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S-nitrosothiol depletion in amyotrophic lateral sclerosis.
Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS.
Pax3 functions in cell survival and in pax7 regulation.
A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes.
Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus.
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Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus.
Rother KI, Harlan DM. Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus. J Clin Invest. 2004 Oct; 114(7):877-83.
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PubMed
subject areas
Age Factors
Blood Glucose
Diabetes Mellitus, Type 1
Graft Survival
Humans
Immunosuppressive Agents
Insulin
Islets of Langerhans Transplantation
Treatment Outcome
authors with profiles
David M Harlan MD