"Cdc20 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly conserved proteins that specifically bind to and activate the anaphase-promoting complex-cyclosome, promoting ubiquitination and proteolysis of cell-cycle-regulatory proteins. Cdc20 is essential for anaphase-promoting complex activity, initiation of anaphase, and cyclin proteolysis during mitosis.
Descriptor ID |
D064199
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MeSH Number(s) |
D08.811.464.938.750.092.998 D12.776.167.024.998
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cdc20 Proteins".
Below are MeSH descriptors whose meaning is more specific than "Cdc20 Proteins".
This graph shows the total number of publications written about "Cdc20 Proteins" by people in this website by year, and whether "Cdc20 Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2018 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cdc20 Proteins" by people in Profiles.
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Arsenault HE, Ghizzoni JM, Leech CM, Diers AR, Gesta S, Vishnudas VK, Narain NR, Sarangarajan R, Benanti JA. Ubc1 turnover contributes to the spindle assembly checkpoint in Saccharomyces cerevisiae. G3 (Bethesda). 2021 12 08; 11(12).
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Choppara S, Malonia SK, Sankaran G, Green MR, Santra MK. Degradation of FBXO31 by APC/C is regulated by AKT- and ATM-mediated phosphorylation. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):998-1003.
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Xie Q, Wu Q, Mack SC, Yang K, Kim L, Hubert CG, Flavahan WA, Chu C, Bao S, Rich JN. CDC20 maintains tumor initiating cells. Oncotarget. 2015 May 30; 6(15):13241-54.
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Benanti JA, Toczyski DP. Cdc20, an activator at last. Mol Cell. 2008 Nov 21; 32(4):460-1.
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Rappleye CA, Tagawa A, Lyczak R, Bowerman B, Aroian RV. The anaphase-promoting complex and separin are required for embryonic anterior-posterior axis formation. Dev Cell. 2002 Feb; 2(2):195-206.