Herpes Simplex

"Herpes Simplex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)

Descriptor ID	D006561
MeSH Number(s)	C02.256.466.382 C02.825.320 C17.800.838.790.320
Concept/Terms	Herpes Simplex Herpes Simplex Herpes Simplex Virus Infection

Below are MeSH descriptors whose meaning is more general than "Herpes Simplex".

Diseases [C]
Virus Diseases [C02]
DNA Virus Infections [C02.256]
Herpesviridae Infections [C02.256.466]
Herpes Simplex [C02.256.466.382]
Skin Diseases, Viral [C02.825]
Herpes Simplex [C02.825.320]
Skin and Connective Tissue Diseases [C17]
Skin Diseases [C17.800]
Skin Diseases, Infectious [C17.800.838]
Skin Diseases, Viral [C17.800.838.790]
Herpes Simplex [C17.800.838.790.320]

Below are MeSH descriptors whose meaning is related to "Herpes Simplex".

Below are MeSH descriptors whose meaning is more specific than "Herpes Simplex".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Herpes Simplex" by people in this website by year, and whether "Herpes Simplex" was a major or minor topic of these publications.

Bar chart showing 31 publications over 16 distinct years, with a maximum of 4 publications in 2014 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
1999	0	1	1
2002	2	0	2
2004	1	0	1
2005	1	2	3
2009	0	1	1
2011	2	0	2
2014	1	3	4
2015	1	0	1
2017	4	0	4
2018	1	0	1
2019	2	0	2
2020	1	0	1
2022	1	0	1
2023	2	1	3
2024	0	3	3

Below are the most recent publications written about "Herpes Simplex" by people in Profiles.

Dawes P, Barton NJ, Orszulak AR, Chigas SM, Tran K, Sundstrom J, Olson MN, Murray LF, Oh H, Church GM, Knipe DM, Readhead B, Chan Y, Lim ET. Basic Science and Pathogenesis. Alzheimers Dement. 2024 Dec; 20 Suppl 1:e092866.

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Sundstrom J, Vanderleeden E, Barton NJ, Redick SD, Dawes P, Murray LF, Olson MN, Tran K, Chigas SM, Orszulak AR, Church GM, Readhead B, Oh HS, Harlan DM, Knipe DM, Wang JP, Chan Y, Lim ET. Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases. Cells. 2024 Nov 29; 13(23).

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Parameswaran P, Payne L, Powers J, Rashighi M, Orzalli MH. A viral E3 ubiquitin ligase produced by herpes simplex virus 1 inhibits the NLRP1 inflammasome. J Exp Med. 2024 Aug 05; 221(8).

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Pasquero S, Gugliesi F, Biolatti M, Dell'Oste V, Albano C, Bajetto G, Griffante G, Trifir? L, Brugo B, Raviola S, Lacarbonara D, Yang Q, Sudeshna S, Barasa L, Haniff H, Thompson PR, Landolfo S, De Andrea M. Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors. PLoS Pathog. 2023 Dec; 19(12):e1011849.

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Broekema N, Mertens ME, Angelova M, Orzalli MH, Oh HS, Knipe DM. Herpes simplex virus infected cell protein 8 is required for viral inhibition of the cGAS pathway. Virology. 2023 08; 585:34-41.

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Mangione CM, Barry MJ, Nicholson WK, Cabana M, Chelmow D, Coker TR, Davis EM, Donahue KE, Ja?n CR, Kubik M, Li L, Ogedegbe G, Pbert L, Ruiz JM, Stevermer J, Wong JB. Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA. 2023 02 14; 329(6):502-507.

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Ohlrich KM, Paquette C, Servais EL. Herpes Simplex Virus-Induced Tracheoesophageal Fistula in Immunocompetent Adult. Ann Thorac Surg. 2022 08; 114(2):e153.

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Bai S, Maykel JA, Yang MX. Inflammatory pseudotumor associated with HSV infection of rectal vascular endothelium in a patient with HIV: a case report and literature review. BMC Infect Dis. 2020 Mar 19; 20(1):234.

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Orzalli MH. Human Skin Explants Recapitulate Key Features of HSV-1 Infections. J Invest Dermatol. 2019 03; 139(3):519-521.

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Lu H, Cherepanova NA, Gilmore R, Contessa JN, Lehrman MA. Targeting STT3A-oligosaccharyltransferase with NGI-1 causes herpes simplex virus 1 dysfunction. FASEB J. 2019 06; 33(6):6801-6812.

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