Ubiquitin Thiolesterase

"Ubiquitin Thiolesterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A thioester hydrolase which acts on esters formed between thiols such as DITHIOTHREITOL or GLUTATHIONE and the C-terminal glycine residue of UBIQUITIN.

Descriptor ID	D043222
MeSH Number(s)	D08.811.037.500 D08.811.277.352.897.850 D12.776.637.937
Concept/Terms	Ubiquitin Thiolesterase Ubiquitin Thiolesterase Thiolesterase, Ubiquitin Ubiquitin C-Terminal Hydrolase C-Terminal Hydrolase, Ubiquitin Hydrolase, Ubiquitin C-Terminal Ubiquitin C Terminal Hydrolase Ubiquitin Carboxy-Terminal Hydrolase Carboxy-Terminal Hydrolase, Ubiquitin Hydrolase, Ubiquitin Carboxy-Terminal Ubiquitin Carboxy Terminal Hydrolase Ubiquitin C-Terminal Esterase C-Terminal Esterase, Ubiquitin Esterase, Ubiquitin C-Terminal Ubiquitin C Terminal Esterase Ubiquitin Carboxy-Terminal Esterase Carboxy-Terminal Esterase, Ubiquitin Esterase, Ubiquitin Carboxy-Terminal Ubiquitin Carboxy Terminal Esterase Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 Ubiquitin Carboxyl Terminal Hydrolase Isozyme L1 Parkinson Disease 5 Protein PARK5 Protein Neuron Cytoplasmic Protein 9.5 UCHL1 Protein Uch-L1 Protein Uch L1 Protein

Below are MeSH descriptors whose meaning is more general than "Ubiquitin Thiolesterase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Deubiquitinating Enzymes [D08.811.037]
Ubiquitin Thiolesterase [D08.811.037.500]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Thiolester Hydrolases [D08.811.277.352.897]
Ubiquitin Thiolesterase [D08.811.277.352.897.850]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Parkinson Disease Associated Proteins [D12.776.637]
Ubiquitin Thiolesterase [D12.776.637.937]

Below are MeSH descriptors whose meaning is related to "Ubiquitin Thiolesterase".

Below are MeSH descriptors whose meaning is more specific than "Ubiquitin Thiolesterase".

Ubiquitin Thiolesterase
Ubiquitin-Specific Peptidase 7

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ubiquitin Thiolesterase" by people in this website by year, and whether "Ubiquitin Thiolesterase" was a major or minor topic of these publications.

Bar chart showing 15 publications over 13 distinct years, with a maximum of 2 publications in 2015 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2008	0	1	1
2011	1	0	1
2013	0	1	1
2014	0	1	1
2015	1	1	2
2016	1	0	1
2017	0	1	1
2018	0	1	1
2020	1	0	1
2021	1	1	2
2025	0	1	1
2026	1	0	1

Below are the most recent publications written about "Ubiquitin Thiolesterase" by people in Profiles.

Chaugule S, Yang YS, Sato T, Mayer E, Shim JH. USP8-mediated mitochondrial regulation in osteoclasts is essential for skeletal development. Cell Mol Life Sci. 2026 Jan 15; 83(1):72.

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Mohan DR, Paes T, Buelvas Mebarak J, Meredith DM, Soares B, Vaz V, Carroll RS, Kaiser UB, Smith TR, Bi WL, Lerario AM, Abreu AP. Non-recurrent mutations and copy number changes predominate pituitary adenoma genomes. Eur J Endocrinol. 2025 Apr 30; 192(5):590-602.

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Chaugule S, Kim JM, Yang YS, Knobeloch KP, He X, Shim JH. Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling. Int J Mol Sci. 2021 Sep 24; 22(19).

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Lv B, Stuck MW, Desai PB, Cabrera OA, Pazour GJ. E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened. J Cell Biol. 2021 09 06; 220(9).

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Reece JT, Milone M, Wang P, Herman D, Petrov D, Shaw LM. A Biomarker for Concussion: The Good, the Bad, and the Unknown. J Appl Lab Med. 2020 01 01; 5(1):170-182.

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Di Nunno V, Frega G, Santoni M, Gatto L, Fiorentino M, Montironi R, Battelli N, Brandi G, Massari F. BAP1 in solid tumors. Future Oncol. 2019 Jun; 15(18):2151-2162.

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Fridman V, Suriyanarayanan S, Novak P, David W, Macklin EA, McKenna-Yasek D, Walsh K, Aziz-Bose R, Oaklander AL, Brown R, Hornemann T, Eichler F. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. 2019 01 22; 92(4):e359-e370.

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Mapa CE, Arsenault HE, Conti MM, Poti KE, Benanti JA. A balance of deubiquitinating enzymes controls cell cycle entry. Mol Biol Cell. 2018 11 15; 29(23):2821-2834.

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Adoro S, Park KH, Bettigole SE, Lis R, Shin HR, Seo H, Kim JH, Knobeloch KP, Shim JH, Glimcher LH. Post-translational control of T cell development by the ESCRT protein CHMP5. Nat Immunol. 2017 Jul; 18(7):780-790.

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Lambrus BG, Daggubati V, Uetake Y, Scott PM, Clutario KM, Sluder G, Holland AJ. A USP28-53BP1-p53-p21 signaling axis arrests growth after centrosome loss or prolonged mitosis. J Cell Biol. 2016 07 18; 214(2):143-53.

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