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Qinglan Ling PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentGenetic and Cellular Medicine
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentGenetic and Cellular Medicine

    InstitutionT.H. Chan School of Medicine
    DepartmentMicrobiology

    InstitutionT.H. Chan School of Medicine
    DepartmentNeuroNexus Institute

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentInterdisciplinary Graduate Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMillennium MD/PhD Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentTranslational Science


    Collapse Biography 
    Collapse education and training
    China Pharmaceutical University, Nanjing, , ChinaBSClinical Pharmacy
    Chinese Academy of Sciences, Beijing, , ChinaMSNeuropharmacology
    University of Houston, Houston, TX, United StatesPHDPharmacology
    Collapse awards and honors
    2022 - 2024K99 NIH Pathway to Independence Award

    Collapse Overview 
    Collapse Summary
    My lab uses genetic approaches to understand and develop treatments for mitochondrial diseases. We develop the treatments in a translatable manner to directly benefit the patient population. The diseases that we are currently working on involve genes that are encoded in both the nuclear DNA and mitochondrial DNA, with neurological manifestations.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ling Q. A "one size fits all" gene therapy for neurological disorders with mitochondrial dysfunction. Mol Ther. 2024 Jul 03; 32(7):2045-2046. PMID: 38936369.
      Citations:    
    2. Ling Q, Herstine JA, Bradbury A, Gray SJ. AAV-based in vivo gene therapy for neurological disorders. Nat Rev Drug Discov. 2023 10; 22(10):789-806. PMID: 37658167.
      Citations:    
    3. Ling Q, Rioux M, Hu Y, Lee M, Gray SJ. Adeno-associated viral vector serotype 9-based gene replacement therapy for SURF1-related Leigh syndrome. Mol Ther Methods Clin Dev. 2021 Dec 10; 23:158-168. PMID: 34703839.
      Citations:    
    4. Ling QL, Akasaka H, Chen C, Haile CN, Winoske K, Ruan KH. The Protective Effects of Up-Regulating Prostacyclin Biosynthesis on Neuron Survival in Hippocampus. J Neuroimmune Pharmacol. 2020 06; 15(2):292-308. PMID: 31897976.
      Citations:    
    5. Ling QL, Mohite AJ, Murdoch E, Akasaka H, Li QY, So SP, Ruan KH. Creating a mouse model resistant to induced ischemic stroke and cardiovascular damage. Sci Rep. 2018 01 26; 8(1):1653. PMID: 29374184.
      Citations:    
    6. Ling QL, Murdoch E, Ruan KH. How can we address the controversies surrounding the use of NSAIDS in neurodegeneration? Future Med Chem. 2016 07; 8(11):1153-5. PMID: 27357618.
      Citations:    
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