Sildenafil Citrate

"Sildenafil Citrate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A PHOSPHODIESTERASE TYPE-5 INHIBITOR; VASODILATOR AGENT and UROLOGICAL AGENT that is used in the treatment of ERECTILE DYSFUNCTION and PRIMARY PULMONARY HYPERTENSION.

Descriptor ID	D000068677
MeSH Number(s)	D02.065.884.675 D02.886.590.700.675 D03.383.606.854 D03.633.100.759.824
Concept/Terms	Sildenafil Citrate Sildenafil Citrate Citrate, Sildenafil 1-((3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate NCX-911 NCX-911 NCX 911 NCX911 Revatio Revatio Sildenafil Sildenafil UK 92480-10 UK 92480-10 UK 92480 10 UK 9248010 UK-92,480-10 UK 92,480 10 Homosildenafil Homosildenafil Hydroxyhomosildenafil Hydroxyhomosildenafil Viagra Viagra Acetildenafil Acetildenafil Sildenafil Lactate Sildenafil Lactate Lactate, Sildenafil Sildenafil Nitrate Sildenafil Nitrate Nitrate, Sildenafil Desmethyl Sildenafil Desmethyl Sildenafil Sildenafil, Desmethyl Desmethylsildenafil

Below are MeSH descriptors whose meaning is more general than "Sildenafil Citrate".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amides [D02.065]
Sulfonamides [D02.065.884]
Sildenafil Citrate [D02.065.884.675]
Sulfur Compounds [D02.886]
Sulfones [D02.886.590]
Sulfonamides [D02.886.590.700]
Sildenafil Citrate [D02.886.590.700.675]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Piperazines [D03.383.606]
Sildenafil Citrate [D03.383.606.854]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Sildenafil Citrate [D03.633.100.759.824]

Below are MeSH descriptors whose meaning is related to "Sildenafil Citrate".

Below are MeSH descriptors whose meaning is more specific than "Sildenafil Citrate".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Sildenafil Citrate" by people in this website by year, and whether "Sildenafil Citrate" was a major or minor topic of these publications.

Bar chart showing 14 publications over 13 distinct years, with a maximum of 2 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2001	0	1	1
2002	0	1	1
2005	0	1	1
2006	0	1	1
2007	0	1	1
2009	0	2	2
2011	0	1	1
2012	0	1	1
2013	0	1	1
2018	1	0	1
2019	1	0	1
2021	0	1	1

Below are the most recent publications written about "Sildenafil Citrate" by people in Profiles.

Calamaras TD, Pande S, Baumgartner RA, Kim SK, McCarthy JC, Martin GL, Tam K, McLaughlin AL, Wang GR, Aronovitz MJ, Lin W, Aguirre JI, Baca P, Liu P, Richards DA, Davis RJ, Karas RH, Jaffe IZ, Blanton RM. MLK3 mediates impact of PKG1a on cardiac function and controls blood pressure through separate mechanisms. JCI Insight. 2021 09 22; 6(18).

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Behr J, Kolb M, Song JW, Luppi F, Schinzel B, Stowasser S, Quaresma M, Martinez FJ. Nintedanib and Sildenafil in Patients with Idiopathic Pulmonary Fibrosis and Right Heart Dysfunction. A Prespecified Subgroup Analysis of a Double-Blind Randomized Clinical Trial (INSTAGE). Am J Respir Crit Care Med. 2019 12 15; 200(12):1505-1512.

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Kolb M, Raghu G, Wells AU, Behr J, Richeldi L, Schinzel B, Quaresma M, Stowasser S, Martinez FJ. Nintedanib plus Sildenafil in Patients with Idiopathic Pulmonary Fibrosis. N Engl J Med. 2018 11 01; 379(18):1722-1731.

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Han MK, Bach DS, Hagan PG, Yow E, Flaherty KR, Toews GB, Anstrom KJ, Martinez FJ. Sildenafil preserves exercise capacity in patients with idiopathic pulmonary fibrosis and right-sided ventricular dysfunction. Chest. 2013 Jun; 143(6):1699-1708.

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Hanisch LJ, Bryan CJ, James JL, Pisansky TM, Corbett TB, Parliament MB, Stewart CE, Hartford AC, Sandler H, Berk LB, Kachnic L, Bruner DW. Impact of sildenafil on marital and sexual adjustment in patients and their wives after radiotherapy and short-term androgen suppression for prostate cancer: analysis of RTOG 0215. Support Care Cancer. 2012 Nov; 20(11):2845-50.

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Montaser-Kouhsari L, Payandemehr B, Gholipour T, Ziai P, Nabavizadeh P, Ghasemi A, Bahremand A, Ghasemi M, Dehpour AR. A role for opioid system in the proconvulsant effects of sildenafil on the pentylenetetrazole-induced clonic seizure in mice. Seizure. 2011 Jun; 20(5):409-13.

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Silver B, McCarthy S, Lu M, Mitsias P, Russman AN, Katramados A, Morris DC, Lewandowski CA, Chopp M. Sildenafil treatment of subacute ischemic stroke: a safety study at 25-mg daily for 2 weeks. J Stroke Cerebrovasc Dis. 2009 Sep-Oct; 18(5):381-3.

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Ebrahimi F, Shafaroodi H, Asadi S, Nezami BG, Ghasemi M, Rahimpour S, Hashemi M, Doostar Y, Dehpour AR. Sildenafil decreased cardiac cell apoptosis in diabetic mice: reduction of oxidative stress as a possible mechanism. Can J Physiol Pharmacol. 2009 Jul; 87(7):556-64.

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McCullough AR, Levine LA, Padma-Nathan H. Return of nocturnal erections and erectile function after bilateral nerve-sparing radical prostatectomy in men treated nightly with sildenafil citrate: subanalysis of a longitudinal randomized double-blind placebo-controlled trial. J Sex Med. 2008 Feb; 5(2):476-84.

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Fell CD, Martinez FJ. The impact of pulmonary arterial hypertension on idiopathic pulmonary fibrosis. Chest. 2007 Mar; 131(3):641-3.

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