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Neal C Brown PHD DVM

TitleProfessor Emeritus
InstitutionUMass Chan Medical School
DepartmentBiochemistry and Molecular Biotechnology
Address55 Lake Avenue North
S7-121
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentBiochemistry and Molecular Biotechnology


    Collapse Biography 
    Collapse education and training
    Cornell University, Ithaca, NY, United StatesDVM
    Yale University, New Haven, CT, United StatesPHDPHARMACOLOGY

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Barnes MH, Butler MM, Wright GE, Brown NC. Antimicrobials targeted to the replication-specific DNA polymerases of gram-positive bacteria: target potential of dnaE. Infect Disord Drug Targets. 2012 Oct; 12(5):327-31. PMID: 23017159.
      Citations: 3     Fields:    Translation:Cells
    2. Dvoskin S, Xu WC, Brown NC, Yanachkov IB, Yanachkova M, Wright GE. A novel agent effective against Clostridium difficile infection. Antimicrob Agents Chemother. 2012 Mar; 56(3):1624-6. PMID: 22203600.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    3. Torti A, Lossani A, Savi L, Focher F, Wright GE, Brown NC, Xu WC. Clostridium difficile DNA polymerase IIIC: basis for activity of antibacterial compounds. Curr Enzym Inhib. 2011 Oct; 7(3):147-153. PMID: 22844265.
      Citations:    
    4. Xu WC, Wright GE, Brown NC, Long ZY, Zhi CX, Dvoskin S, Gambino JJ, Barnes MH, Butler MM. 7-Alkyl-N(2)-substituted-3-deazaguanines. Synthesis, DNA polymerase III inhibition and antibacterial activity. Bioorg Med Chem Lett. 2011 Jul 15; 21(14):4197-202. PMID: 21684746.
      Citations: 10     Fields:    Translation:AnimalsCells
    5. Butler MM, Lamarr WA, Foster KA, Barnes MH, Skow DJ, Lyden PT, Kustigian LM, Zhi C, Brown NC, Wright GE, Bowlin TL. Antibacterial activity and mechanism of action of a novel anilinouracil-fluoroquinolone hybrid compound. Antimicrob Agents Chemother. 2007 Jan; 51(1):119-27. PMID: 17074800.
      Citations: 21     Fields:    Translation:HumansCells
    6. Zhi C, Long ZY, Manikowski A, Comstock J, Xu WC, Brown NC, Tarantino PM, Holm KA, Dix EJ, Wright GE, Barnes MH, Butler MM, Foster KA, LaMarr WA, Bachand B, Bethell R, Cadilhac C, Charron S, Lamothe S, Motorina I, Storer R. Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors. J Med Chem. 2006 Feb 23; 49(4):1455-65. PMID: 16480282.
      Citations: 11     Fields:    Translation:AnimalsCells
    7. Zhi C, Long ZY, Manikowski A, Brown NC, Tarantino PM, Holm K, Dix EJ, Wright GE, Foster KA, Butler MM, LaMarr WA, Skow DJ, Motorina I, Lamothe S, Storer R. Synthesis and antibacterial activity of 3-substituted-6-(3-ethyl-4-methylanilino)uracils. J Med Chem. 2005 Nov 03; 48(22):7063-74. PMID: 16250666.
      Citations: 7     Fields:    Translation:AnimalsCells
    8. Wright GE, Brown NC, Xu WC, Long ZY, Zhi C, Gambino JJ, Barnes MH, Butler MM. Active site directed inhibitors of replication-specific bacterial DNA polymerases. Bioorg Med Chem Lett. 2005 Feb 01; 15(3):729-32. PMID: 15664846.
      Citations: 12     Fields:    Translation:HumansCells
    9. Zhi C, Long ZY, Gambino J, Xu WC, Brown NC, Barnes M, Butler M, LaMarr W, Wright GE. Synthesis of substituted 6-anilinouracils and their inhibition of DNA polymerase IIIC and Gram-positive bacterial growth. J Med Chem. 2003 Jun 19; 46(13):2731-9. PMID: 12801236.
      Citations: 15     Fields:    Translation:Cells
    10. Foster KA, Barnes MH, Stephenson RO, Butler MM, Skow DJ, LaMarr WA, Brown NC. DNA polymerase III of Enterococcus faecalis: expression and characterization of recombinant enzymes encoded by the polC and dnaE genes. Protein Expr Purif. 2003 Jan; 27(1):90-7. PMID: 12509989.
      Citations: 5     Fields:    Translation:Cells
    11. Barnes MH, Miller SD, Brown NC. DNA polymerases of low-GC gram-positive eubacteria: identification of the replication-specific enzyme encoded by dnaE. J Bacteriol. 2002 Jul; 184(14):3834-8. PMID: 12081953.
      Citations: 5     Fields:    Translation:Cells
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