Bone Marrow Stromal Antigen 2
"Bone Marrow Stromal Antigen 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GPI-linked membrane glycoprotein and antiviral factor that functions as a homodimer. It is induced by INTERFERON-GAMMA and blocks the release of enveloped mammalian viruses by directly tethering nascent VIRAL PARTICLES to the membranes of infected cells.
| Descriptor ID |
D000074010
|
| MeSH Number(s) |
D12.776.395.550.448.150 D12.776.543.484.500.150 D12.776.543.550.418.150
|
| Concept/Terms |
Bone Marrow Stromal Antigen 2- Bone Marrow Stromal Antigen 2
- Bone Marrow Stromal Cell Antigen 2
- Antigen, CD317
- Antigens, CD317
- CD317 Antigens
- Tetherin
- CD317 Antigen
|
Below are MeSH descriptors whose meaning is more general than "Bone Marrow Stromal Antigen 2".
Below are MeSH descriptors whose meaning is more specific than "Bone Marrow Stromal Antigen 2".
This graph shows the total number of publications written about "Bone Marrow Stromal Antigen 2" by people in this website by year, and whether "Bone Marrow Stromal Antigen 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bone Marrow Stromal Antigen 2" by people in Profiles.
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Serra-Moreno R, Zimmermann K, Stern LJ, Evans DT. Tetherin/BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis. PLoS Pathog. 2013; 9(7):e1003487.
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Weissenhorn W, Miguet N, Aschman N, Renesto P, Usami Y, Gottlinger HG. Structural basis of tetherin function. Curr HIV Res. 2012 Jun; 10(4):298-306.
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Hinz A, Miguet N, Natrajan G, Usami Y, Yamanaka H, Renesto P, Hartlieb B, McCarthy AA, Simorre JP, G?ttlinger H, Weissenhorn W. Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain. Cell Host Microbe. 2010 Apr 22; 7(4):314-323.
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Strebel K, Luban J, Jeang KT. Human cellular restriction factors that target HIV-1 replication. BMC Med. 2009 Sep 16; 7:48.
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Mangeat B, Gers-Huber G, Lehmann M, Zufferey M, Luban J, Piguet V. HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation. PLoS Pathog. 2009 Sep; 5(9):e1000574.