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Judith Kempfle MD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentOtolaryngology
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentOtolaryngology


    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wu MJ, Barber SR, Chari DA, Knoll RM, Kempfle J, Lee DJ, Reinshagen KL, Remenschneider AK, Kozin ED. "Transcanal view" computed tomography reformat: Applications for transcanal endoscopic ear surgery. Am J Otolaryngol. 2022 Mar-Apr; 43(2):103269. PMID: 35085919.
      Citations:    Fields:    Translation:Humans
    2. Kempfle JS, Duro MV, Zhang A, Amador CD, Kuang R, Lu R, Kashemirov BA, Edge AS, McKenna CE, Jung DH. A Novel Small Molecule Neurotrophin-3 Analogue Promotes Inner Ear Neurite Outgrowth and Synaptogenesis In vitro. Front Cell Neurosci. 2021; 15:666706. PMID: 34335184.
      Citations:    
    3. Roychowdhury P, Polanik MD, Kempfle JS, Castillo-Bustamante M, Fikucki C, Wang MJ, Kozin ED, Remenschneider AK. Does stapedotomy improve high frequency conductive hearing? Laryngoscope Investig Otolaryngol. 2021 Aug; 6(4):824-831. PMID: 34401508.
      Citations:    
    4. Kempfle JS. Endoscopic-Assisted Drug Delivery for Inner Ear Regeneration. Otolaryngol Clin North Am. 2021 Feb; 54(1):189-200. PMID: 33243375.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Benchetrit L, Kwock M, Ronner EA, Goldstein S, Shu E, Lee DJ, Mankarious LA, Caloway C, Kempfle J, Cohen MS. Assessment of Pain and Analgesic Use in Children Following Otologic Surgery. Otolaryngol Head Neck Surg. 2021 07; 165(1):206-214. PMID: 33287651.
      Citations:    Fields:    Translation:Humans
    6. Kempfle JS, Panda A, Hottin M, Vinik K, Kozin ED, Ito CJ, Remenschneider AK. Effect of Powered Air-Purifying Respirators on Speech Recognition Among Health Care Workers. Otolaryngol Head Neck Surg. 2021 01; 164(1):87-90. PMID: 32689877.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    7. Kempfle JS, Luu NC, Petrillo M, Al-Asad R, Zhang A, Edge ASB. Lin28 reprograms inner ear glia to a neuronal fate. Stem Cells. 2020 07; 38(7):890-903. PMID: 32246510.
      Citations: 5     Fields:    Translation:AnimalsCells
    8. Lubner RJ, Barber SR, Knoll RM, Kempfle J, Lee DJ, Reinshagen KL, Remenschneider AK, Kozin ED. Transcanal Computed Tomography Views for Transcanal Endoscopic Lateral Skull Base Surgery: Pilot Cadaveric Study. J Neurol Surg B Skull Base. 2021 Jun; 82(3):338-344. PMID: 34026410.
      Citations:    
    9. Bächinger D, Luu NN, Kempfle JS, Barber S, Zürrer D, Lee DJ, Curtin HD, Rauch SD, Nadol JB, Adams JC, Eckhard AH. Vestibular Aqueduct Morphology Correlates With Endolymphatic Sac Pathologies in Menière's Disease-A Correlative Histology and Computed Tomography Study. Otol Neurotol. 2019 06; 40(5):e548-e555. PMID: 31083097.
      Citations: 8     Fields:    Translation:Humans
    10. Barber SR, Wong K, Kanumuri V, Kiringoda R, Kempfle J, Remenschneider AK, Kozin ED, Lee DJ. Augmented Reality, Surgical Navigation, and 3D Printing for Transcanal Endoscopic Approach to the Petrous Apex. OTO Open. 2018 Oct-Dec; 2(4):2473974X18804492. PMID: 30719506.
      Citations:    
    11. Trakimas DR, Kempfle JS, Reinshagen KL, Lee DJ, Kozin ED, Remenschneider AK. Transcanal endoscopic infracochlear vestibular neurectomy: A pilot cadaveric study. Am J Otolaryngol. 2018 Nov - Dec; 39(6):731-736. PMID: 30104073.
      Citations: 2     Fields:    Translation:Humans
    12. Kempfle JS, Nguyen K, Hamadani C, Koen N, Edge AS, Kashemirov BA, Jung DH, McKenna CE. Bisphosphonate-Linked TrkB Agonist: Cochlea-Targeted Delivery of a Neurotrophic Agent as a Strategy for the Treatment of Hearing Loss. Bioconjug Chem. 2018 04 18; 29(4):1240-1250. PMID: 29485861.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    13. Noguchi S, Arakawa T, Fukuda S, Furuno M, Hasegawa A, Hori F, Ishikawa-Kato S, Kaida K, Kaiho A, Kanamori-Katayama M, Kawashima T, Kojima M, Kubosaki A, Manabe RI, Murata M, Nagao-Sato S, Nakazato K, Ninomiya N, Nishiyori-Sueki H, Noma S, Saijyo E, Saka A, Sakai M, Simon C, Suzuki N, Tagami M, Watanabe S, Yoshida S, Arner P, Axton RA, Babina M, Baillie JK, Barnett TC, Beckhouse AG, Blumenthal A, Bodega B, Bonetti A, Briggs J, Brombacher F, Carlisle AJ, Clevers HC, Davis CA, Detmar M, Dohi T, Edge ASB, Edinger M, Ehrlund A, Ekwall K, Endoh M, Enomoto H, Eslami A, Fagiolini M, Fairbairn L, Farach-Carson MC, Faulkner GJ, Ferrai C, Fisher ME, Forrester LM, Fujita R, Furusawa JI, Geijtenbeek TB, Gingeras T, Goldowitz D, Guhl S, Guler R, Gustincich S, Ha TJ, Hamaguchi M, Hara M, Hasegawa Y, Herlyn M, Heutink P, Hitchens KJ, Hume DA, Ikawa T, Ishizu Y, Kai C, Kawamoto H, Kawamura YI, Kempfle JS, Kenna TJ, Kere J, Khachigian LM, Kitamura T, Klein S, Klinken SP, Knox AJ, Kojima S, Koseki H, Koyasu S, Lee W, Lennartsson A, Mackay-Sim A, Mejhert N, Mizuno Y, Morikawa H, Morimoto M, Moro K, Morris KJ, Motohashi H, Mummery CL, Nakachi Y, Nakahara F, Nakamura T, Nakamura Y, Nozaki T, Ogishima S, Ohkura N, Ohno H, Ohshima M, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov DA, Passier R, Patrikakis M, Pombo A, Pradhan-Bhatt S, Qin XY, Rehli M, Rizzu P, Roy S, Sajantila A, Sakaguchi S, Sato H, Satoh H, Savvi S, Saxena A, Schmidl C, Schneider C, Schulze-Tanzil GG, Schwegmann A, Sheng G, Shin JW, Sugiyama D, Sugiyama T, Summers KM, Takahashi N, Takai J, Tanaka H, Tatsukawa H, Tomoiu A, Toyoda H, van de Wetering M, van den Berg LM, Verardo R, Vijayan D, Wells CA, Winteringham LN, Wolvetang E, Yamaguchi Y, Yamamoto M, Yanagi-Mizuochi C, Yoneda M, Yonekura Y, Zhang PG, Zucchelli S, Abugessaisa I, Arner E, Harshbarger J, Kondo A, Lassmann T, Lizio M, Sahin S, Sengstag T, Severin J, Shimoji H, Suzuki M, Suzuki H, Kawai J, Kondo N, Itoh M, Daub CO, Kasukawa T, Kawaji H, Carninci P, Forrest ARR, Hayashizaki Y. FANTOM5 CAGE profiles of human and mouse samples. Sci Data. 2017 08 29; 4:170112. PMID: 28850106.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    14. Kempfle JS, Fiorillo B, Kanumuri VV, Barber S, Edge ASB, Cunnane M, Remenschneider AK, Lee DJ, Kozin ED. Quantitative imaging analysis of transcanal endoscopic Infracochlear approach to the internal auditory canal. Am J Otolaryngol. 2017 Sep - Oct; 38(5):518-520. PMID: 28687426.
      Citations: 2     Fields:    Translation:Humans
    15. Nguyen K, Kempfle JS, Jung DH, McKenna CE. Recent advances in therapeutics and drug delivery for the treatment of inner ear diseases: a patent review (2011-2015). Expert Opin Ther Pat. 2017 Feb; 27(2):191-202. PMID: 27855527.
      Citations: 8     Fields:    Translation:HumansAnimals
    16. Kempfle JS, BuSaba NY, Dobrowski JM, Westover MB, Bianchi MT. A cost-effectiveness analysis of nasal surgery to increase continuous positive airway pressure adherence in sleep apnea patients with nasal obstruction. Laryngoscope. 2017 04; 127(4):977-983. PMID: 27653626.
      Citations: 4     Fields:    Translation:Humans
    17. Kempfle JS, Friese N, Breuer T. Torticollis: A Symptom in Severe Otitis Media. Otol Neurotol. 2016 06; 37(5):e182-4. PMID: 25391024.
      Citations:    Fields:    
    18. Kempfle JS, Turban JL, Edge AS. Sox2 in the differentiation of cochlear progenitor cells. Sci Rep. 2016 Mar 18; 6:23293. PMID: 26988140.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    19. Kempfle J, Kozin ED, Remenschneider AK, Eckhard A, Edge A, Lee DJ. Endoscopic Transcanal Retrocochlear Approach to the Internal Auditory Canal with Cochlear Preservation: Pilot Cadaveric Study. Otolaryngol Head Neck Surg. 2016 05; 154(5):920-923. PMID: 26932951.
      Citations: 5     Fields:    Translation:Humans
    20. Darrow KN, Slama MC, Kozin ED, Owoc M, Hancock K, Kempfle J, Edge A, Lacour S, Boyden E, Polley D, Brown MC, Lee DJ. Optogenetic stimulation of the cochlear nucleus using channelrhodopsin-2 evokes activity in the central auditory pathways. Brain Res. 2015 Mar 02; 1599:44-56. PMID: 25481416.
      Citations: 9     Fields:    Translation:AnimalsCells
    21. Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, Andersson R, Mungall CJ, Meehan TF, Schmeier S, Bertin N, Jørgensen M, Dimont E, Arner E, Schmidl C, Schaefer U, Medvedeva YA, Plessy C, Vitezic M, Severin J, Semple C, Ishizu Y, Young RS, Francescatto M, Alam I, Albanese D, Altschuler GM, Arakawa T, Archer JA, Arner P, Babina M, Rennie S, Balwierz PJ, Beckhouse AG, Pradhan-Bhatt S, Blake JA, Blumenthal A, Bodega B, Bonetti A, Briggs J, Brombacher F, Burroughs AM, Califano A, Cannistraci CV, Carbajo D, Chen Y, Chierici M, Ciani Y, Clevers HC, Dalla E, Davis CA, Detmar M, Diehl AD, Dohi T, Drabløs F, Edge AS, Edinger M, Ekwall K, Endoh M, Enomoto H, Fagiolini M, Fairbairn L, Fang H, Farach-Carson MC, Faulkner GJ, Favorov AV, Fisher ME, Frith MC, Fujita R, Fukuda S, Furlanello C, Furino M, Furusawa J, Geijtenbeek TB, Gibson AP, Gingeras T, Goldowitz D, Gough J, Guhl S, Guler R, Gustincich S, Ha TJ, Hamaguchi M, Hara M, Harbers M, Harshbarger J, Hasegawa A, Hasegawa Y, Hashimoto T, Herlyn M, Hitchens KJ, Ho Sui SJ, Hofmann OM, Hoof I, Hori F, Huminiecki L, Iida K, Ikawa T, Jankovic BR, Jia H, Joshi A, Jurman G, Kaczkowski B, Kai C, Kaida K, Kaiho A, Kajiyama K, Kanamori-Katayama M, Kasianov AS, Kasukawa T, Katayama S, Kato S, Kawaguchi S, Kawamoto H, Kawamura YI, Kawashima T, Kempfle JS, Kenna TJ, Kere J, Khachigian LM, Kitamura T, Klinken SP, Knox AJ, Kojima M, Kojima S, Kondo N, Koseki H, Koyasu S, Krampitz S, Kubosaki A, Kwon AT, Laros JF, Lee W, Lennartsson A, Li K, Lilje B, Lipovich L, Mackay-Sim A, Manabe R, Mar JC, Marchand B, Mathelier A, Mejhert N, Meynert A, Mizuno Y, de Lima Morais DA, Morikawa H, Morimoto M, Moro K, Motakis E, Motohashi H, Mummery CL, Murata M, Nagao-Sato S, Nakachi Y, Nakahara F, Nakamura T, Nakamura Y, Nakazato K, van Nimwegen E, Ninomiya N, Nishiyori H, Noma S, Noma S, Noazaki T, Ogishima S, Ohkura N, Ohimiya H, Ohno H, Ohshima M, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov DA, Pain A, Passier R, Patrikakis M, Persson H, Piazza S, Prendergast JG, Rackham OJ, Ramilowski JA, Rashid M, Ravasi T, Rizzu P, Roncador M, Roy S, Rye MB, Saijyo E, Sajantila A, Saka A, Sakaguchi S, Sakai M, Sato H, Savvi S, Saxena A, Schneider C, Schultes EA, Schulze-Tanzil GG, Schwegmann A, Sengstag T, Sheng G, Shimoji H, Shimoni Y, Shin JW, Simon C, Sugiyama D, Sugiyama T, Suzuki M, Suzuki N, Swoboda RK, 't Hoen PA, Tagami M, Takahashi N, Takai J, Tanaka H, Tatsukawa H, Tatum Z, Thompson M, Toyodo H, Toyoda T, Valen E, van de Wetering M, van den Berg LM, Verado R, Vijayan D, Vorontsov IE, Wasserman WW, Watanabe S, Wells CA, Winteringham LN, Wolvetang E, Wood EJ, Yamaguchi Y, Yamamoto M, Yoneda M, Yonekura Y, Yoshida S, Zabierowski SE, Zhang PG, Zhao X, Zucchelli S, Summers KM, Suzuki H, Daub CO, Kawai J, Heutink P, Hide W, Freeman TC, Lenhard B, Bajic VB, Taylor MS, Makeev VJ, Sandelin A, Hume DA, Carninci P, Hayashizaki Y. A promoter-level mammalian expression atlas. Nature. 2014 Mar 27; 507(7493):462-70. PMID: 24670764.
      Citations: 913     Fields:    Translation:HumansAnimalsCells
    22. Kao SY, Kempfle JS, Jensen JB, Perez-Fernandez D, Lysaght AC, Edge AS, Stankovic KM. Loss of osteoprotegerin expression in the inner ear causes degeneration of the cochlear nerve and sensorineural hearing loss. Neurobiol Dis. 2013 Aug; 56:25-33. PMID: 23607938.
      Citations: 14     Fields:    Translation:AnimalsCells
    23. Shi F, Kempfle JS, Edge AS. Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochlea. J Neurosci. 2012 Jul 11; 32(28):9639-48. PMID: 22787049.
      Citations: 131     Fields:    Translation:AnimalsCells
    24. Parker MA, Jiang K, Kempfle JS, Mizutari K, Simmons CL, Bieber R, Adams J, Edge AS. TAK1 expression in the cochlea: a specific marker for adult supporting cells. J Assoc Res Otolaryngol. 2011 Aug; 12(4):471-83. PMID: 21472480.
      Citations: 7     Fields:    Translation:AnimalsCells
    25. Suls A, Dedeken P, Goffin K, Van Esch H, Dupont P, Cassiman D, Kempfle J, Wuttke TV, Weber Y, Lerche H, Afawi Z, Vandenberghe W, Korczyn AD, Berkovic SF, Ekstein D, Kivity S, Ryvlin P, Claes LR, Deprez L, Maljevic S, Vargas A, Van Dyck T, Goossens D, Del-Favero J, Van Laere K, De Jonghe P, Van Paesschen W. Paroxysmal exercise-induced dyskinesia and epilepsy is due to mutations in SLC2A1, encoding the glucose transporter GLUT1. Brain. 2008 Jul; 131(Pt 7):1831-44. PMID: 18577546.
      Citations: 72     Fields:    Translation:Humans
    26. Weber YG, Storch A, Wuttke TV, Brockmann K, Kempfle J, Maljevic S, Margari L, Kamm C, Schneider SA, Huber SM, Pekrun A, Roebling R, Seebohm G, Koka S, Lang C, Kraft E, Blazevic D, Salvo-Vargas A, Fauler M, Mottaghy FM, Münchau A, Edwards MJ, Presicci A, Margari F, Gasser T, Lang F, Bhatia KP, Lehmann-Horn F, Lerche H. GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leak. J Clin Invest. 2008 Jun; 118(6):2157-68. PMID: 18451999.
      Citations: 94     Fields:    Translation:HumansAnimalsCells
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