DNA, Mitochondrial

"DNA, Mitochondrial" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial GENOME is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins.

Descriptor ID	D004272
MeSH Number(s)	D13.444.308.283.225
Concept/Terms	DNA, Mitochondrial DNA, Mitochondrial mtDNA Mitochondrial DNA

Below are MeSH descriptors whose meaning is more general than "DNA, Mitochondrial".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
DNA [D13.444.308]
DNA, Circular [D13.444.308.283]
DNA, Mitochondrial [D13.444.308.283.225]

Below are MeSH descriptors whose meaning is related to "DNA, Mitochondrial".

Below are MeSH descriptors whose meaning is more specific than "DNA, Mitochondrial".

DNA, Mitochondrial
DNA, Kinetoplast

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA, Mitochondrial" by people in this website by year, and whether "DNA, Mitochondrial" was a major or minor topic of these publications.

Bar chart showing 64 publications over 26 distinct years, with a maximum of 6 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	1	2
1996	1	0	1
1998	1	0	1
2000	0	1	1
2001	1	1	2
2002	1	1	2
2004	0	1	1
2005	0	1	1
2006	1	2	3
2008	0	1	1
2009	1	1	2
2010	3	1	4
2011	1	1	2
2012	1	0	1
2013	2	1	3
2014	1	0	1
2015	2	1	3
2016	1	2	3
2017	1	1	2
2018	2	1	3
2019	1	0	1
2020	3	2	5
2021	4	1	5
2022	1	3	4
2023	1	3	4
2024	3	3	6

Below are the most recent publications written about "DNA, Mitochondrial" by people in Profiles.

Yuzefovych LV, Noh HL, Suk S, Schuler AM, Mulekar MS, Pastukh VM, Kim JK, Rachek LI. Mitochondria-Targeted DNA Repair Glycosylase hOGG1 Protects Against HFD-Induced Liver Oxidative Mitochondrial DNA Damage and Insulin Resistance in OGG1-Deficient Mice. Int J Mol Sci. 2024 Nov 13; 25(22).

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Mallick A, Haynes CM. Methods to analyze the mitochondrial unfolded protein response (UPRmt). Methods Enzymol. 2024; 707:543-564.

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Zhang WZ, Rice MC, Hoffman KL, Oromendia C, Barjaktarevic IZ, Wells JM, Hastie AT, Labaki WW, Cooper CB, Comellas AP, Criner GJ, Krishnan JA, Paine R, Hansel NN, Bowler RP, Barr RG, Peters SP, Woodruff PG, Curtis JL, Han MK, Ballman KV, Martinez FJ, Choi AM, Nakahira K, Cloonan SM, Choi ME. Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort. JCI Insight. 2024 Jun 24; 9(12).

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Jiang S, Yuan T, Rosenberger FA, Mourier A, Dragano NRV, Kremer LS, Rubalcava-Gracia D, Hansen FM, Borg M, Mennuni M, Filograna R, Alsina D, Misic J, Koolmeister C, Papadea P, de Angelis MH, Ren L, Andersson O, Unger A, Bergbrede T, Di Lucrezia R, Wibom R, Zierath JR, Krook A, Giavalisco P, Mann M, Larsson NG. Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity. Nat Metab. 2024 Jun; 6(6):1024-1035.

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Kim S, Ramalho TR, Haynes CM. Regulation of proteostasis and innate immunity via mitochondria-nuclear communication. J Cell Biol. 2024 03 04; 223(3).

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Ramalho T, Assis PA, Ojelabi O, Tan L, Carvalho B, Gardinassi L, Campos O, Lorenzi PL, Fitzgerald KA, Haynes C, Golenbock DT, Gazzinelli RT. Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells. Cell Metab. 2024 03 05; 36(3):484-497.e6.

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Dai CY, Ng CC, Hung GCC, Kirmes I, Hughes LA, Du Y, Brosnan CA, Ahier A, Hahn A, Haynes CM, Rackham O, Filipovska A, Zuryn S. ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription. Nat Cell Biol. 2023 08; 25(8):1111-1120.

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Smullen M, Olson MN, Murray LF, Suresh M, Yan G, Dawes P, Barton NJ, Mason JN, Zhang Y, Fernandez-Fontaine AA, Church GM, Mastroeni D, Wang Q, Lim ET, Chan Y, Readhead B. Modeling of mitochondrial genetic polymorphisms reveals induction of heteroplasmy by pleiotropic disease locus 10398A>G. Sci Rep. 2023 06 27; 13(1):10405.

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Pr?chnicki T, Vasconcelos MB, Robinson KS, Mangan MSJ, De Graaf D, Shkarina K, Lovotti M, Standke L, Kaiser R, Stahl R, Duthie FG, Rothe M, Antonova K, Jenster LM, Lau ZH, R?sing S, Mirza N, Gottschild C, Wachten D, G?nther C, Kufer TA, Schmidt FI, Zhong FL, Latz E. Mitochondrial damage activates the NLRP10 inflammasome. Nat Immunol. 2023 04; 24(4):595-603.

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Shahbazi R, Lipson P, Gottimukkala KSV, Lane DD, Adair JE. CRISPR Gene Editing of Hematopoietic Stem and Progenitor Cells. Methods Mol Biol. 2023; 2567:39-62.

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