Tenofovir

"Tenofovir" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.

Descriptor ID	D000068698
MeSH Number(s)	D02.705.429.906 D03.633.100.759.138.881
Concept/Terms	Tenofovir Tenofovir 9-(2-Phosphonylmethoxypropyl)adenine 9-PMPA (tenofovir) 9-(2-Phosphonomethoxypropyl)adenine 9-(2-Phosphonylmethoxypropyl)adenine, (S)-isomer 9-(2-Phosphonylmethoxypropyl)adenine, (S)-isomer 9-(2-Phosphonylmethoxypropyl)adenine, (+-)-isomer 9-(2-Phosphonylmethoxypropyl)adenine, (+-)-isomer Tenofovir Disoproxil Fumarate Tenofovir Disoproxil Fumarate Disoproxil Fumarate, Tenofovir Fumarate, Tenofovir Disoproxil Tenofovir Disoproxil Tenofovir Disoproxil Disoproxil, Tenofovir 9-(2-Phosphonylmethoxypropyl)adenine, (R)-isomer - T357098 9-(2-Phosphonylmethoxypropyl)adenine, (R)-isomer - T357098 (R)-9-(2-phosphonylmethoxypropyl)adenine Viread Viread

Below are MeSH descriptors whose meaning is more general than "Tenofovir".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Organophosphorus Compounds [D02.705]
Organophosphonates [D02.705.429]
Tenofovir [D02.705.429.906]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Adenine [D03.633.100.759.138]
Tenofovir [D03.633.100.759.138.881]

Below are MeSH descriptors whose meaning is related to "Tenofovir".

Below are MeSH descriptors whose meaning is more specific than "Tenofovir".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tenofovir" by people in this website by year, and whether "Tenofovir" was a major or minor topic of these publications.

Bar chart showing 1 publications over 1 distinct years, with a maximum of 1 publications in 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2023	0	1	1

Below are the most recent publications written about "Tenofovir" by people in Profiles.

Singh S. Medication safety in chronic kidney disease. Curr Opin Nephrol Hypertens. 2023 09 01; 32(5):434-438.

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Eshleman SH, Fogel JM, Piwowar-Manning E, Chau G, Cummings V, Agyei Y, Richardson P, Sullivan P, Haines CD, Bushman LR, Petropoulos C, Persaud D, Kofron R, Hendrix CW, Anderson PL, Farrior J, Mellors J, Adeyeye A, Rinehart A, St Clair M, Ford S, Rooney JF, Mathew CA, Hunidzarira P, Spooner E, Mpendo J, Nair G, Cohen MS, Hughes JP, Hosseinipour M, Hanscom B, Delany-Moretlwe S, Marzinke MA. Characterization of Human Immunodeficiency Virus (HIV) Infections in Women Who Received Injectable Cabotegravir or Tenofovir Disoproxil Fumarate/Emtricitabine for HIV Prevention: HPTN 084. J Infect Dis. 2022 05 16; 225(10):1741-1749.

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Fogel JM, Sivay MV, Cummings V, Wilson EA, Hart S, Gamble T, Laeyendecker O, Fernandez RE, Del Rio C, Batey DS, Mayer KH, Farley JE, McKinstry L, Hughes JP, Remien RH, Beyrer C, Eshleman SH. HIV drug resistance in a cohort of HIV-infected MSM in the United States. AIDS. 2020 01 01; 34(1):91-101.

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Holtz TH, Chitwarakorn A, Hughes JP, Curlin ME, Varangrat A, Li M, Amico KR, Mock PA, Grant RM. HPTN 067/ADAPT: Correlates of Sex-Related Pre-exposure Prophylaxis Adherence, Thai Men Who Have Sex With Men, and Transgender Women, 2012-2013. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):e18-e26.

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Velloza J, Bacchetti P, Hendrix CW, Murnane P, Hughes JP, Li M, Curlin ME, Holtz TH, Mannheimer S, Marzinke MA, Amico KR, Liu A, Piwowar-Manning E, Eshleman SH, Dye BJ, Gandhi M, Grant RM. Short- and Long-Term Pharmacologic Measures of HIV Pre-exposure Prophylaxis Use Among High-Risk Men Who Have Sex With Men in HPTN 067/ADAPT. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):149-158.

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Ojeda VD, Amico KR, Hughes JP, Wilson E, Li M, Holtz TH, Chitwarakorn A, Grant RM, Dye BJ, Bekker LG, Mannheimer S, Marzinke M, Hendrix CW. Low Disclosure of PrEP Nonadherence and HIV-Risk Behaviors Associated With Poor HIV PrEP Adherence in the HPTN 067/ADAPT Study. J Acquir Immune Defic Syndr. 2019 09 01; 82(1):34-40.

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Chai PR, Pereira LM, Jambaulikar GD, Carrico AW, O'Cleirigh C, Mayer KH, Boyer EW. Short Communication: Bioequivalence of Tenofovir Component of Tenofovir/Rilpivirine/Emtricitabine in Digital Pills. AIDS Res Hum Retroviruses. 2019 04; 35(4):361-363.

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Grant RM, Mannheimer S, Hughes JP, Hirsch-Moverman Y, Loquere A, Chitwarakorn A, Curlin ME, Li M, Amico KR, Hendrix CW, Anderson PL, Dye BJ, Marzinke MA, Piwowar-Manning E, McKinstry L, Elharrar V, Stirratt M, Rooney JF, Eshleman SH, McNicholl JM, van Griensven F, Holtz TH. Daily and Nondaily Oral Preexposure Prophylaxis in Men and Transgender Women Who Have Sex With Men: The Human Immunodeficiency Virus Prevention Trials Network 067/ADAPT Study. Clin Infect Dis. 2018 05 17; 66(11):1712-1721.

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Figueroa DB, Tillotson J, Li M, Piwowar-Manning E, Hendrix CW, Holtz TH, Bokoch K, Bekker LG, van Griensven F, Mannheimer S, Hughes JP, Grant RM, Bumpus NN. Discovery of genetic variants of the kinases that activate tenofovir among individuals in the United States, Thailand, and South Africa: HPTN067. PLoS One. 2018; 13(4):e0195764.

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Mitchell KM, Dimitrov D, Hughes JP, Xia F, Donnell D, Amico KR, Bokoch K, Chitwarakorn A, Bekker LG, Holtz TH, Mannheimer S, Grant RM, Boily MC. In what circumstances could nondaily preexposure prophylaxis for HIV substantially reduce program costs? AIDS. 2018 03 27; 32(6):809-818.

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