Single Molecule Imaging

"Single Molecule Imaging" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

High resolution imaging techniques that allow visualization of individual molecules of proteins, lipids, or nucleic acids within cells or tissues.

Descriptor ID	D000072760
MeSH Number(s)	E01.370.350.515.899 E01.370.350.557.750 E05.595.899 E05.601.555.500
Concept/Terms	Single Molecule Imaging Single Molecule Imaging Imaging, Single Molecule Single Molecule Spectroscopy Single Molecule Spectroscopy Spectroscopy, Single Molecule Single Molecule Microscopy Single Molecule Microscopy Microscopy, Single Molecule

Below are MeSH descriptors whose meaning is more general than "Single Molecule Imaging".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Diagnosis [E01]
Diagnostic Techniques and Procedures [E01.370]
Diagnostic Imaging [E01.370.350]
Microscopy [E01.370.350.515]
Single Molecule Imaging [E01.370.350.515.899]
Molecular Imaging [E01.370.350.557]
Single Molecule Imaging [E01.370.350.557.750]
Investigative Techniques [E05]
Microscopy [E05.595]
Single Molecule Imaging [E05.595.899]
Molecular Probe Techniques [E05.601]
Molecular Imaging [E05.601.555]
Single Molecule Imaging [E05.601.555.500]

Below are MeSH descriptors whose meaning is related to "Single Molecule Imaging".

Below are MeSH descriptors whose meaning is more specific than "Single Molecule Imaging".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Single Molecule Imaging" by people in this website by year, and whether "Single Molecule Imaging" was a major or minor topic of these publications.

Bar chart showing 16 publications over 7 distinct years, with a maximum of 4 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2016	2	1	3
2017	1	1	2
2018	2	2	4
2019	3	0	3
2020	0	2	2
2021	1	0	1
2022	1	0	1

Below are the most recent publications written about "Single Molecule Imaging" by people in Profiles.

Korostelev AA. The Structural Dynamics of Translation. Annu Rev Biochem. 2022 06 21; 91:245-267.

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Lee WTC, Yin Y, Morten MJ, Tonzi P, Gwo PP, Odermatt DC, Modesti M, Cantor SB, Gari K, Huang TT, Rothenberg E. Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling. Nat Commun. 2021 05 05; 12(1):2525.

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Jolly SM, Gainetdinov I, Jouravleva K, Zhang H, Strittmatter L, Bailey SM, Hendricks GM, Dhabaria A, Ueberheide B, Zamore PD. Thermus thermophilus Argonaute Functions in the Completion of DNA Replication. Cell. 2020 09 17; 182(6):1545-1559.e18.

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Wolak C, Ma HJ, Soubry N, Sandler SJ, Reyes-Lamothe R, Keck JL. Interaction with single-stranded DNA-binding protein localizes ribonuclease HI to DNA replication forks and facilitates R-loop removal. Mol Microbiol. 2020 09; 114(3):495-509.

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Lu M, Ma X, Castillo-Menendez LR, Gorman J, Alsahafi N, Ermel U, Terry DS, Chambers M, Peng D, Zhang B, Zhou T, Reichard N, Wang K, Grover JR, Carman BP, Gardner MR, Niki?-Spiegel I, Sugawara A, Arthos J, Lemke EA, Smith AB, Farzan M, Abrams C, Munro JB, McDermott AB, Finzi A, Kwong PD, Blanchard SC, Sodroski JG, Mothes W. Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET. Nature. 2019 04; 568(7752):415-419.

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Smith CS, Jouravleva K, Huisman M, Jolly SM, Zamore PD, Grunwald D. An automated Bayesian pipeline for rapid analysis of single-molecule binding data. Nat Commun. 2019 01 17; 10(1):272.

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Lari A, Farzam F, Bensidoun P, Oeffinger M, Zenklusen D, Grunwald D, Montpetit B. Live-Cell Imaging of mRNP-NPC Interactions in Budding Yeast. Methods Mol Biol. 2019; 2038:131-150.

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Vemu A, Szczesna E, Zehr EA, Spector JO, Grigorieff N, Deaconescu AM, Roll-Mecak A. Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation. Science. 2018 08 24; 361(6404).

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Das DK, Govindan R, Niki?-Spiegel I, Krammer F, Lemke EA, Munro JB. Direct Visualization of the Conformational Dynamics of Single Influenza Hemagglutinin Trimers. Cell. 2018 08 09; 174(4):926-937.e12.

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Grant T, Rohou A, Grigorieff N. cisTEM, user-friendly software for single-particle image processing. Elife. 2018 03 07; 7.

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