Herpesvirus 1, Human

"Herpesvirus 1, Human" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The type species of SIMPLEXVIRUS causing most forms of non-genital herpes simplex in humans. Primary infection occurs mainly in infants and young children and then the virus becomes latent in the dorsal root ganglion. It then is periodically reactivated throughout life causing mostly benign conditions.

Descriptor ID	D018259
MeSH Number(s)	B04.280.382.100.750.390
Concept/Terms	Herpesvirus 1, Human Herpesvirus 1, Human Herpesvirus 1 (alpha), Human Human Herpesvirus 1 HHV-1 Herpes Simplex Virus Type 1 Herpes Simplex Virus 1 HSV-1

Below are MeSH descriptors whose meaning is more general than "Herpesvirus 1, Human".

Organisms [B]
Viruses [B04]
DNA Viruses [B04.280]
Herpesviridae [B04.280.382]
Alphaherpesvirinae [B04.280.382.100]
Simplexvirus [B04.280.382.100.750]
Herpesvirus 1, Human [B04.280.382.100.750.390]

Below are MeSH descriptors whose meaning is related to "Herpesvirus 1, Human".

Below are MeSH descriptors whose meaning is more specific than "Herpesvirus 1, Human".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Herpesvirus 1, Human" by people in this website by year, and whether "Herpesvirus 1, Human" was a major or minor topic of these publications.

Bar chart showing 57 publications over 25 distinct years, with a maximum of 7 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1998	1	0	1
1999	1	0	1
2000	0	2	2
2002	1	0	1
2003	1	0	1
2004	1	0	1
2005	1	1	2
2007	2	1	3
2008	1	0	1
2009	0	1	1
2010	2	1	3
2011	1	1	2
2012	3	1	4
2013	1	0	1
2014	0	1	1
2015	1	1	2
2016	3	0	3
2017	5	2	7
2018	2	1	3
2019	3	0	3
2020	2	2	4
2021	1	1	2
2023	3	0	3
2024	3	1	4

Below are the most recent publications written about "Herpesvirus 1, Human" by people in Profiles.

Dawes P, Barton NJ, Orszulak AR, Chigas SM, Tran K, Sundstrom J, Olson MN, Murray LF, Oh H, Church GM, Knipe DM, Readhead B, Chan Y, Lim ET. Basic Science and Pathogenesis. Alzheimers Dement. 2024 Dec; 20 Suppl 1:e092866.

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Sundstrom J, Vanderleeden E, Barton NJ, Redick SD, Dawes P, Murray LF, Olson MN, Tran K, Chigas SM, Orszulak AR, Church GM, Readhead B, Oh HS, Harlan DM, Knipe DM, Wang JP, Chan Y, Lim ET. Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases. Cells. 2024 Nov 29; 13(23).

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Parameswaran P, Payne L, Powers J, Rashighi M, Orzalli MH. A viral E3 ubiquitin ligase produced by herpes simplex virus 1 inhibits the NLRP1 inflammasome. J Exp Med. 2024 Aug 05; 221(8).

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Bricio-Moreno L, Kurt-Jones EA, Sorensen EW, Luster AD, Michael BD. Using Multiphoton Intravital Microscopy to Study Neutrophil Transmigration and Blood-Brain Barrier Permeability in a Mouse Model of Herpes Simplex Virus Encephalitis. Methods Mol Biol. 2024; 2828:45-55.

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Pasquero S, Gugliesi F, Biolatti M, Dell'Oste V, Albano C, Bajetto G, Griffante G, Trifir? L, Brugo B, Raviola S, Lacarbonara D, Yang Q, Sudeshna S, Barasa L, Haniff H, Thompson PR, Landolfo S, De Andrea M. Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors. PLoS Pathog. 2023 Dec; 19(12):e1011849.

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Broekema N, Mertens ME, Angelova M, Orzalli MH, Oh HS, Knipe DM. Herpes simplex virus infected cell protein 8 is required for viral inhibition of the cGAS pathway. Virology. 2023 08; 585:34-41.

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Mangione CM, Barry MJ, Nicholson WK, Cabana M, Chelmow D, Coker TR, Davis EM, Donahue KE, Ja?n CR, Kubik M, Li L, Ogedegbe G, Pbert L, Ruiz JM, Stevermer J, Wong JB. Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA. 2023 02 14; 329(6):502-507.

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Kurt-Jones EA, Dudek TE, Watanabe D, Mandell L, Che J, Zhou S, Cao L, Greenough T, Babcock GJ, Diaz F, Oh HS, Zhou C, Finberg RW, Knipe DM. Expression of SARS coronavirus 1 spike protein from a herpesviral vector induces innate immune signaling and neutralizing antibody responses. Virology. 2021 07; 559:165-172.

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Gao R, Yu CJ, Gao L, Piatkevich KD, Neve RL, Munro JB, Upadhyayula S, Boyden ES. A highly homogeneous polymer composed of tetrahedron-like monomers for high-isotropy expansion microscopy. Nat Nanotechnol. 2021 06; 16(6):698-707.

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Haines BB, Denslow A, Grzesik P, Lee JS, Farkaly T, Hewett J, Wambua D, Kong L, Behera P, Jacques J, Goshert C, Ball M, Colthart A, Finer MH, Hayes MW, Feau S, Kennedy EM, Lerner L, Qu?va C. ONCR-177, an Oncolytic HSV-1 Designed to Potently Activate Systemic Antitumor Immunity. Cancer Immunol Res. 2021 03; 9(3):291-308.

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