Fatty Acid Synthases

"Fatty Acid Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzymes that catalyze the synthesis of FATTY ACIDS from acetyl-CoA and malonyl-CoA derivatives.

Descriptor ID	D064429
MeSH Number(s)	D08.811.277.352.897.387 D08.811.520.241.300.287 D08.811.682.047.820.196.500 D08.811.913.050.134.029.500 D08.811.913.050.170.500
Concept/Terms	Fatty Acid Synthases Fatty Acid Synthases Acid Synthases, Fatty Fatty Acid Synthetases Synthetases, Fatty Acid

Below are MeSH descriptors whose meaning is more general than "Fatty Acid Synthases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Thiolester Hydrolases [D08.811.277.352.897]
Fatty Acid Synthases [D08.811.277.352.897.387]
Lyases [D08.811.520]
Carbon-Oxygen Lyases [D08.811.520.241]
Hydro-Lyases [D08.811.520.241.300]
Fatty Acid Synthases [D08.811.520.241.300.287]
Oxidoreductases [D08.811.682]
Alcohol Oxidoreductases [D08.811.682.047]
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases [D08.811.682.047.820]
3-Oxoacyl-(Acyl-Carrier-Protein) Reductase [D08.811.682.047.820.196]
Fatty Acid Synthases [D08.811.682.047.820.196.500]
Transferases [D08.811.913]
Acyltransferases [D08.811.913.050]
Acetyltransferases [D08.811.913.050.134]
Acyl-Carrier Protein S-Acetyltransferase [D08.811.913.050.134.029]
Fatty Acid Synthases [D08.811.913.050.134.029.500]
Acyl-Carrier Protein S-Malonyltransferase [D08.811.913.050.170]
Fatty Acid Synthases [D08.811.913.050.170.500]

Below are MeSH descriptors whose meaning is more specific than "Fatty Acid Synthases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fatty Acid Synthases" by people in this website by year, and whether "Fatty Acid Synthases" was a major or minor topic of these publications.

Bar chart showing 9 publications over 5 distinct years, with a maximum of 2 publications in 2016 and 2017 and 2018 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	0	1	1
2016	1	1	2
2017	1	1	2
2018	1	1	2
2020	0	2	2

Below are the most recent publications written about "Fatty Acid Synthases" by people in Profiles.

Henriques F, Bedard AH, Guilherme A, Kelly M, Chi J, Zhang P, Lifshitz LM, Bellvé K, Rowland LA, Yenilmez B, Kumar S, Wang Y, Luban J, Weinstein LS, Lin JD, Cohen P, Czech MP. Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis. Cell Rep. 2020 08 04; 32(5):107998.

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Martinez Calejman C, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villén J, Wellen KE, Guertin DA. mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nat Commun. 2020 Jan 29; 11(1):575.

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Wallace M, Green CR, Roberts LS, Lee YM, McCarville JL, Sanchez-Gurmaches J, Meurs N, Gengatharan JM, Hover JD, Phillips SA, Ciaraldi TP, Guertin DA, Cabrales P, Ayres JS, Nomura DK, Loomba R, Metallo CM. Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues. Nat Chem Biol. 2018 11; 14(11):1021-1031.

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Guilherme A, Pedersen DJ, Henriques F, Bedard AH, Henchey E, Kelly M, Morgan DA, Rahmouni K, Czech MP. Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis. Mol Metab. 2018 10; 16:116-125.

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Russo L, Muturi HT, Ghadieh HE, Ghanem SS, Bowman TA, Noh HL, Dagdeviren S, Dogbey GY, Kim JK, Heinrich G, Najjar SM. Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice. Diabetologia. 2017 12; 60(12):2463-2474.

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Guilherme A, Pedersen DJ, Henchey E, Henriques FS, Danai LV, Shen Y, Yenilmez B, Jung D, Kim JK, Lodhi IJ, Semenkovich CF, Czech MP. Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming. Mol Metab. 2017 08; 6(8):781-796.

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Bukong TN, Iracheta-Vellve A, Gyongyosi B, Ambade A, Catalano D, Kodys K, Szabo G. Therapeutic Benefits of Spleen Tyrosine Kinase Inhibitor Administration on Binge Drinking-Induced Alcoholic Liver Injury, Steatosis, and Inflammation in Mice. Alcohol Clin Exp Res. 2016 07; 40(7):1524-30.

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Padilla-Benavides T, Velez-delValle C, Marsch-Moreno M, Castro-Muñozledo F, Kuri-Harcuch W. Lipogenic Enzymes Complexes and Cytoplasmic Lipid Droplet Formation During Adipogenesis. J Cell Biochem. 2016 10; 117(10):2315-26.

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Moore RG, Lange TS, Robinson K, Kim KK, Uzun A, Horan TC, Kawar N, Yano N, Chu SR, Mao Q, Brard L, DePaepe ME, Padbury JF, Arnold LA, Brodsky A, Shen TL, Singh RK. Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model. PLoS One. 2012; 7(4):e34443.

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García A, Ihrig MM, Fry RC, Feng Y, Xu S, Boutin SR, Rogers AB, Muthupalani S, Samson LD, Fox JG. Genetic susceptibility to chronic hepatitis is inherited codominantly in Helicobacter hepaticus-infected AB6F1 and B6AF1 hybrid male mice, and progression to hepatocellular carcinoma is linked to hepatic expression of lipogenic genes and immune function-associated networks. Infect Immun. 2008 May; 76(5):1866-76.

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