Header Logo

Siva Karthik Varanasi PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentMedicine
AddressUniversity of Massachusetts Medical School
55 Lake Ave North
Worcester MA 01605
vCardDownload vCard
    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMedicine
    DivisionInnate Immunity


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chung HK, Liu C, Jambor AN, Riesenberg BP, Sun M, Casillas E, Chick B, Wang J, Ma S, Mcdonald B, He P, Yang Q, Chen T, Varanasi SK, LaPorte M, Mann TH, Chen D, Hoffmann F, Tripple V, Ho J, Cho UH, Modliszewski J, Williams A, Liu L, Wang Y, Hargreaves DC, Thaxton JE, Kaech SM, Wang W. Multi-Omics Atlas-Assisted Discovery of Transcription Factors for Selective T Cell State Programming. bioRxiv. 2024 Sep 18. PMID: 36711632.
      Citations:    
    2. Mangalhara KC, Varanasi SK, Johnson MA, Burns MJ, Rojas GR, Esparza Molt? PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS. Manipulating mitochondrial electron flow enhances tumor immunogenicity. Science. 2023 09 22; 381(6664):1316-1323. PMID: 37733872.
      Citations:    
    3. Chen D, Varanasi SK, Hara T, Traina K, Sun M, McDonald B, Farsakoglu Y, Clanton J, Xu S, Garcia-Rivera L, Mann TH, Du V, Chung HK, Xu Z, Tripple V, Casillas E, Ma S, O'Connor C, Yang Q, Zheng Y, Hunter T, Lemke G, Kaech SM. CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma. Immunity. 2023 09 12; 56(9):2086-2104.e8. PMID: 37572655.
      Citations:    
    4. Redford SE, Varanasi SK, Sanchez KK, Thorup NR, Ayres JS. CD4+ T?cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection. Cell Rep. 2023 08 29; 42(8):112814. PMID: 37490905.
      Citations:    
    5. Varanasi SK, Kaech SM, Bui JD. SnapShot: Cancer immunoediting. Cell. 2022 10 13; 185(21):4038-4038.e1. PMID: 36240741.
      Citations:    
    6. Xu S, Chaudhary O, Rodr?guez-Morales P, Sun X, Chen D, Zappasodi R, Xu Z, Pinto AFM, Williams A, Schulze I, Farsakoglu Y, Varanasi SK, Low JS, Tang W, Wang H, McDonald B, Tripple V, Downes M, Evans RM, Abumrad NA, Merghoub T, Wolchok JD, Shokhirev MN, Ho PC, Witztum JL, Emu B, Cui G, Kaech SM. Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T?cells in tumors. Immunity. 2021 07 13; 54(7):1561-1577.e7. PMID: 34102100.
      Citations:    
    7. Varanasi SK, Kumar SV, Rouse BT. Determinants of Tissue-Specific Metabolic Adaptation of T Cells. Cell Metab. 2020 12 01; 32(6):908-919. PMID: 33181092.
      Citations:    
    8. Varanasi SK, Ma S, Kaech SM. T Cell Metabolism in a State of Flux. Immunity. 2019 11 19; 51(5):783-785. PMID: 31747577.
      Citations:    
    9. Harel M, Ortenberg R, Varanasi SK, Mangalhara KC, Mardamshina M, Markovits E, Baruch EN, Tripple V, Arama-Chayoth M, Greenberg E, Shenoy A, Ayasun R, Knafo N, Xu S, Anafi L, Yanovich-Arad G, Barnabas GD, Ashkenazi S, Besser MJ, Schachter J, Bosenberg M, Shadel GS, Barshack I, Kaech SM, Markel G, Geiger T. Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence. Cell. 2019 09 19; 179(1):236-250.e18. PMID: 31495571.
      Citations:    
    10. Richey T, Foster JS, Williams AD, Williams AB, Stroh A, Macy S, Wooliver C, Heidel RE, Varanasi SK, Ergen EN, Trent DJ, Kania SA, Kennel SJ, Martin EB, Wall JS. Macrophage-Mediated Phagocytosis and Dissolution of Amyloid-Like Fibrils in Mice, Monitored by Optical Imaging. Am J Pathol. 2019 05; 189(5):989-998. PMID: 30735627.
      Citations:    
    11. Varanasi SK, Rajasagi NK, Jaggi U, Rouse BT. Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions. Mucosal Immunol. 2018 11; 11(6):1705-1715. PMID: 30087443.
      Citations:    
    12. Jaggi U, Varanasi SK, Bhela S, Rouse BT. On the role of retinoic acid in virus induced inflammatory response in cornea. Microbes Infect. 2018 Jun - Jul; 20(6):337-345. PMID: 29842984.
      Citations:    
    13. Varanasi SK, Jaggi U, Hay N, Rouse BT. Hexokinase II may be dispensable for CD4 T cell responses against a virus infection. PLoS One. 2018; 13(1):e0191533. PMID: 29352298.
      Citations:    
    14. Varanasi SK, Rouse BT. How host metabolism impacts on virus pathogenesis. Curr Opin Virol. 2018 02; 28:37-42. PMID: 29156318.
      Citations:    
    15. Varanasi SK, Donohoe D, Jaggi U, Rouse BT. Manipulating Glucose Metabolism during Different Stages of Viral Pathogenesis Can Have either Detrimental or Beneficial Effects. J Immunol. 2017 09 01; 199(5):1748-1761. PMID: 28768727.
      Citations:    
    16. Bhela S, Varanasi SK, Jaggi U, Sloan SS, Rajasagi NK, Rouse BT. The Plasticity and Stability of Regulatory T Cells during Viral-Induced Inflammatory Lesions. J Immunol. 2017 08 15; 199(4):1342-1352. PMID: 28710254.
      Citations:    
    17. Rajasagi NK, Bhela S, Varanasi SK, Rouse BT. Frontline Science: Aspirin-triggered resolvin D1 controls herpes simplex virus-induced corneal immunopathology. J Leukoc Biol. 2017 11; 102(5):1159-1171. PMID: 28584076.
      Citations:    
    18. Varanasi SK, Reddy PBJ, Bhela S, Jaggi U, Gimenez F, Rouse BT. Azacytidine Treatment Inhibits the Progression of Herpes Stromal Keratitis by Enhancing Regulatory T Cell Function. J Virol. 2017 04 01; 91(7). PMID: 28100624.
      Citations:    
    19. Gimenez F, Bhela S, Dogra P, Harvey L, Varanasi SK, Jaggi U, Rouse BT. The inflammasome NLRP3 plays a protective role against a viral immunopathological lesion. J Leukoc Biol. 2016 05; 99(5):647-57. PMID: 26516184.
      Citations:    
    20. Bhela S, Mulik S, Gimenez F, Reddy PB, Richardson RL, Varanasi SK, Jaggi U, Xu J, Lu PY, Rouse BT. Role of miR-155 in the pathogenesis of herpetic stromal keratitis. Am J Pathol. 2015 Apr; 185(4):1073-84. PMID: 25700796.
      Citations:    
    Varanasi's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (144)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _