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CD48 Antigen

"CD48 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A 40-45 KDa GPI-linked protein in the SLAM family that consists of two IMMUNOGLOBULIN C2-SET DOMAINS. It is expressed on the surface of a variety of cells with immune functions, including THYMOCYTES; mature B-LYMPHOCYTES and T-LYMPHOCYTES; NATURAL KILLER CELLS; DENDRITIC CELLS; MAST CELLS; and EOSINOPHILS. It binds to CD2 and 2B4 (CD244) receptors to activate and modulate the immunologic response.

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