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Thomas E Akie MD, PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentEmergency Medicine
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-421-1401
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentEmergency Medicine
    DivisionResearch


    Collapse Biography 
    Collapse education and training
    Vassar College, Poughkeepsie, NY, United StatesBA
    University of Massachusetts Medical School, Worcester, MA, United StatesMD
    University of Massachusetts Medical School, Worcester, MA, United StatesPHD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mower WR, Akie TE, Morizadeh N, Gupta M, Hendey GW, Wilson JL, Leonid Duvergne LP, Ma P, Krishna P, Rodriguez RM. Blunt Head Injury in the Elderly: Analysis of the NEXUS II Injury Cohort. Ann Emerg Med. 2024 Feb 09. PMID: 38340132.
      Citations:    
    2. Akie TE, Gupta M, Rodriguez RM, Hendey GW, Wilson JL, Quinones AK, Mower WR. Physical Examination Sensitivity for Skull Fracture in Pediatric Patients With Blunt Head Trauma: A Secondary Analysis of the National Emergency X-Radiography Utilization Study II Head Computed Tomography Validation Study. Ann Emerg Med. 2023 03; 81(3):334-342. PMID: 36328857.
      Citations:    Fields:    Translation:Humans
    3. Verboon JM, Mahmut D, Kim AR, Nakamura M, Abdulhay NJ, Nandakumar SK, Gupta N, Akie TE, Geddis AE, Manes B, Kapp ME, Hofmann I, Gabriel SB, Klein DE, Williams DA, Frangoul HA, Parkhurst SM, Crane GM, Cantor AB, Sankaran VG. Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction. J Clin Immunol. 2020 05; 40(4):554-566. PMID: 32303876.
      Citations: 14     Fields:    Translation:HumansCells
    4. Nam M, Akie TE, Sanosaka M, Craige SM, Kant S, Keaney JF, Cooper MP. Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression. Sci Rep. 2017 05 17; 7(1):2013. PMID: 28515438.
      Citations: 9     Fields:    Translation:AnimalsCells
    5. Akie TE, Cooper MP. Determination of Fatty Acid Oxidation and Lipogenesis in Mouse Primary Hepatocytes. J Vis Exp. 2015 Aug 27; (102):e52982. PMID: 26382148.
      Citations: 21     Fields:    Translation:AnimalsCells
    6. Akie TE, Liu L, Nam M, Lei S, Cooper MP. OXPHOS-Mediated Induction of NAD+ Promotes Complete Oxidation of Fatty Acids and Interdicts Non-Alcoholic Fatty Liver Disease. PLoS One. 2015; 10(5):e0125617. PMID: 25933096.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    7. Liu L, Nam M, Fan W, Akie TE, Hoaglin DC, Gao G, Keaney JF, Cooper MP. Nutrient sensing by the mitochondrial transcription machinery dictates oxidative phosphorylation. J Clin Invest. 2014 Feb; 124(2):768-84. PMID: 24430182.
      Citations: 24     Fields:    Translation:AnimalsCells
    8. Woo AJ, Wieland K, Huang H, Akie TE, Piers T, Kim J, Cantor AB. Developmental differences in IFN signaling affect GATA1s-induced megakaryocyte hyperproliferation. J Clin Invest. 2013 Jul 01. PMID: 23863621.
      Citations: 21     Fields:    
    9. Roth Flach RJ, Matevossian A, Akie TE, Negrin KA, Paul MT, Czech MP. ?3-Adrenergic receptor stimulation induces E-selectin-mediated adipose tissue inflammation. J Biol Chem. 2013 Jan 25; 288(4):2882-92. PMID: 23235150.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    10. Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, Zon LI, Fraenkel E, Cantor AB. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Mol Cell. 2012 Feb 10; 45(3):330-43. PMID: 22325351.
      Citations: 109     Fields:    Translation:AnimalsCells
    11. Bai X, Kim J, Yang Z, Jurynec MJ, Akie TE, Lee J, LeBlanc J, Sessa A, Jiang H, DiBiase A, Zhou Y, Grunwald DJ, Lin S, Cantor AB, Orkin SH, Zon LI. TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell. 2010 Jul 09; 142(1):133-43. PMID: 20603019.
      Citations: 120     Fields:    Translation:HumansAnimalsCells
    12. Huang H, Yu M, Akie TE, Moran TB, Woo AJ, Tu N, Waldon Z, Lin YY, Steen H, Cantor AB. Differentiation-dependent interactions between RUNX-1 and FLI-1 during megakaryocyte development. Mol Cell Biol. 2009 Aug; 29(15):4103-15. PMID: 19470763.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    13. Sankaran VG, Menne TF, Xu J, Akie TE, Lettre G, Van Handel B, Mikkola HK, Hirschhorn JN, Cantor AB, Orkin SH. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A. Science. 2008 Dec 19; 322(5909):1839-42. PMID: 19056937.
      Citations: 441     Fields:    Translation:HumansAnimalsCells
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