Ubiquitin Thiolesterase

"Ubiquitin Thiolesterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A thioester hydrolase which acts on esters formed between thiols such as DITHIOTHREITOL or GLUTATHIONE and the C-terminal glycine residue of UBIQUITIN.

Descriptor ID	D043222
MeSH Number(s)	D08.811.037.500 D08.811.277.352.897.850 D12.776.637.937
Concept/Terms	Ubiquitin Thiolesterase Ubiquitin Thiolesterase Thiolesterase, Ubiquitin Ubiquitin C-Terminal Hydrolase C-Terminal Hydrolase, Ubiquitin Hydrolase, Ubiquitin C-Terminal Ubiquitin C Terminal Hydrolase Ubiquitin Carboxy-Terminal Hydrolase Carboxy-Terminal Hydrolase, Ubiquitin Hydrolase, Ubiquitin Carboxy-Terminal Ubiquitin Carboxy Terminal Hydrolase Ubiquitin C-Terminal Esterase C-Terminal Esterase, Ubiquitin Esterase, Ubiquitin C-Terminal Ubiquitin C Terminal Esterase Ubiquitin Carboxy-Terminal Esterase Carboxy-Terminal Esterase, Ubiquitin Esterase, Ubiquitin Carboxy-Terminal Ubiquitin Carboxy Terminal Esterase Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 Ubiquitin Carboxyl Terminal Hydrolase Isozyme L1 Parkinson Disease 5 Protein PARK5 Protein Neuron Cytoplasmic Protein 9.5 UCHL1 Protein Uch-L1 Protein Uch L1 Protein

Below are MeSH descriptors whose meaning is more general than "Ubiquitin Thiolesterase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Deubiquitinating Enzymes [D08.811.037]
Ubiquitin Thiolesterase [D08.811.037.500]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Thiolester Hydrolases [D08.811.277.352.897]
Ubiquitin Thiolesterase [D08.811.277.352.897.850]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Parkinson Disease Associated Proteins [D12.776.637]
Ubiquitin Thiolesterase [D12.776.637.937]

Below are MeSH descriptors whose meaning is related to "Ubiquitin Thiolesterase".

Below are MeSH descriptors whose meaning is more specific than "Ubiquitin Thiolesterase".

Ubiquitin Thiolesterase
Ubiquitin-Specific Peptidase 7

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ubiquitin Thiolesterase" by people in this website by year, and whether "Ubiquitin Thiolesterase" was a major or minor topic of these publications.

Bar chart showing 19 publications over 14 distinct years, with a maximum of 4 publications in 2026

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2008	0	1	1
2010	1	0	1
2011	1	0	1
2013	0	1	1
2014	0	1	1
2015	1	1	2
2016	1	0	1
2017	0	1	1
2018	0	1	1
2020	1	0	1
2021	1	1	2
2025	0	1	1
2026	2	2	4

Below are the most recent publications written about "Ubiquitin Thiolesterase" by people in Profiles.

Paes T, Zhang Q, Borges CO, Mohan DR, Vaz V, Soares BS, Carroll RS, Kaiser UB, Smith TR, Bi WL, Meredith D, Lerario AM, Abreu AP. Distinct genetic alterations drive Cushing disease vs silent corticotroph adenomas. J Clin Endocrinol Metab. 2026 Oct 16; 111(11):3062-3074.

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Kim JM, Yang YS, Xie J, Kang CM, Cho YC, Park KH, Gong F, Sato T, Kim BJ, Gao G, Shim JH. USP24-dependent STAT2 stabilization mediates physiologic and pathologic bone formation. Cell Death Dis. 2026 May 30; 17(1).

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Hall RR, Baccei S, Jadhav N, Most MJ. Nodular fasciitis with intra-articular presentation within the knee. BMJ Case Rep. 2026 Apr 21; 19(4).

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Chaugule S, Yang YS, Sato T, Mayer E, Shim JH. USP8-mediated mitochondrial regulation in osteoclasts is essential for skeletal development. Cell Mol Life Sci. 2026 Jan 15; 83(1):72.

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Mohan DR, Paes T, Buelvas Mebarak J, Meredith DM, Soares B, Vaz V, Carroll RS, Kaiser UB, Smith TR, Bi WL, Lerario AM, Abreu AP. Non-recurrent mutations and copy number changes predominate pituitary adenoma genomes. Eur J Endocrinol. 2025 Apr 30; 192(5):590-602.

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Chaugule S, Kim JM, Yang YS, Knobeloch KP, He X, Shim JH. Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling. Int J Mol Sci. 2021 Sep 24; 22(19).

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Lv B, Stuck MW, Desai PB, Cabrera OA, Pazour GJ. E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened. J Cell Biol. 2021 09 06; 220(9).

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Reece JT, Milone M, Wang P, Herman D, Petrov D, Shaw LM. A Biomarker for Concussion: The Good, the Bad, and the Unknown. J Appl Lab Med. 2020 01 01; 5(1):170-182.

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Di Nunno V, Frega G, Santoni M, Gatto L, Fiorentino M, Montironi R, Battelli N, Brandi G, Massari F. BAP1 in solid tumors. Future Oncol. 2019 Jun; 15(18):2151-2162.

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Fridman V, Suriyanarayanan S, Novak P, David W, Macklin EA, McKenna-Yasek D, Walsh K, Aziz-Bose R, Oaklander AL, Brown R, Hornemann T, Eichler F. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. 2019 01 22; 92(4):e359-e370.

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