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David J McNally PhD

TitleAssistant Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentMedicine
AddressMassBiologics
1240 Innovation Parkway
Fall River MA 02720
Phone617-474-4060
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMedicine
    DivisionMassachusetts Biological Laboratory


    Collapse Biography 
    Collapse education and training
    University of Sheffield, Sheffield, , United KingdomBSBiomedical Science
    University of Cambridge, Cambridge, , United KingdomPHDChemical Engineering

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Simpson AJ, McNally DJ, Simpson MJ. NMR spectroscopy in environmental research: from molecular interactions to global processes. Prog Nucl Magn Reson Spectrosc. 2011 May; 58(3-4):97-175. PMID: 21397118.
      View in: PubMed
    2. Pautler BG, Simpson AJ, McNally DJ, Lamoureux SF, Simpson MJ. Arctic permafrost active layer detachments stimulate microbial activity and degradation of soil organic matter. Environ Sci Technol. 2010 Jun 01; 44(11):4076-82. PMID: 20459054.
      View in: PubMed
    3. Nothaft H, Liu X, McNally DJ, Szymanski CM. N-linked protein glycosylation in a bacterial system. Methods Mol Biol. 2010; 600:227-43. PMID: 19882132.
      View in: PubMed
    4. Brisson JR, Vinogradov E, McNally DJ, Khieu NH, Schoenhofen IC, Logan SM, Jarrell H. The application of NMR spectroscopy to functional glycomics. Methods Mol Biol. 2010; 600:155-73. PMID: 19882127.
      View in: PubMed
    5. Nothaft H, Liu X, McNally DJ, Li J, Szymanski CM. Study of free oligosaccharides derived from the bacterial N-glycosylation pathway. Proc Natl Acad Sci U S A. 2009 Sep 01; 106(35):15019-24. PMID: 19706478.
      View in: PubMed
    6. King JD, Poon KKH, Webb NA, Anderson EM, McNally DJ, Brisson JR, Messner P, Garavito RM, Lam JS. The structural basis for catalytic function of GMD and RMD, two closely related enzymes from the GDP-D-rhamnose biosynthesis pathway. FEBS J. 2009 May; 276(10):2686-2700. PMID: 19459932.
      View in: PubMed
    7. Westman EL, McNally DJ, Charchoglyan A, Brewer D, Field RA, Lam JS. Characterization of WbpB, WbpE, and WbpD and reconstitution of a pathway for the biosynthesis of UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid in Pseudomonas aeruginosa. J Biol Chem. 2009 May 01; 284(18):11854-62. PMID: 19282284.
      View in: PubMed
    8. Twine SM, Paul CJ, Vinogradov E, McNally DJ, Brisson JR, Mullen JA, McMullin DR, Jarrell HC, Austin JW, Kelly JF, Logan SM. Flagellar glycosylation in Clostridium botulinum. FEBS J. 2008 Sep; 275(17):4428-44. PMID: 18671733.
      View in: PubMed
    9. McNally DJ, Schoenhofen IC, Houliston RS, Khieu NH, Whitfield DM, Logan SM, Jarrell HC, Brisson JR. CMP-pseudaminic acid is a natural potent inhibitor of PseB, the first enzyme of the pseudaminic acid pathway in Campylobacter jejuni and Helicobacter pylori. ChemMedChem. 2008 Jan; 3(1):55-9. PMID: 17893902.
      View in: PubMed
    10. Miller WL, Matewish MJ, McNally DJ, Ishiyama N, Anderson EM, Brewer D, Brisson JR, Berghuis AM, Lam JS. Flagellin glycosylation in Pseudomonas aeruginosa PAK requires the O-antigen biosynthesis enzyme WbpO. J Biol Chem. 2008 Feb 08; 283(6):3507-18. PMID: 18065759.
      View in: PubMed
    11. McNally DJ, Lamoureux MP, Karlyshev AV, Fiori LM, Li J, Thacker G, Coleman RA, Khieu NH, Wren BW, Brisson JR, Jarrell HC, Szymanski CM. Commonality and biosynthesis of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni. J Biol Chem. 2007 Sep 28; 282(39):28566-76. PMID: 17675288.
      View in: PubMed
    12. Westman EL, McNally DJ, Rejzek M, Miller WL, Kannathasan VS, Preston A, Maskell DJ, Field RA, Brisson JR, Lam JS. Identification and biochemical characterization of two novel UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerases from respiratory pathogens. Biochem J. 2007 Jul 01; 405(1):123-30. PMID: 17346239.
      View in: PubMed
    13. McNally DJ, Aubry AJ, Hui JP, Khieu NH, Whitfield D, Ewing CP, Guerry P, Brisson JR, Logan SM, Soo EC. Targeted metabolomics analysis of Campylobacter coli VC167 reveals legionaminic acid derivatives as novel flagellar glycans. J Biol Chem. 2007 May 11; 282(19):14463-75. PMID: 17371878.
      View in: PubMed
    14. McNally DJ, Schoenhofen IC, Mulrooney EF, Whitfield DM, Vinogradov E, Lam JS, Logan SM, Brisson JR. Identification of labile UDP-ketosugars in Helicobacter pylori, Campylobacter jejuni and Pseudomonas aeruginosa: key metabolites used to make glycan virulence factors. Chembiochem. 2006 Dec; 7(12):1865-8. PMID: 17031886.
      View in: PubMed
    15. Liu X, McNally DJ, Nothaft H, Szymanski CM, Brisson JR, Li J. Mass spectrometry-based glycomics strategy for exploring N-linked glycosylation in eukaryotes and bacteria. Anal Chem. 2006 Sep 01; 78(17):6081-7. PMID: 16944887.
      View in: PubMed
    16. McNally DJ, Jarrell HC, Khieu NH, Li J, Vinogradov E, Whitfield DM, Szymanski CM, Brisson JR. The HS:19 serostrain of Campylobacter jejuni has a hyaluronic acid-type capsular polysaccharide with a nonstoichiometric sorbose branch and O-methyl phosphoramidate group. FEBS J. 2006 Sep; 273(17):3975-89. PMID: 16879613.
      View in: PubMed
    17. Schoenhofen IC, McNally DJ, Brisson JR, Logan SM. Elucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction. Glycobiology. 2006 Sep; 16(9):8C-14C. PMID: 16751642.
      View in: PubMed
    18. McNally DJ, Hui JP, Aubry AJ, Mui KK, Guerry P, Brisson JR, Logan SM, Soo EC. Functional characterization of the flagellar glycosylation locus in Campylobacter jejuni 81-176 using a focused metabolomics approach. J Biol Chem. 2006 Jul 07; 281(27):18489-98. PMID: 16684771.
      View in: PubMed
    19. Rémus-Borel W, Shallow N, McNally DJ, Labbé C, Bélanger RR. High-speed counter-current chromatography for the study of defense metabolites in wheat. Characterization of 5,6-O-methyl trans-aconitic acid. J Chromatogr A. 2006 Jul 21; 1121(2):200-8. PMID: 16650851.
      View in: PubMed
    20. Schoenhofen IC, McNally DJ, Vinogradov E, Whitfield D, Young NM, Dick S, Wakarchuk WW, Brisson JR, Logan SM. Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways. J Biol Chem. 2006 Jan 13; 281(2):723-32. PMID: 16286454.
      View in: PubMed
    21. McNally DJ, Jarrell HC, Li J, Khieu NH, Vinogradov E, Szymanski CM, Brisson JR. The HS:1 serostrain of Campylobacter jejuni has a complex teichoic acid-like capsular polysaccharide with nonstoichiometric fructofuranose branches and O-methyl phosphoramidate groups. FEBS J. 2005 Sep; 272(17):4407-22. PMID: 16128810.
      View in: PubMed
    22. Mulrooney EF, Poon KK, McNally DJ, Brisson JR, Lam JS. Biosynthesis of UDP-N-acetyl-L-fucosamine, a precursor to the biosynthesis of lipopolysaccharide in Pseudomonas aeruginosa serotype O11. J Biol Chem. 2005 May 20; 280(20):19535-42. PMID: 15778500.
      View in: PubMed
    23. Fofana B, Benhamou N, McNally DJ, Labbé C, Séguin A, Bélanger RR. Suppression of induced resistance in cucumber through disruption of the flavonoid pathway. Phytopathology. 2005 Jan; 95(1):114-23. PMID: 18943844.
      View in: PubMed
    24. Rodrigues FA, McNally DJ, Datnoff LE, Jones JB, Labbé C, Benhamou N, Menzies JG, Bélanger RR. Silicon enhances the accumulation of diterpenoid phytoalexins in rice: a potential mechanism for blast resistance. Phytopathology. 2004 Feb; 94(2):177-83. PMID: 18943541.
      View in: PubMed
    25. McNally DJ, Wurms KV, Labbé C, Quideau S, Bélanger RR. Complex C-glycosyl flavonoid phytoalexins from Cucumis sativus. J Nat Prod. 2003 Sep; 66(9):1280-3. PMID: 14510618.
      View in: PubMed
    26. Cheng Y, McNally DJ, Labbé C, Voyer N, Belzile F, Bélanger RR. Insertional mutagenesis of a fungal biocontrol agent led to discovery of a rare cellobiose lipid with antifungal activity. Appl Environ Microbiol. 2003 May; 69(5):2595-602. PMID: 12732526.
      View in: PubMed
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