A prospective study of alcohol consumption and cataract extraction among U.S. women. Ann Epidemiol. 2000 Aug; 10(6):347-53. PMID: 10964000.
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    138. Li W, Judge H, Gragoudas ES, Seddon JM, Egan KM. Patterns of tumor initiation in choroidal melanoma. Cancer Res. 2000 Jul 15; 60(14):3757-60. PMID: 10919647.
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    139. Ghosh P, Hale EA, Mayur K, Seddon J, Lakshman MR. Effects of chronic alcohol treatment on the synthesis, sialylation, and disposition of nascent apolipoprotein E by peritoneal macrophages of rats. Am J Clin Nutr. 2000 Jul; 72(1):190-8. PMID: 10871579.
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    140. Gragoudas ES, Lane AM, Regan S, Li W, Judge HE, Munzenrider JE, Seddon JM, Egan KM. A randomized controlled trial of varying radiation doses in the treatment of choroidal melanoma. Arch Ophthalmol. 2000 Jun; 118(6):773-8. PMID: 10865313.
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    141. Seddon JM, Baverstock PR. Evolutionary lineages of RT1.Ba in the Australian Rattus. Mol Biol Evol. 2000 May; 17(5):768-72. PMID: 10779537.
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    143. Gorin MB, Breitner JC, De Jong PT, Hageman GS, Klaver CC, Kuehn MH, Seddon JM. The genetics of age-related macular degeneration. Mol Vis. 1999 Nov 03; 5:29. PMID: 10562653.
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    146. Brown L, Rimm EB, Seddon JM, Giovannucci EL, Chasan-Taber L, Spiegelman D, Willett WC, Hankinson SE. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr. 1999 Oct; 70(4):517-24. PMID: 10500021.
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    147. Mangione CM, Gutierrez PR, Lowe G, Orav EJ, Seddon JM. Influence of age-related maculopathy on visual functioning and health-related quality of life. Am J Ophthalmol. 1999 Jul; 128(1):45-53. PMID: 10482093.
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    148. Allikmets R, Seddon JM, Bernstein PS, Hutchinson A, Atkinson A, Sharma S, Gerrard B, Li W, Metzker ML, Wadelius C, Caskey CT, Dean M, Petrukhin K. Evaluation of the Best disease gene in patients with age-related macular degeneration and other maculopathies. Hum Genet. 1999 Jun; 104(6):449-53. PMID: 10453731.
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    149. Snow KK, Seddon JM. Do age-related macular degeneration and cardiovascular disease share common antecedents? Ophthalmic Epidemiol. 1999 Jun; 6(2):125-43. PMID: 10420212.
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    151. Sperduto RD, Hiller R, Chew E, Seigel D, Blair N, Burton TC, Farber MD, Gragoudas ES, Haller J, Seddon JM, Yannuzzi LA. Risk factors for hemiretinal vein occlusion: comparison with risk factors for central and branch retinal vein occlusion: the eye disease case-control study. Ophthalmology. 1998 May; 105(5):765-71. PMID: 9593373.
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    152. Wong FL, Boice JD, Abramson DH, Tarone RE, Kleinerman RA, Stovall M, Goldman MB, Seddon JM, Tarbell N, Fraumeni JF, Li FP. Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk. JAMA. 1997 Oct 15; 278(15):1262-7. PMID: 9333268.
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    153. Allikmets R, Shroyer NF, Singh N, Seddon JM, Lewis RA, Bernstein PS, Peiffer A, Zabriskie NA, Li Y, Hutchinson A, Dean M, Lupski JR, Leppert M. Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science. 1997 Sep 19; 277(5333):1805-7. PMID: 9295268.
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    155. De La Paz MA, Pericak-Vance MA, Lennon F, Haines JL, Seddon JM. Exclusion of TIMP3 as a candidate locus in age-related macular degeneration. Invest Ophthalmol Vis Sci. 1997 May; 38(6):1060-5. PMID: 9152225.
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    156. Seddon JM, Ajani UA, Mitchell BD. Familial aggregation of age-related maculopathy. Am J Ophthalmol. 1997 Feb; 123(2):199-206. PMID: 9186125.
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    158. Bernstein PS, Seddon JM. Decision-making in the treatment of subfoveal neovascularization in age-related macular degeneration. An analysis from the patient's perspective. Retina. 1996; 16(2):112-6. PMID: 8724953.
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    160. Mangione CM, Orav EJ, Lawrence MG, Phillips RS, Seddon JM, Goldman L. Prediction of visual function after cataract surgery. A prospectively validated model. Arch Ophthalmol. 1995 Oct; 113(10):1305-11. PMID: 7575265.
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    162. Mangione CM, Phillips RS, Lawrence MG, Seddon JM, Orav EJ, Goldman L. Improved visual function and attenuation of declines in health-related quality of life after cataract extraction. Arch Ophthalmol. 1994 Nov; 112(11):1419-25. PMID: 7980131.
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    163. Christen WG, Glynn RJ, Seddon JM, Manson JE, Buring JE, Hennekens CH. Confirmation of self-reported cataract in the Physicians' Health Study. Ophthalmic Epidemiol. 1994 Jun; 1(2):85-91. PMID: 8790615.
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    164. Manson JE, Christen WG, Seddon JM, Glynn RJ, Hennekens CH. A prospective study of alcohol consumption and risk of cataract. Am J Prev Med. 1994 May-Jun; 10(3):156-61. PMID: 7917442.
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    165. Ajani UA, Willett WC, Seddon JM. Reproducibility of a food frequency questionnaire for use in ocular research. Eye Disease Case-Control Study Group. Invest Ophthalmol Vis Sci. 1994 May; 35(6):2725-33. PMID: 8188466.
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    166. Seddon JM, Christen WG, Manson JE, LaMotte FS, Glynn RJ, Buring JE, Hennekens CH. The use of vitamin supplements and the risk of cataract among US male physicians. Am J Public Health. 1994 May; 84(5):788-92. PMID: 8179050; PMCID: PMC1615060.
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    168. Seddon J, Fong D. Introducing "public health and the eye". Surv Ophthalmol. 1994 Jan-Feb; 38(4):325. PMID: 8160106.
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    169. Fong DS, Seddon JM. Diagnostic tests: an overview. Int Ophthalmol Clin. 1994; 34(3):187-95. PMID: 7960513.
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    170. Gragoudas ES, Egan KM, Saornil MA, Walsh SM, Albert DM, Seddon JM. The time course of irradiation changes in proton beam-treated uveal melanomas. Ophthalmology. 1993 Oct; 100(10):1555-9; discussion 1560. PMID: 8414415.
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    171. Egan KM, Walsh SM, Seddon JM, Gragoudas ES. An evaluation of the influence of reproductive factors on the risk of metastases from uveal melanoma. Ophthalmology. 1993 Aug; 100(8):1160-5; discussion 1166. PMID: 8341495.
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    172. Eng C, Li FP, Abramson DH, Ellsworth RM, Wong FL, Goldman MB, Seddon J, Tarbell N, Boice JD. Mortality from second tumors among long-term survivors of retinoblastoma. J Natl Cancer Inst. 1993 Jul 21; 85(14):1121-8. PMID: 8320741.
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    173. Mangione CM, Seddon JM, Cook EF, Krug JH, Sahagian CR, Campion EW, Glynn RJ. Correlates of cognitive function scores in elderly outpatients. J Am Geriatr Soc. 1993 May; 41(5):491-7. PMID: 8486880.
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    174. Hankinson SE, Seddon JM, Colditz GA, Stampfer MJ, Rosner B, Speizer FE, Willett WC. A prospective study of aspirin use and cataract extraction in women. Arch Ophthalmol. 1993 Apr; 111(4):503-8. PMID: 8470984.
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    175. Weinberg DV, Egan KM, Seddon JM. Asymmetric distribution of arteriovenous crossings in the normal retina. Ophthalmology. 1993 Jan; 100(1):31-6. PMID: 8433824.
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    176. Christen WG, Seddon JM. Cigarette smoking and cataract. Am J Prev Med. 1993 Jan-Feb; 9(1):65-6. PMID: 8439443.
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    177. Ajani UA, Seddon JM, Hsieh CC, Egan KM, Albert DM, Gragoudas ES. Occupation and risk of uveal melanoma. An exploratory study. Cancer. 1992 Dec 15; 70(12):2891-900. PMID: 1451071.
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    178. Mangione CM, Phillips RS, Seddon JM, Lawrence MG, Cook EF, Dailey R, Goldman L. Development of the 'Activities of Daily Vision Scale'. A measure of visual functional status. Med Care. 1992 Dec; 30(12):1111-26. PMID: 1453816.
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    179. Hankinson SE, Willett WC, Colditz GA, Seddon JM, Rosner B, Speizer FE, Stampfer MJ. A prospective study of cigarette smoking and risk of cataract surgery in women. JAMA. 1992 Aug 26; 268(8):994-8. PMID: 1501325.
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    180. Christen WG, Manson JE, Seddon JM, Glynn RJ, Buring JE, Rosner B, Hennekens CH. A prospective study of cigarette smoking and risk of cataract in men. JAMA. 1992 Aug 26; 268(8):989-93. PMID: 1501324.
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    181. Hankinson SE, Stampfer MJ, Seddon JM, Colditz GA, Rosner B, Speizer FE, Willett WC. Nutrient intake and cataract extraction in women: a prospective study. BMJ. 1992 Aug 08; 305(6849):335-9. PMID: 1392884; PMCID: PMC1882980.
    182. Saornil MA, Egan KM, Gragoudas ES, Seddon JM, Walsh SM, Albert DM. Histopathology of proton beam-irradiated vs enucleated uveal melanomas. Arch Ophthalmol. 1992 Aug; 110(8):1112-8. PMID: 1323252.
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    183. Guyer DR, Mukai S, Egan KM, Seddon JM, Walsh SM, Gragoudas ES. Radiation maculopathy after proton beam irradiation for choroidal melanoma. Ophthalmology. 1992 Aug; 99(8):1278-85. PMID: 1325044.
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    184. Seddon JM, Egan KM, Zhang Y, Gelles EJ, Glynn RJ, Tucker CA, Gragoudas ES. Evaluation of skin microtopography as a measure of ultraviolet exposure. Invest Ophthalmol Vis Sci. 1992 May; 33(6):1903-8. PMID: 1582796.
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    185. Gragoudas ES, Egan KM, Seddon JM, Walsh SM, Munzenrider JE. Intraocular recurrence of uveal melanoma after proton beam irradiation. Ophthalmology. 1992 May; 99(5):760-6. PMID: 1594223.
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    186. Gragoudas ES, Egan KM, Arrigg PG, Seddon JM, Glynn RJ, Munzenrider JE. Cataract extraction after proton beam irradiation for malignant melanoma of the eye. Arch Ophthalmol. 1992 Apr; 110(4):475-9. PMID: 1562251.
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    187. Egan KM, Gragoudas ES, Seddon JM, Walsh SM. Smoking and the risk of early metastases from uveal melanoma. Ophthalmology. 1992 Apr; 99(4):537-41. PMID: 1584571.
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    188. Seddon JM. The differential burden of blindness in the United States. N Engl J Med. 1991 Nov 14; 325(20):1440-2. PMID: 1922257.
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    189. Levin LA, Seddon JM, Topping T. Retinal pigment epithelial tears associated with trauma. Am J Ophthalmol. 1991 Oct 15; 112(4):396-400. PMID: 1928241.
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    190. Seddon J, Gragoudas E, Egan K, Polivogianis L, Finn S, Albert D. Standardized data collection and coding in eye disease epidemiology: the Uveal Melanoma Data System. Ophthalmic Surg. 1991 Mar; 22(3):127-36. PMID: 2030892.
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    191. Gragoudas ES, Egan KM, Seddon JM, Glynn RJ, Walsh SM, Finn SM, Munzenrider JE, Spar MD. Survival of patients with metastases from uveal melanoma. Ophthalmology. 1991 Mar; 98(3):383-9; discussion 390. PMID: 2023760.
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    192. Glynn RJ, Seddon JM, Krug JH, Sahagian CR, Chiavelli ME, Campion EW. Falls in elderly patients with glaucoma. Arch Ophthalmol. 1991 Feb; 109(2):205-10. PMID: 1993029.
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    193. Seddon JM, Christen WG, Manson JE, Buring JE, Sperduto RD, Hennekens CH. Low-dose aspirin and risks of cataract in a randomized trial of US physicians. Arch Ophthalmol. 1991 Feb; 109(2):252-5. PMID: 1993037.
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    194. Glynn RJ, Schein OD, Seddon JM, Poggio EC, Goodfellow JR, Scardino VA, Shannon MJ, Kenyon KR. The incidence of ulcerative keratitis among aphakic contact lens wearers in New England. Arch Ophthalmol. 1991 Jan; 109(1):104-7. PMID: 1987926.
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    195. Austin KL, Palmer JR, Seddon JM, Glynn RJ, Rosenberg L, Gragoudas ES, Kaufman DW, Shapiro S. Case-control study of idiopathic retinal detachment. Int J Epidemiol. 1990 Dec; 19(4):1045-50. PMID: 2083988.
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    196. Seddon JM, Gragoudas ES, Glynn RJ, Egan KM, Albert DM, Blitzer PH. Host factors, UV radiation, and risk of uveal melanoma. A case-control study. Arch Ophthalmol. 1990 Sep; 108(9):1274-80. PMID: 2400347.
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    197. Seddon JM, Sahagian CR, Glynn RJ, Sperduto RD, Gragoudas ES. Evaluation of an iris color classification system. The Eye Disorders Case-Control Study Group. Invest Ophthalmol Vis Sci. 1990 Aug; 31(8):1592-8. PMID: 2201662.
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    198. Seddon JM, Gragoudas ES, Egan KM, Glynn RJ, Howard S, Fante RG, Albert DM. Relative survival rates after alternative therapies for uveal melanoma. Ophthalmology. 1990 Jun; 97(6):769-77. PMID: 2374681.
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    199. Smith EV, Kolodny NH, Gragoudas ES, Egan KM, Finn S, D'Amico DJ, Seddon JM. An NMR blood test for uveal melanoma? Invest Ophthalmol Vis Sci. 1990 May; 31(5):993-7. PMID: 2335461.
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    200. Lischko AM, Seddon JM, Gragoudas ES, Egan KM, Glynn RJ. Evaluation of prior primary malignancy as a determinant of uveal melanoma. A case-control study. Ophthalmology. 1989 Dec; 96(12):1716-21. PMID: 2622616.
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    201. Glynn RJ, Seddon JM, Gragoudas ES, Egan KM, Hart LJ. Evaluation of tumor regression and other prognostic factors for early and late metastasis after proton irradiation of uveal melanoma. Ophthalmology. 1989 Oct; 96(10):1566-73. PMID: 2685710.
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    202. Poggio EC, Glynn RJ, Schein OD, Seddon JM, Shannon MJ, Scardino VA, Kenyon KR. The incidence of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses. N Engl J Med. 1989 Sep 21; 321(12):779-83. PMID: 2770809.
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    203. Schein OD, Glynn RJ, Poggio EC, Seddon JM, Kenyon KR. The relative risk of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses. A case-control study. Microbial Keratitis Study Group. N Engl J Med. 1989 Sep 21; 321(12):773-8. PMID: 2671733.
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    204. Egan KM, Gragoudas ES, Seddon JM, Glynn RJ, Munzenreider JE, Goitein M, Verhey L, Urie M, Koehler A. The risk of enucleation after proton beam irradiation of uveal melanoma. Ophthalmology. 1989 Sep; 96(9):1377-82; discussion 1382-3. PMID: 2550868.
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    205. Flotte TJ, Seddon JM, Zhang YQ, Glynn RJ, Egan KM, Gragoudas ES. A computerized image analysis method for measuring elastic tissue. J Invest Dermatol. 1989 Sep; 93(3):358-62. PMID: 2475547.
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    206. Munzenrider JE, Verhey LJ, Gragoudas ES, Seddon JM, Urie M, Gentry R, Birnbaum S, Ruotolo DM, Crowell C, McManus P, et al. Conservative treatment of uveal melanoma: local recurrence after proton beam therapy. Int J Radiat Oncol Biol Phys. 1989 Sep; 17(3):493-8. PMID: 2550395.
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    207. Friedman E, Ivry M, Ebert E, Glynn R, Gragoudas E, Seddon J. Increased scleral rigidity and age-related macular degeneration. Ophthalmology. 1989 Jan; 96(1):104-8. PMID: 2919041.
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    208. Polivogianis L, Seddon JM, Glynn RJ, Gragoudas ES, Albert DM. Comparison of transillumination and histologic slide measurements of tumor diameter in uveal melanoma. Ophthalmology. 1988 Nov; 95(11):1576-82. PMID: 3062526.
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    209. Munzenrider JE, Gragoudas ES, Seddon JM, Sisterson J, McNulty P, Birnbaum S, Johnson K, Austin-Seymour M, Slater J, Goitein MM, et al. Conservative treatment of uveal melanoma: probability of eye retention after proton treatment. Int J Radiat Oncol Biol Phys. 1988 Sep; 15(3):553-8. PMID: 2843486.
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    210. Gragoudas ES, Seddon JM, Egan KM, Glynn RJ, Goitein M, Munzenrider J, Verhey L, Urie M, Koehler A. Metastasis from uveal melanoma after proton beam irradiation. Ophthalmology. 1988 Jul; 95(7):992-9. PMID: 2845324.
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    211. Adams KS, Abramson DH, Ellsworth RM, Haik BG, Bedford M, Packer S, Seddon J, Albert D, Polivogianis L. Cobalt plaque versus enucleation for uveal melanoma: comparison of survival rates. Br J Ophthalmol. 1988 Jul; 72(7):494-7. PMID: 3415941; PMCID: PMC1041512.
    212. Glynn RJ, Seddon JM, Berlin BM. The incidence of eye injuries in New England adults. Arch Ophthalmol. 1988 Jun; 106(6):785-9. PMID: 3370007.
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    213. Cevc G, Seddon JM, Hartung R, Eggert W. Phosphatidylcholine-fatty acid membranes. I. Effects of protonation, salt concentration, temperature and chain-length on the colloidal and phase properties of mixed vesicles, bilayers and nonlamellar structures. Biochim Biophys Acta. 1988 May 24; 940(2):219-40. PMID: 2835979.
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    214. Kolodny NH, Gragoudas ES, D'Amico DJ, Seddon JM, Minichiello M, Murphy EJ, Albert DM. Preliminary results on phosphorus-31 nuclear magnetic resonance evaluation of human uveal melanoma in enucleated eyes. Ophthalmology. 1988 May; 95(5):666-73. PMID: 3174026.
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    215. Schein OD, Hibberd PL, Shingleton BJ, Kunzweiler T, Frambach DA, Seddon JM, Fontan NL, Vinger PF. The spectrum and burden of ocular injury. Ophthalmology. 1988 Mar; 95(3):300-5. PMID: 3173996.
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    216. Bressler NM, Bressler SB, Seddon JM, Gragoudas ES, Jacobson LP. Drusen characteristics in patients with exudative versus non-exudative age-related macular degeneration. Retina. 1988; 8(2):109-14. PMID: 3420311.
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    217. Egan KM, Seddon JM, Glynn RJ, Gragoudas ES, Albert DM. Epidemiologic aspects of uveal melanoma. Surv Ophthalmol. 1988 Jan-Feb; 32(4):239-51. PMID: 3279559.
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    218. Bressler SB, Bressler NM, Seddon JM, Gragoudas ES, Jacobson LP. Interobserver and intraobserver reliability in the clinical classification of drusen. Retina. 1988; 8(2):102-8. PMID: 3420310.
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    219. Kolodny NH, Gragoudas ES, D'Amico DJ, Kohler SJ, Seddon JM, Murphy EJ, Yun C, Albert DM. Proton and sodium 23 magnetic resonance imaging of human ocular tissues. A model study. Arch Ophthalmol. 1987 Nov; 105(11):1532-6. PMID: 2823760.
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    220. Seddon JM, Polivogianis L, Hsieh CC, Albert DM, Gamel JW, Gragoudas ES. Death from uveal melanoma. Number of epithelioid cells and inverse SD of nucleolar area as prognostic factors. Arch Ophthalmol. 1987 Jun; 105(6):801-6. PMID: 3579712.
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    221. Li FP, Thurber WA, Seddon J, Holmes GE. Hepatoblastoma in families with polyposis coli. JAMA. 1987 May 08; 257(18):2475-7. PMID: 3033343.
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    222. Gragoudas ES, Seddon JM, Egan K, Glynn R, Munzenrider J, Austin-Seymour M, Goitein M, Verhey L, Urie M, Koehler A. Long-term results of proton beam irradiated uveal melanomas. Ophthalmology. 1987 Apr; 94(4):349-53. PMID: 3035451.
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    223. Seddon JM, Gragoudas ES, Egan KM, Glynn RJ, Munzenrider JE, Austin-Seymour M, Goitein M, Verhey L, Urie M, Koehler A. Uveal melanomas near the optic disc or fovea. Visual results after proton beam irradiation. Ophthalmology. 1987 Apr; 94(4):354-61. PMID: 3587916.
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    224. terPenning BJ, Cheng HM, Barnett P, Seddon J, Sang D, Latina M, Aguayo J, González RG, Brady TJ. MR imaging of enucleated human eyes at 1.4 tesla. J Comput Assist Tomogr. 1986 Jul-Aug; 10(4):551-9. PMID: 3734194.
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    225. Gamel J, Seddon J, Polivogianis L, Albert D, Greenberg R. A method for assessing potential bias among cancer patients recorded as "dead of other causes." Application to cases of intraocular melanoma. Cancer. 1986 Jun 01; 57(11):2246-9. PMID: 3697925.
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    226. Seddon JM, Gragoudas ES, Polivogianis L, Hsieh CC, Egan KM, Goitein M, Verhey L, Munzenrider J, Austin-Seymour M, Urie M, et al. Visual outcome after proton beam irradiation of uveal melanoma. Ophthalmology. 1986 May; 93(5):666-74. PMID: 3014415.
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    227. Gragoudas ES, Seddon JM, Egan KM, Polivogianis L, Hsieh CC, Goitein M, Verhey L, Munzenrider J, Austin-Seymour M, Urie M, et al. Prognostic factors for metastasis following proton beam irradiation of uveal melanomas. Ophthalmology. 1986 May; 93(5):675-80. PMID: 3014416.
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    228. Gamel JW, Greenberg RA, McLean IW, Seddon JM, Albert DM, Naids RE, Folberg R, Donoso LA. A clinically useful method for combining gross and microscopic measurements to select high-risk patients after enucleation for ciliochoroidal melanoma. Cancer. 1986 Apr 01; 57(7):1341-4. PMID: 2418937.
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    229. Seddon JM, Polivogianis L, Gragoudas ES, Hsieh CC, Egan KM. Enucleation vs cobalt 60 irradiation of melanomas. Arch Ophthalmol. 1986 Feb; 104(2):175-6. PMID: 3947285.
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    230. Seddon JM, Gragoudas E, Albert D, Hsieh CC, Polivogianis L, Egan K. Echographic and histologic tumor height measurements in uveal melanoma. Am J Ophthalmol. 1986 Jan 15; 101(1):126-8. PMID: 3942170.
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    231. Gragoudas ES, Seddon JM. Management of choroidal melanomas. Int Ophthalmol Clin. 1986; 26(2):145-58. PMID: 3011694.
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    232. Riedel KG, Svitra PP, Seddon JM, Albert DM, Gragoudas ES, Koehler AM, Coleman DJ, Torpey J, Lizzi FL, Driller J. Proton beam irradiation and hyperthermia. Effects on experimental choroidal melanoma. Arch Ophthalmol. 1985 Dec; 103(12):1862-9. PMID: 3000327.
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    233. Fournier GA, Saulenas AM, Seddon JM, Goitein M, Albert DM, Polivogianis L, Gragoudas E. The effects of pre-enucleation irradiation on the development of metastases from intraocular Greene melanoma in hamsters. Am J Ophthalmol. 1985 Nov 15; 100(5):669-77. PMID: 4061547.
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    234. Weinhaus RS, Seddon JM, Albert DM, Gragoudas ES, Robinson N. Prognostic factor study of survival after enucleation for juxtapapillary melanomas. Arch Ophthalmol. 1985 Nov; 103(11):1673-7. PMID: 4062633.
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    235. Seddon JM, Savory L, Scott-Conner C. Cryptorchidism: the role of medical education in diagnosis. South Med J. 1985 Oct; 78(10):1201-4. PMID: 2864743.
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    236. Pascal SG, Saulenas AM, Fournier GA, Seddon JM, Hatfield RM, Albert DM. An investigation into the association between liver damage and metastatic uveal melanoma. Am J Ophthalmol. 1985 Sep 15; 100(3):448-53. PMID: 4037035.
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    237. Gamel JW, McLean I, Greenberg RA, Naids RM, Folberg R, Donoso LA, Seddon JM, Albert DM. Objective assessment of the malignant potential of intraocular melanomas with standard microslides stained with hematoxylin-eosin. Hum Pathol. 1985 Jul; 16(7):689-92. PMID: 2408986.
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    238. Seddon JM, Gragoudas ES, Albert DM, Hsieh CC, Polivogianis L, Friedenberg GR. Comparison of survival rates for patients with uveal melanoma after treatment with proton beam irradiation or enucleation. Am J Ophthalmol. 1985 Mar 15; 99(3):282-90. PMID: 2983558.
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    239. Gragoudas ES, Seddon J, Goitein M, Verhey L, Munzenrider J, Urie M, Suit HD, Blitzer P, Koehler A. Current results of proton beam irradiation of uveal melanomas. Ophthalmology. 1985 Feb; 92(2):284-91. PMID: 2984625.
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    240. Gragoudas ES, Goitein M, Seddon J, Verhey L, Munzenrider J, Urie M, Suit HD, Blitzer P, Johnson KN, Koehler A. Preliminary results of proton beam irradiation of macular and paramacular melanomas. Br J Ophthalmol. 1984 Jul; 68(7):479-85. PMID: 6329261.
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    241. Albert DM, McGhee CN, Seddon JM, Weichselbaum RR. Development of additional primary tumors after 62 years in the first patient with retinoblastoma cured by radiation therapy. Am J Ophthalmol. 1984 Feb; 97(2):189-96. PMID: 6696029.
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    242. Fournier GA, Albert DM, Arrigg CA, Cohen AM, Lamping KA, Seddon JM. Resection of solitary metastasis. Approach to palliative treatment of hepatic involvement with choroidal melanoma. Arch Ophthalmol. 1984 Jan; 102(1):80-2. PMID: 6200095.
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    243. Lavin PT, Albert DM, Seddon JM. A deficit survival analysis to assess the natural history of uveal melanoma. J Chronic Dis. 1984; 37(6):481-7. PMID: 6725501.
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    244. Seddon JM, Albert DM, Lavin PT, Robinson N. A prognostic factor study of disease-free interval and survival following enucleation for uveal melanoma. Arch Ophthalmol. 1983 Dec; 101(12):1894-9. PMID: 6651594.
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    245. Seddon JM, Gragoudas ES, Albert DM. Ciliary body and choroidal melanomas treated by proton beam irradiation. Histopathologic study of eyes. Arch Ophthalmol. 1983 Sep; 101(9):1402-8. PMID: 6311146.
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    246. Seddon JM, Schwartz B, Flowerdew G. Case-control study of ocular hypertension. Arch Ophthalmol. 1983 Jun; 101(6):891-4. PMID: 6860199.
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    247. Seddon JM, MacLaughlin DT, Albert DM, Gragoudas ES, Ference M. Uveal melanomas presenting during pregnancy and the investigation of oestrogen receptors in melanomas. Br J Ophthalmol. 1982 Nov; 66(11):695-704. PMID: 7126514; PMCID: PMC1039903.
    248. Seddon JM, Corwin JM, Weiter JJ, Brisbane JU, Sutula FC. Solitary extramedullary plasmacytoma of the palpebral conjunctiva. Br J Ophthalmol. 1982 Jul; 66(7):450-4. PMID: 7093184; PMCID: PMC1039821.
    249. Kuo PK, Ni C, Seddon JM, Wu BF, Chen YJ. Orbital tumors among Chinese in the Shanghai area. Int Ophthalmol Clin. 1982; 22(1):87-98. PMID: 7061200.
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    250. Schwartz B, Seddon JM. Increased plasma cortisol levels in ocular hypertension. Arch Ophthalmol. 1981 Oct; 99(10):1791-4. PMID: 7295128.
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