"Simeprevir" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Oral HCV-PROTEASE INHIBITOR effective against hepatitis C virus (HCV) serine protease NS3/4A. It is used in the treatment of chronic hepatitis C (Antivirals) genotype 1 infection in adults with compensated liver disease, including CIRRHOSIS.
Descriptor ID |
D000069616
|
MeSH Number(s) |
D02.886.590.700.700 D03.633.300.819
|
Concept/Terms |
Simeprevir- Simeprevir
- N-(17-(2-(4-isopropylthiazole-2-yl)-7-methoxy-8-methylquinolin-4-yloxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo(13.3.0.04,6)octadec-7-ene-4-carbonyl)(cyclopropyl)sulfonamide
TMC 435350- TMC 435350
- 435350, TMC
- TMC435350
- TMC-435350
TMC 435- TMC 435
- 435, TMC
- TMC435
- TMC-435
|
Below are MeSH descriptors whose meaning is more general than "Simeprevir".
Below are MeSH descriptors whose meaning is more specific than "Simeprevir".
This graph shows the total number of publications written about "Simeprevir" by people in this website by year, and whether "Simeprevir" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
---|
2015 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Simeprevir" by people in Profiles.
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Theodoropoulos N, Whitson BA, Martin SI, Pouch S, Pope-Harman A. Successful treatment of donor-derived hepatitis C infection in a lung transplant recipient. Transpl Infect Dis. 2017 Apr; 19(2).
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Lin MV, Sise ME, Pavlakis M, Amundsen BM, Chute D, Rutherford AE, Chung RT, Curry MP, Hanifi JM, Gabardi S, Chandraker A, Heher EC, Elias N, Riella LV. Efficacy and Safety of Direct Acting Antivirals in Kidney Transplant Recipients with Chronic Hepatitis C Virus Infection. PLoS One. 2016; 11(7):e0158431.
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Punzalan CS, Barry C, Zacharias I, Rodrigues J, Mehta S, Bozorgzadeh A, Barnard GF. Sofosbuvir plus simeprevir treatment of recurrent genotype 1 hepatitis C after liver transplant. Clin Transplant. 2015 Dec; 29(12):1105-11.