Macrophages, Alveolar

"Macrophages, Alveolar" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells.

Descriptor ID	D016676
MeSH Number(s)	A11.329.372.600 A11.627.482.600 A11.733.397.600 A15.382.680.397.600 A15.382.812.522.600
Concept/Terms	Macrophages, Alveolar Macrophages, Alveolar Pulmonary Macrophages Pulmonary Macrophage Macrophages, Pulmonary Alveolar Macrophages Alveolar Macrophage Macrophage, Alveolar Macrophage, Pulmonary

Below are MeSH descriptors whose meaning is more general than "Macrophages, Alveolar".

Anatomy [A]
Cells [A11]
Connective Tissue Cells [A11.329]
Macrophages [A11.329.372]
Macrophages, Alveolar [A11.329.372.600]
Myeloid Cells [A11.627]
Macrophages [A11.627.482]
Macrophages, Alveolar [A11.627.482.600]
Phagocytes [A11.733]
Macrophages [A11.733.397]
Macrophages, Alveolar [A11.733.397.600]
Hemic and Immune Systems [A15]
Immune System [A15.382]
Phagocytes [A15.382.680]
Macrophages [A15.382.680.397]
Macrophages, Alveolar [A15.382.680.397.600]
Mononuclear Phagocyte System [A15.382.812]
Macrophages [A15.382.812.522]
Macrophages, Alveolar [A15.382.812.522.600]

Below are MeSH descriptors whose meaning is related to "Macrophages, Alveolar".

Below are MeSH descriptors whose meaning is more specific than "Macrophages, Alveolar".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Macrophages, Alveolar" by people in this website by year, and whether "Macrophages, Alveolar" was a major or minor topic of these publications.

Bar chart showing 58 publications over 26 distinct years, with a maximum of 5 publications in 1997

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	3	2	5
2000	1	0	1
2001	0	1	1
2002	0	2	2
2003	1	0	1
2004	1	0	1
2005	2	1	3
2006	0	3	3
2007	1	2	3
2008	2	1	3
2010	0	1	1
2011	1	2	3
2012	1	3	4
2013	4	0	4
2014	0	3	3
2015	0	1	1
2016	2	0	2
2017	2	1	3
2018	1	0	1
2019	0	1	1
2020	4	0	4
2021	1	0	1
2022	1	1	2
2024	1	1	2
2026	2	0	2

Below are the most recent publications written about "Macrophages, Alveolar" by people in Profiles.

Pham LK, Cervantes MM, Lim PN, Dubey D, Tufts A, Mitchell MC, Shinkawa T, Behar SM, Rothchild AC. NRF2-mediated inhibition of alveolar macrophage MHC II expression during Mycobacterium tuberculosis infection. Cell Rep. 2026 Jun 23; 45(6):117397.

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Bub L, Evren E, Verwaerde S, Ruscitti C, Vanneste D, Ghosh P, Gao Y, Sleiers N, Deng R, L?pez Montes M, Howley K, La Rocca R, Niehrs A, Glaros V, Reina-Campos M, Dahlen B, Smed-S?rensen A, Lund H, Kreslavsky T, Bj?rkstr?m NK, Reboldi A, Bossios A, Marichal T, Lambrecht BN, Willinger T. Sensing of metabolic signals via GPR183 promotes occupation of lung macrophage niches by monocytes. J Exp Med. 2026 Apr 06; 223(4).

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Mittal E, Prasad GVRK, Upadhyay S, Sadadiwala J, Olive AJ, Yang G, Sassetti CM, Philips JA. Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice. Nat Microbiol. 2024 Nov; 9(11):2970-2984.

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Lai R, Williams T, Rakib T, Lee J, Behar SM. Heterogeneity in lung macrophage control of Mycobacterium tuberculosis is modulated by T cells. Nat Commun. 2024 Jul 08; 15(1):5710.

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Crotty K, Anton P, Coleman LG, Morris NL, Lewis SA, Samuelson DR, McMahan RH, Hartmann P, Kim A, Ratna A, Mandrekar P, Wyatt TA, Choudhry MA, Kovacs EJ, McCullough R, Yeligar SM. A critical review of recent knowledge of alcohol's effects on the immunological response in different tissues. Alcohol Clin Exp Res (Hoboken). 2023 01; 47(1):36-44.

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Arafa EI, Shenoy AT, Barker KA, Etesami NS, Martin IM, Lyon De Ana C, Na E, Odom CV, Goltry WN, Korkmaz FT, Wooten AK, Belkina AC, Guillon A, Forsberg EC, Jones MR, Quinton LJ, Mizgerd JP. Recruitment and training of alveolar macrophages after pneumococcal pneumonia. JCI Insight. 2022 03 08; 7(5).

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Pisu D, Huang L, Narang V, Theriault M, L?-Bury G, Lee B, Lakudzala AE, Mzinza DT, Mhango DV, Mitini-Nkhoma SC, Jambo KC, Singhal A, Mwandumba HC, Russell DG. Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung. J Exp Med. 2021 09 06; 218(9).

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D'Agostino MR, Lai R, Afkhami S, Khera A, Yao Y, Vaseghi-Shanjani M, Zganiacz A, Jeyanathan M, Xing Z. Airway Macrophages Mediate Mucosal Vaccine-Induced Trained Innate Immunity against Mycobacterium tuberculosis in Early Stages of Infection. J Immunol. 2020 11 15; 205(10):2750-2762.

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Wang X, Zhang D, Higham A, Wolosianka S, Gai X, Zhou L, Petersen H, Pinto-Plata V, Divo M, Silverman EK, Celli B, Singh D, Sun Y, Owen CA. ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction. Respir Res. 2020 Jul 16; 21(1):188.

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Lee J, Boyce S, Powers J, Baer C, Sassetti CM, Behar SM. CD11cHi?monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis. PLoS Pathog. 2020 06; 16(6):e1008621.

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