"Endodermal Sinus Tumor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)
| Descriptor ID |
D018240
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| MeSH Number(s) |
C04.557.465.510.350
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| Concept/Terms |
Endodermal Sinus Tumor- Endodermal Sinus Tumor
- Endodermal Sinus Tumors
- Tumor, Endodermal Sinus
- Tumors, Endodermal Sinus
- Yolk Sac Tumor
- Tumor, Yolk Sac
- Tumors, Yolk Sac
- Yolk Sac Tumors
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Below are MeSH descriptors whose meaning is more general than "Endodermal Sinus Tumor".
Below are MeSH descriptors whose meaning is more specific than "Endodermal Sinus Tumor".
This graph shows the total number of publications written about "Endodermal Sinus Tumor" by people in this website by year, and whether "Endodermal Sinus Tumor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Endodermal Sinus Tumor" by people in Profiles.
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Acosta AM, Sholl LM, Cin PD, Howitt BE, Otis CN, Nucci MR. Malignant tumours of the uterus and ovaries with Mullerian and germ cell or trophoblastic components have a somatic origin and are characterised by genomic instability. Histopathology. 2020 Nov; 77(5):788-797.
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Cornejo KM, Frazier L, Lee RS, Kozakewich HP, Young RH. Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases. Am J Surg Pathol. 2015 Aug; 39(8):1121-31.
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Chander A, Otis CN, Cole LL. Pure glandular endometrioid-like yolk sac tumor of the testis. Int J Surg Pathol. 2015 Feb; 23(1):30-1.
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Pais V, Leav I, Lau KM, Jiang Z, Ho SM. Estrogen receptor-beta expression in human testicular germ cell tumors. Clin Cancer Res. 2003 Oct 01; 9(12):4475-82.