Ubiquitin-Specific Peptidase 7
"Ubiquitin-Specific Peptidase 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitinyl hydrolase that deubiquitinates several proteins with critical roles in DNA REPAIR, cell growth, and survival, including TUMOR SUPPRESSOR PROTEIN P53; MDM-2 PROTEIN; and PTEN PHOSPHOHYDROLASE. It also stabilizes herpesvirus 1 trans-acting transcriptional protein VMW110 during HSV-1 infection, contributing to its function as a TRANS-ACTIVATOR.
| Descriptor ID |
D000076084
|
| MeSH Number(s) |
D08.811.037.500.500 D08.811.037.750.750 D08.811.277.352.897.850.500 D08.811.277.656.300.887.875
|
| Concept/Terms |
Ubiquitin-Specific Peptidase 7- Ubiquitin-Specific Peptidase 7
- Peptidase 7, Ubiquitin-Specific
- Ubiquitin Specific Peptidase 7
- HAUSP Protein
- Herpesvirus-Associated Ubiquitin-Specific Peptidase
- Herpesvirus Associated Ubiquitin Specific Peptidase
- Peptidase, Herpesvirus-Associated Ubiquitin-Specific
- Ubiquitin-Specific Peptidase, Herpesvirus-Associated
- USP7 Protein
|
Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Specific Peptidase 7".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Specific Peptidase 7".
This graph shows the total number of publications written about "Ubiquitin-Specific Peptidase 7" by people in this website by year, and whether "Ubiquitin-Specific Peptidase 7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ubiquitin-Specific Peptidase 7" by people in Profiles.
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Kim JM, Yang YS, Park KH, Ge X, Xu R, Li N, Song M, Chun H, Bok S, Charles JF, Filhol-Cochet O, Boldyreff B, Dinter T, Yu PB, Kon N, Gu W, Takarada T, Greenblatt MB, Shim JH. A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nat Commun. 2020 05 08; 11(1):2289.
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Fang Z, Luna EJ. Supervillin-mediated suppression of p53 protein enhances cell survival. J Biol Chem. 2013 Mar 15; 288(11):7918-7929.
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Lu X, Ma O, Nguyen TA, Jones SN, Oren M, Donehower LA. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop. Cancer Cell. 2007 Oct; 12(4):342-54.
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Geoffroy MC, Epstein AL, Toublanc E, Moullier P, Salvetti A. Herpes simplex virus type 1 ICP0 protein mediates activation of adeno-associated virus type 2 rep gene expression from a latent integrated form. J Virol. 2004 Oct; 78(20):10977-86.
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Vugmeyster Y, Borodovsky A, Maurice MM, Maehr R, Furman MH, Ploegh HL. The ubiquitin-proteasome pathway in thymocyte apoptosis: caspase-dependent processing of the deubiquitinating enzyme USP7 (HAUSP). Mol Immunol. 2002 Nov; 39(7-8):431-41.