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Jiann-Jyh Lai PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentPathology
AddressUMass Chan Medical School
368 Plantation Street
Worcester MA 01605
Phone508-856-7534
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentPathology
    DivisionBasic Pathology


    Collapse Biography 
    Collapse education and training
    National Taiwan University, Taipei, , TaiwanBSZoology
    National Taiwan University, Taipei, , TaiwanMSImmunology
    University of Rochester, Rochester, NY, United StatesPHDPathology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Stolarski AE, Lai JJ, Kim J, Rock KL, Remick D. GENETIC ABLATION OF THE C-TYPE LECTIN RECEPTOR CLEC2D INCREASES PERITONITIS MORTALITY, INFLAMMATION AND PHYSIOLOGY WITHOUT DIMINISHING ORGAN INJURY. Shock. 2024 Jun 11. PMID: 38888567.
      Citations:    
    2. Altuwaijri S, Chuang KH, Lai KP, Lai JJ, Lin HY, Young FM, Bottaro A, Tsai MY, Zeng WP, Chang HC, Yeh S, Chang C. Corrigendum to: "Susceptibility to Autoimmunity and B Cell Resistance to Apoptosis in Mice Lacking Androgen Receptor in B Cells". Endocrinology. 2020 09 01; 161(9). PMID: 32822479.
      Citations:    Fields:    
    3. Lai JJ, Cruz FM, Rock KL. Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury. Immunity. 2020 01 14; 52(1):123-135.e6. PMID: 31859049.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    4. Lai KP, Lai JJ, Chang P, Altuwaijri S, Hsu JW, Chuang KH, Shyr CR, Yeh S, Chang C. Targeting thymic epithelia AR enhances T-cell reconstitution and bone marrow transplant grafting efficacy. Mol Endocrinol. 2013 Jan; 27(1):25-37. PMID: 23250486.
      Citations: 25     Fields:    Translation:AnimalsCells
    5. Lai JJ, Lai KP, Zeng W, Chuang KH, Altuwaijri S, Chang C. Androgen receptor influences on body defense system via modulation of innate and adaptive immune systems: lessons from conditional AR knockout mice. Am J Pathol. 2012 Nov; 181(5):1504-12. PMID: 22959669.
      Citations: 82     Fields:    Translation:AnimalsCells
    6. Rock KL, Kataoka H, Lai JJ. Uric acid as a danger signal in gout and its comorbidities. Nat Rev Rheumatol. 2013 Jan; 9(1):13-23. PMID: 22945591.
      Citations: 159     Fields:    Translation:HumansCells
    7. Lai JJ, Chang P, Lai KP, Chen L, Chang C. The role of androgen and androgen receptor in skin-related disorders. Arch Dermatol Res. 2012 Sep; 304(7):499-510. PMID: 22829074.
      Citations: 46     Fields:    Translation:HumansAnimals
    8. Rock KL, Lai JJ, Kono H. Innate and adaptive immune responses to cell death. Immunol Rev. 2011 Sep; 243(1):191-205. PMID: 21884177.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    9. Lai JJ, Lai KP, Chuang KH, Chang P, Yu IC, Lin WJ, Chang C. Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expression. J Clin Invest. 2009 Dec; 119(12):3739-51. PMID: 19907077.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    10. Zeng WP, Chang C, Lai JJ. Immune suppressive activity and lack of T helper differentiation are differentially regulated in natural regulatory T cells. J Immunol. 2009 Sep 15; 183(6):3583-90. PMID: 19710452.
      Citations: 9     Fields:    Translation:AnimalsCells
    11. Chuang KH, Altuwaijri S, Li G, Lai JJ, Chu CY, Lai KP, Lin HY, Hsu JW, Keng P, Wu MC, Chang C. Neutropenia with impaired host defense against microbial infection in mice lacking androgen receptor. J Exp Med. 2009 May 11; 206(5):1181-99. PMID: 19414555.
      Citations: 59     Fields:    Translation:AnimalsCells
    12. Altuwaijri S, Chuang KH, Lai KP, Lai JJ, Lin HY, Young FM, Bottaro A, Tsai MY, Zeng WP, Chang HC, Yeh S, Chang C. Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells. Mol Endocrinol. 2009 Apr; 23(4):444-53. PMID: 19164450.
      Citations: 38     Fields:    Translation:AnimalsCells
    13. Ma WL, Ma CL, Hsu CL, Wu MH, Wu CT, Wu CC, Lai JJ, Jou YS, Chen CW, Yeh S, Chang C. Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma. Gastroenterology. 2008 Sep; 135(3):947-55, 955.e1-5. PMID: 18639551.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    14. Tsai HF, Lai JJ, Chou AH, Wang TF, Wu CS, Hsu PN. Induction of costimulation of human CD4 T cells by tumor necrosis factor-related apoptosis-inducing ligand: possible role in T cell activation in systemic lupus erythematosus. Arthritis Rheum. 2004 Feb; 50(2):629-39. PMID: 14872508.
      Citations: 11     Fields:    Translation:HumansCells
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