Extracellular Matrix

"Extracellular Matrix" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.

Descriptor ID	D005109
MeSH Number(s)	A11.284.295.310
Concept/Terms	Extracellular Matrix Extracellular Matrix Matrix, Extracellular Extracellular Matrices Matrices, Extracellular

Below are MeSH descriptors whose meaning is more general than "Extracellular Matrix".

Anatomy [A]
Cells [A11]
Cellular Structures [A11.284]
Extracellular Space [A11.284.295]
Extracellular Matrix [A11.284.295.310]

Below are MeSH descriptors whose meaning is related to "Extracellular Matrix".

Below are MeSH descriptors whose meaning is more specific than "Extracellular Matrix".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Extracellular Matrix" by people in this website by year, and whether "Extracellular Matrix" was a major or minor topic of these publications.

Bar chart showing 115 publications over 30 distinct years, with a maximum of 9 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	0	1	1
1999	0	1	1
2000	0	1	1
2001	0	1	1
2002	1	2	3
2003	1	0	1
2004	1	1	2
2005	1	3	4
2006	3	1	4
2007	3	1	4
2008	2	2	4
2009	2	2	4
2010	0	1	1
2011	1	3	4
2012	3	4	7
2013	1	1	2
2014	4	5	9
2015	5	3	8
2016	3	4	7
2017	1	5	6
2018	3	3	6
2019	2	4	6
2020	1	4	5
2021	5	1	6
2022	0	3	3
2023	1	2	3
2024	2	1	3
2025	3	4	7
2026	0	1	1

Below are the most recent publications written about "Extracellular Matrix" by people in Profiles.

Molfetta DD, Ardone M, Fracasso F, Greco MR, Tamma G, Centrone M, Barile M, Tolomeo M, Nisco A, Reshkin SJ, Cardone RA. Extracellular pH and NHE1 Regulate Ductal Branching Morphogenesis in Organotypic Cultures of Human Pancreatic Duct Epithelial Cells. J Cell Physiol. 2026 Mar; 241(3):e70156.

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Wen D, Zhang Q, van Agthoven J, Weins A, Rosales IA, Zhou W, Kim T, Vela Parada X, Colvin RB, Pollak MR, Grams ME, Schmidt IM, Waikar SS, Arnaout MA, Rhee EP. Testican-2 Interaction with the Extracellular Matrix and Podocyte Protection. J Am Soc Nephrol. 2026 Apr 01; 37(4):700-712.

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Cashman TJ, Saheera S, Blau AE, Mensah Otabil E, Nagy NY, Samenuk TD, Fitzgibbons TP, McManus DD, Trivedi CM. Epigenetic dysregulation of energy homeostasis drives aortic valve stenosis that is treatable with metformin. JCI Insight. 2025 Sep 09; 10(17).

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Bambrick M, Godfrey D, Johnson MD, Esko JD, Choudhury B, Gomez Toledo A, Paulchakrabarti M, Fortes C, Staley KJ, Duhaime AC. Release of Extracellular Matrix Components after Human Traumatic Brain Injury. eNeuro. 2025 Jun; 12(6).

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Marjan T, Lafuente-G?mez N, Rampal A, Mooney DJ, Peyton SR, Qazi TH. Cell-Instructive Biomaterials with Native-Like Biochemical Complexity. Annu Rev Biomed Eng. 2025 05; 27(1):185-209.

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Mehta MKS, Englander HE, Rao A, Jarostchuk N, Giatsidis G. Acellular Adipose Matrices Seem to Be an Effective and Safe Strategy for Soft Tissue Regeneration and Volume Restoration: A Systematic Review of Clinically Relevant Literature. Adv Wound Care (New Rochelle). 2025 10; 14(10):513-527.

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Franca CM, Lima Verde ME, Silva-Sousa AC, Mansoorifar A, Athirasala A, Subbiah R, Tahayeri A, Sousa M, Fraga MA, Visalakshan RM, Doe A, Beadle K, Finley M, Dimitriadis E, Bays J, Uroz M, Yamada KM, Chen C, Bertassoni LE. Perivascular cells function as key mediators of mechanical and structural changes in vascular capillaries. Sci Adv. 2025 Jan 10; 11(2):eadp3789.

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Rampal A, de la Fuente IF, Vu NK, Doungchawee J, Ranjan U, Peyton SR, Vachet RW. Decellularization and Enzymatic Digestion Methods to Enhance ECM Protein Detection via MALDI-MS Imaging. Anal Chem. 2025 01 14; 97(1):886-893.

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Struth E, Labaf M, Karimnia V, Liu Y, Cramer G, Dahl JB, Slack FJ, Zarringhalam K, Celli JP. Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models. Sci Rep. 2024 09 05; 14(1):20698.

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Huber RE, Babbitt C, Peyton SR. Heterogeneity of brain extracellular matrix and astrocyte activation. J Neurosci Res. 2024 May; 102(5):e25356.

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