John Pezzuto to NF-kappa B
This is a "connection" page, showing publications John Pezzuto has written about NF-kappa B.
Connection Strength
2.940
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Luqman S, Meena A, Marler LE, Kondratyuk TP, Pezzuto JM. Suppression of tumor necrosis factor-a-induced nuclear factor ?B activation and aromatase activity by capsaicin and its analog capsazepine. J Med Food. 2011 Nov; 14(11):1344-51.
Score: 0.315
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Morais MC, Luqman S, Kondratyuk TP, Petronio MS, Regasini LO, Silva DH, Bolzani VS, Soares CP, Pezzuto JM. Suppression of TNF-a induced NF?B activity by gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention. Nat Prod Res. 2010 Nov; 24(18):1758-65.
Score: 0.302
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Luqman S, Pezzuto JM. NFkappaB: a promising target for natural products in cancer chemoprevention. Phytother Res. 2010 Jul; 24(7):949-63.
Score: 0.295
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Asolkar RN, Freel KC, Jensen PR, Fenical W, Kondratyuk TP, Park EJ, Pezzuto JM. Arenamides A-C, cytotoxic NFkappaB inhibitors from the marine actinomycete Salinispora arenicola. J Nat Prod. 2009 Mar 27; 72(3):396-402.
Score: 0.270
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Cuendet M, Gills JJ, Pezzuto JM. Brusatol-induced HL-60 cell differentiation involves NF-kappaB activation. Cancer Lett. 2004 Mar 31; 206(1):43-50.
Score: 0.191
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Zaman KAU, Hu Z, Wu X, Hou S, Saito J, Kondratyuk TP, Pezzuto JM, Cao S. NF-?B Inhibitory and Antibacterial Helvolic and Fumagillin Derivatives from Aspergillus terreus. J Nat Prod. 2020 03 27; 83(3):730-737.
Score: 0.144
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Fatima N, Kondratyuk TP, Park EJ, Marler LE, Jadoon M, Qazi MA, Mehboob Mirza H, Khan I, Atiq N, Chang LC, Ahmed S, Pezzuto JM. Endophytic fungi associated with Taxus fuana (West Himalayan Yew) of Pakistan: potential bio-resources for cancer chemopreventive agents. Pharm Biol. 2016 Nov; 54(11):2547-2554.
Score: 0.111
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Sang-Ngern M, Youn UJ, Park EJ, Kondratyuk TP, Simmons CJ, Wall MM, Ruf M, Lorch SE, Leong E, Pezzuto JM, Chang LC. Withanolides derived from Physalis peruviana (Poha) with potential anti-inflammatory activity. Bioorg Med Chem Lett. 2016 Jun 15; 26(12):2755-2759.
Score: 0.110
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Park EJ, Shen L, Sun D, Pezzuto JM. Inhibitory effect of a callophycin A derivative on iNOS expression via inhibition of Akt in lipopolysaccharide-stimulated RAW 264.7 cells. J Nat Prod. 2014 Mar 28; 77(3):527-35.
Score: 0.093
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Andreani A, Leoni A, Locatelli A, Morigi R, Rambaldi M, Cervellati R, Greco E, Kondratyuk TP, Park EJ, Huang K, van Breemen RB, Pezzuto JM. Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles. Eur J Med Chem. 2013 Oct; 68:412-21.
Score: 0.092
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Yu X, Park EJ, Kondratyuk TP, Pezzuto JM, Sun D. Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NF?B inhibitors. Org Biomol Chem. 2012 Nov 28; 10(44):8835-47.
Score: 0.087
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Park EJ, Cheenpracha S, Chang LC, Kondratyuk TP, Pezzuto JM. Inhibition of lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression by 4-[(2'-O-acetyl-a-L-rhamnosyloxy)benzyl]isothiocyanate from Moringa oleifera. Nutr Cancer. 2011; 63(6):971-82.
Score: 0.079
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Kondratyuk TP, Park EJ, Marler LE, Ahn S, Yuan Y, Choi Y, Yu R, van Breemen RB, Sun B, Hoshino J, Cushman M, Jermihov KC, Mesecar AD, Grubbs CJ, Pezzuto JM. Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity. Mol Nutr Food Res. 2011 Aug; 55(8):1249-65.
Score: 0.079
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Nam SJ, Gaud?ncio SP, Kauffman CA, Jensen PR, Kondratyuk TP, Marler LE, Pezzuto JM, Fenical W. Fijiolides A and B, inhibitors of TNF-alpha-induced NFkappaB activation, from a marine-derived sediment bacterium of the genus Nocardiopsis. J Nat Prod. 2010 Jun 25; 73(6):1080-6.
Score: 0.074
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Endringer DC, Pezzuto JM, Braga FC. NF-kappaB inhibitory activity of cyclitols isolated from Hancornia speciosa. Phytomedicine. 2009 Nov; 16(11):1064-9.
Score: 0.068
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Kang SS, Cuendet M, Endringer DC, Croy VL, Pezzuto JM, Lipton MA. Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB. Bioorg Med Chem. 2009 Feb 01; 17(3):1044-54.
Score: 0.064
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Sang-Ngern M, Fukuchi A, Kondratyuk TP, Park EJ, Simmons CJ, Wall MM, Lorch SE, Pezzuto JM, Chang LC. Biologically active withanolides from Physalis peruviana. Pharm Biol. 2025 Dec; 63(1):334-343.
Score: 0.051
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Liu F, O'Donnell TJ, Park EJ, Kovacs S, Nakamura K, Dave A, Luo Y, Sun R, Wall M, Wongwiwatthananukit S, Silva DK, Williams PG, Pezzuto JM, Chang LC. Anti-inflammatory Quinoline Alkaloids from the Roots of Waltheria indica. J Nat Prod. 2023 02 24; 86(2):276-289.
Score: 0.044
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Cai YS, Sarotti AM, G?ndisch D, Kondratyuk TP, Pezzuto JM, Turkson J, Cao S. Heliotropiumides A and B, new phenolamides with N-carbamoyl putrescine moiety from Heliotropium foertherianum collected in Hawaii and their biological activities. Bioorg Med Chem Lett. 2017 10 15; 27(20):4630-4634.
Score: 0.030
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Youn UJ, Park EJ, Kondratyuk TP, Sripisut T, Laphookhieo S, Pezzuto JM, Chang LC. Anti-inflammatory triterpenes from the apical bud of Gardenia sootepensis. Fitoterapia. 2016 Oct; 114:92-97.
Score: 0.028
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Youn UJ, Park EJ, Kondratyuk TP, Sang-Ngern M, Wall MM, Wei Y, Pezzuto JM, Chang LC. Anti-inflammatory and Quinone Reductase Inducing Compounds from Fermented Noni (Morinda citrifolia) Juice Exudates. J Nat Prod. 2016 06 24; 79(6):1508-13.
Score: 0.028
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Youn UJ, Sripisut T, Park EJ, Kondratyuk TP, Fatima N, Simmons CJ, Wall MM, Sun D, Pezzuto JM, Chang LC. Determination of the absolute configuration of chaetoviridins and other bioactive azaphilones from the endophytic fungus Chaetomium globosum. Bioorg Med Chem Lett. 2015 Nov 01; 25(21):4719-4723.
Score: 0.026
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Jabeen F, Panda SS, Kondratyuk TP, Park EJ, Pezzuto JM, Hall CD, Katritzky AR. Synthesis, molecular docking and anticancer studies of peptides and iso-peptides. Bioorg Med Chem Lett. 2015 Aug 01; 25(15):2980-4.
Score: 0.026
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Parrish SM, Yoshida WY, Kondratyuk TP, Park EJ, Pezzuto JM, Kelly M, Williams PG. Spongiapyridine and related spongians isolated from an Indonesian Spongia sp. J Nat Prod. 2014 Jul 25; 77(7):1644-9.
Score: 0.024
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Chai X, Youn UJ, Sun D, Dai J, Williams P, Kondratyuk TP, Borris RP, Davies J, Villanueva IG, Pezzuto JM, Chang LC. Herbicidin congeners, undecose nucleosides from an organic extract of Streptomyces sp. L-9-10. J Nat Prod. 2014 Feb 28; 77(2):227-33.
Score: 0.024
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Pansanit A, Park EJ, Kondratyuk TP, Pezzuto JM, Lirdprapamongkol K, Kittakoop P. Vermelhotin, an anti-inflammatory agent, suppresses nitric oxide production in RAW 264.7 cells via p38 inhibition. J Nat Prod. 2013 Sep 27; 76(9):1824-7.
Score: 0.023
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Youn UJ, Chai X, Park EJ, Kondratyuk TP, Simmons CJ, Borris RP, Mirza B, Pezzuto JM, Chang LC. Biologically active withanolides from Withania coagulans. J Nat Prod. 2013 Jan 25; 76(1):22-8.
Score: 0.022
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Luqman S, Meena A, Singh P, Kondratyuk TP, Marler LE, Pezzuto JM, Negi AS. Neoflavonoids and tetrahydroquinolones as possible cancer chemopreventive agents. Chem Biol Drug Des. 2012 Oct; 80(4):616-24.
Score: 0.021
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Youn UJ, Park EJ, Kondratyuk TP, Simmons CJ, Borris RP, Tanamatayarat P, Wongwiwatthananukit S, Toyama O, Songsak T, Pezzuto JM, Chang LC. Anti-inflammatory sesquiterpene lactones from the flower of Vernonia cinerea. Bioorg Med Chem Lett. 2012 Sep 01; 22(17):5559-62.
Score: 0.021
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Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. Bioorg Med Chem. 2012 Jan 01; 20(1):510-20.
Score: 0.020
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Shen L, Park EJ, Kondratyuk TP, Guendisch D, Marler L, Pezzuto JM, Wright AD, Sun D. Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents. Bioorg Med Chem. 2011 Nov 01; 19(21):6182-95.
Score: 0.020
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Yang JH, Kondratyuk TP, Jermihov KC, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Huang R, Liu Y, Wang LQ, Mesecar AD, van Breemen RB, Pezzuto JM, Fong HH, Chen YG, Zhang HJ. Bioactive compounds from the fern Lepisorus contortus. J Nat Prod. 2011 Feb 25; 74(2):129-36.
Score: 0.019
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Conda-Sheridan M, Marler L, Park EJ, Kondratyuk TP, Jermihov K, Mesecar AD, Pezzuto JM, Asolkar RN, Fenical W, Cushman M. Potential chemopreventive agents based on the structure of the lead compound 2-bromo-1-hydroxyphenazine, isolated from Streptomyces species, strain CNS284. J Med Chem. 2010 Dec 23; 53(24):8688-99.
Score: 0.019
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Hoshino J, Park EJ, Kondratyuk TP, Marler L, Pezzuto JM, van Breemen RB, Mo S, Li Y, Cushman M. Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. J Med Chem. 2010 Jul 08; 53(13):5033-43.
Score: 0.018
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Endringer DC, Valadares YM, Campana PR, Campos JJ, Guimar?es KG, Pezzuto JM, Braga FC. Evaluation of Brazilian plants on cancer chemoprevention targets in vitro. Phytother Res. 2010 Jun; 24(6):928-33.
Score: 0.018
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Yang JH, Kondratyuk TP, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Pegan S, Liu Y, Wang LQ, Mesecar AD, Van Breemen RB, Pezzuto JM, Fong HH, Chen YG, Zhang HJ. Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata. Phytochemistry. 2010 Apr; 71(5-6):641-7.
Score: 0.018
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Schupp PJ, Kohlert-Schupp C, Whitefield S, Engemann A, Rohde S, Hemscheidt T, Pezzuto JM, Kondratyuk TP, Park EJ, Marler L, Rostama B, Wright AD. Cancer chemopreventive and anticancer evaluation of extracts and fractions from marine macro- and microorganisms collected from Twilight Zone waters around Guam. Nat Prod Commun. 2009 Dec; 4(12):1717-28.
Score: 0.018
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Deng Y, Balunas MJ, Kim JA, Lantvit DD, Chin YW, Chai H, Sugiarso S, Kardono LB, Fong HH, Pezzuto JM, Swanson SM, de Blanco EJ, Kinghorn AD. Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes. J Nat Prod. 2009 Jun; 72(6):1165-9.
Score: 0.017
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Maiti A, Cuendet M, Kondratyuk T, Croy VL, Pezzuto JM, Cushman M. Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis. J Med Chem. 2007 Jan 25; 50(2):350-5.
Score: 0.015
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Homhual S, Zhang HJ, Bunyapraphatsara N, Kondratyuk TP, Santarsiero BD, Mesecar AD, Herunsalee A, Chaukul W, Pezzuto JM, Fong HH. Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza. Planta Med. 2006 Feb; 72(3):255-60.
Score: 0.014