Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome
"Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
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A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34 amino acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6, and Apc8, have been shown to mediate protein-protein interactions, suggesting that Apc7 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors.
Descriptor ID |
D064195
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MeSH Number(s) |
D08.811.464.938.750.092.992 D12.776.167.024.992
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome".
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This graph shows the total number of publications written about "Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in this website by year, and whether "Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in Profiles.
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Ferguson CJ, Urso O, Bodrug T, Gassaway BM, Watson ER, Prabu JR, Lara-Gonzalez P, Martinez-Chacin RC, Wu DY, Brigatti KW, Puffenberger EG, Taylor CM, Haas-Givler B, Jinks RN, Strauss KA, Desai A, Gabel HW, Gygi SP, Schulman BA, Brown NG, Bonni A. APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain. Mol Cell. 2022 01 06; 82(1):90-105.e13.