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Accalia Mai-Wan Fu PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentProgram in Molecular Medicine
AddressUMass Chan Medical School
368 Plantation Street
Worcester MA 01605
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentProgram in Molecular Medicine

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentBiochemistry and Molecular Biotechnology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentCancer Biology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentImmunology and Microbiology Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentInterdisciplinary Graduate Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMD/PhD Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMillennium MD/PhD Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentTranslational Science

    Collapse Biography 
    Collapse education and training
    University of Ottawa, Ottawa, ON, CanadaPHD

    Collapse Overview 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fu A. Reconsidering lactate disallowance in pancreatic ? cells. Trends Endocrinol Metab. 2024 Jul 04. PMID: 38969600.
    2. Rivera Nieves AM, Wauford BM, Fu A. Mitochondrial bioenergetics, metabolism, and beyond in pancreatic ?-cells and diabetes. Front Mol Biosci. 2024; 11:1354199. PMID: 38404962.
    3. Fu A, van Rooyen L, Evans L, Armstrong N, Avizonis D, Kin T, Bird GH, Reddy A, Chouchani ET, Liesa-Roig M, Walensky LD, Shapiro AMJ, Danial NN. Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets. Cell Rep. 2021 11 23; 37(8):110037. PMID: 34818536.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    4. Mills EL, Harmon C, Jedrychowski MP, Xiao H, Garrity R, Tran NV, Bradshaw GA, Fu A, Szpyt J, Reddy A, Prendeville H, Danial NN, Gygi SP, Lynch L, Chouchani ET. UCP1 governs liver extracellular succinate and inflammatory pathogenesis. Nat Metab. 2021 05; 3(5):604-617. PMID: 34002097.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    5. Wang CH, Lundh M, Fu A, Kriszt R, Huang TL, Lynes MD, Leiria LO, Shamsi F, Darcy J, Greenwood BP, Narain NR, Tolstikov V, Smith KL, Emanuelli B, Chang YT, Hagen S, Danial NN, Kiebish MA, Tseng YH. CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice. Sci Transl Med. 2020 08 26; 12(558). PMID: 32848096.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    6. Bird GH, Fu A, Escudero S, Godes M, Opoku-Nsiah K, Wales TE, Cameron MD, Engen JR, Danial NN, Walensky LD. Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor. ACS Chem Biol. 2020 06 19; 15(6):1340-1348. PMID: 32348108.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    7. Fu A, Alvarez-Perez JC, Avizonis D, Kin T, Ficarro SB, Choi DW, Karakose E, Badur MG, Evans L, Rosselot C, Bridon G, Bird GH, Seo HS, Dhe-Paganon S, Kamphorst JJ, Stewart AF, James Shapiro AM, Marto JA, Walensky LD, Jones RG, Garcia-Ocana A, Danial NN. Glucose-dependent partitioning of arginine to the urea cycle protects ?-cells from inflammation. Nat Metab. 2020 05; 2(5):432-446. PMID: 32694660.
      Citations: 17     Fields:    Translation:HumansCells
    8. Fu A, Danial NN. Grasping for aspartate in tumour metabolism. Nat Cell Biol. 2018 07; 20(7):738-739. PMID: 29941932.
      Citations: 4     Fields:    Translation:Humans
    9. Robitaille K, Rourke JL, McBane JE, Fu A, Baird S, Du Q, Kin T, Shapiro AM, Screaton RA. High-throughput Functional Genomics Identifies Regulators of Primary Human Beta Cell Proliferation. J Biol Chem. 2016 Feb 26; 291(9):4614-25. PMID: 26740620.
      Citations: 26     Fields:    Translation:HumansCells
    10. Mailloux R, Fu A, Florian M, Petrov I, Chen Q, Coughlan MC, Laziyan M, Yan J, Caldwell D, Patry D, Lalande M, Wang GS, Willmore W, Jin X. A Northern contaminant mixture impairs pancreas function in obese and lean JCR rats and inhibits insulin secretion in MIN6 cells. Toxicology. 2015 Aug 06; 334:81-93. PMID: 26066519.
      Citations: 6     Fields:    Translation:AnimalsCells
    11. Fu A, Robitaille K, Faubert B, Reeks C, Dai XQ, Hardy AB, Sankar KS, Ogrel S, Al-Dirbashi OY, Rocheleau JV, Wheeler MB, MacDonald PE, Jones R, Screaton RA. LKB1 couples glucose metabolism to insulin secretion in mice. Diabetologia. 2015 Jul; 58(7):1513-22. PMID: 25874445.
      Citations: 15     Fields:    Translation:AnimalsCells
    12. Ljubicic S, Polak K, Fu A, Wiwczar J, Szlyk B, Chang Y, Alvarez-Perez JC, Bird GH, Walensky LD, Garcia-Oca?a A, Danial NN. Phospho-BAD BH3 mimicry protects ? cells and restores functional ? cell mass in diabetes. Cell Rep. 2015 Feb 03; 10(4):497-504. PMID: 25640178.
      Citations: 16     Fields:    Translation:AnimalsCells
    13. Sakamaki J, Fu A, Reeks C, Baird S, Depatie C, Al Azzabi M, Bardeesy N, Gingras AC, Yee SP, Screaton RA. Role of the SIK2-p35-PJA2 complex in pancreatic ?-cell functional compensation. Nat Cell Biol. 2014 Mar; 16(3):234-44. PMID: 24561619.
      Citations: 45     Fields:    Translation:AnimalsCells
    14. Eberhard CE, Fu A, Reeks C, Screaton RA. CRTC2 is required for ?-cell function and proliferation. Endocrinology. 2013 Jul; 154(7):2308-17. PMID: 23677932.
      Citations: 21     Fields:    Translation:AnimalsCells
    15. Mailloux RJ, Fu A, Robson-Doucette C, Allister EM, Wheeler MB, Screaton R, Harper ME. Glutathionylation state of uncoupling protein-2 and the control of glucose-stimulated insulin secretion. J Biol Chem. 2012 Nov 16; 287(47):39673-85. PMID: 23035124.
      Citations: 30     Fields:    Translation:AnimalsCells
    16. Fu A, Eberhard CE, Screaton RA. Role of AMPK in pancreatic beta cell function. Mol Cell Endocrinol. 2013 Feb 25; 366(2):127-34. PMID: 22766107.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    17. Milman P, Fu A, Screaton RA, Woulfe JM. Depletion of intranuclear rodlets in mouse models of diabetes. Endocr Pathol. 2010 Dec; 21(4):230-5. PMID: 20922502.
      Citations: 2     Fields:    Translation:AnimalsCells
    18. Phu do T, Wallbach M, Depatie C, Fu A, Screaton RA, Oetjen E. Regulation of the CREB coactivator TORC by the dual leucine zipper kinase at different levels. Cell Signal. 2011 Feb; 23(2):344-53. PMID: 20940047.
      Citations: 5     Fields:    Translation:AnimalsCells
    19. Fu A, Ng AC, Depatie C, Wijesekara N, He Y, Wang GS, Bardeesy N, Scott FW, Touyz RM, Wheeler MB, Screaton RA. Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice. Cell Metab. 2009 Oct; 10(4):285-95. PMID: 19808021.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    20. Fu A, Screaton RA. Using kinomics to delineate signaling pathways: control of CRTC2/TORC2 by the AMPK family. Cell Cycle. 2008 Dec 15; 7(24):3823-8. PMID: 19098422.
      Citations: 12     Fields:    Translation:HumansCells
    21. Jansson D, Ng AC, Fu A, Depatie C, Al Azzabi M, Screaton RA. Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2. Proc Natl Acad Sci U S A. 2008 Jul 22; 105(29):10161-6. PMID: 18626018.
      Citations: 64     Fields:    Translation:HumansCells
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