"Dasatinib" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrimidine and thiazole derived ANTINEOPLASTIC AGENT and PROTEIN KINASE INHIBITOR of BCR-ABL KINASE. It is used in the treatment of patients with CHRONIC MYELOID LEUKEMIA who are resistant or intolerant to IMATINIB.
| Descriptor ID |
D000069439
|
| MeSH Number(s) |
D02.886.675.184 D03.383.129.708.198 D03.383.742.148
|
| Concept/Terms |
Dasatinib- Dasatinib
- N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide
BMS 354825- BMS 354825
- 354825, BMS
- BMS354825
- BMS-354825
|
Below are MeSH descriptors whose meaning is more general than "Dasatinib".
Below are MeSH descriptors whose meaning is more specific than "Dasatinib".
This graph shows the total number of publications written about "Dasatinib" by people in this website by year, and whether "Dasatinib" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Dasatinib" by people in Profiles.
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Laukkanen S, Veloso A, Yan C, Oksa L, Alpert EJ, Do D, Hyv?rinen N, McCarthy K, Adhikari A, Yang Q, Iyer S, Garcia SP, Pello A, Ruokoranta T, Moisio S, Adhikari S, Yoder JA, Gallagher K, Whelton L, Allen JR, Jin AH, Loontiens S, Hein?niemi M, Kelliher M, Heckman CA, Lohi O, Langenau DM. Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia. Blood. 2022 10 27; 140(17):1891-1906.
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Pandey D, Shepro DS. Thymic cancer in lynch syndrome: an unusual association. BMJ Case Rep. 2020 Apr 08; 13(4).
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Mishra AK, Sahu KK, Kaul S, Lal A. Dasatinib induced pleuro-pericardial effusion. Acta Biomed. 2020 03 19; 91(1):142-143.
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Katsumata R, Ishigaki S, Katsuno M, Kawai K, Sone J, Huang Z, Adachi H, Tanaka F, Urano F, Sobue G. c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis. PLoS One. 2012; 7(9):e46185.
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Peng C, Chen Y, Li D, Li S. Role of Pten in leukemia stem cells. Oncotarget. 2010 Jun; 1(2):156-160.