Methadone

"Methadone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)

Descriptor ID	D008691
MeSH Number(s)	D02.522.675
Concept/Terms	Methadone Methadone Biodone Biodone Dolophine Dolophine Metadol Metadol Metasedin Metasedin Symoron Symoron Methadone Hydrochloride Methadone Hydrochloride Hydrochloride, Methadone Methadose Methadose Methex Methex Phenadone Phenadone Physeptone Physeptone Phymet Pinadone Pinadone Amidone Amidone Methaddict Methaddict

Below are MeSH descriptors whose meaning is more general than "Methadone".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Ketones [D02.522]
Methadone [D02.522.675]

Below are MeSH descriptors whose meaning is related to "Methadone".

Below are MeSH descriptors whose meaning is more specific than "Methadone".

Methadone
Methadyl Acetate

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Methadone" by people in this website by year, and whether "Methadone" was a major or minor topic of these publications.

Bar chart showing 101 publications over 27 distinct years, with a maximum of 10 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2000	1	0	1
2001	1	0	1
2002	1	1	2
2003	0	1	1
2004	1	2	3
2005	1	1	2
2006	0	2	2
2007	2	0	2
2008	3	0	3
2010	1	0	1
2011	1	1	2
2012	5	0	5
2013	1	0	1
2014	1	1	2
2015	6	0	6
2016	4	3	7
2017	4	3	7
2018	2	6	8
2019	1	3	4
2020	2	4	6
2021	0	5	5
2022	0	3	3
2023	0	6	6
2024	3	7	10
2025	3	5	8
2026	2	0	2

Below are the most recent publications written about "Methadone" by people in Profiles.

Schoenfeld EM, Soares WE, Girardin AL, Simon C, Strokes N, Lauren N, Santana CS, Beck SA, Westafer LM. "Talk About It!" Shared Decision-Making for Methadone and Buprenorphine Initiation: Development and Preliminary Evaluation of a Conversation Aid via Community-Based Participatory Research. Acad Emerg Med. 2026 03; 33(3):e70256.

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Laptook AR, Czynski A, Chahine R, Greenberg RG, Smith PB, Oliveira E, Gabrio J, Eggleston B, Das A, Lee J, Lester B, Clark D, Walsh M, Ko H, Asher CC, Friedman H, Gentle S, Rao K, Katheria A, Benninger K, Jani S, Smith MC, Khan A, Talati A, Lodhi S, Mena F, England A, Parimi P, Kylat R, Harmon H, Mannan J, Howell MP, Wright T, Snowden J. Accelerated Weaning of Opioids to Reduce Pharmacologic Exposure for Neonatal Opioid Withdrawal Syndrome: A Randomized Clinical Trial. J Pediatr. 2026 May; 292:114992.

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Wolkowicz NR, Musket CW, Sofuoglu M, Reilly ED, MacLean RR, Portnoy GA. U.S. Military Veteran Perspectives on Barriers and Facilitators to Medication Treatment for Opioid Use Disorder. Subst Use Misuse. 2026; 61(6):858-870.

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Krawczyk N, Scott J, Miller M, Coulter A, Ferguson A, Frank D, Jordan A, Joudrey P, Kimmel SD, Levander XA, Potee R, Roberts KE, Russell D, Simon R, Sue KL, Suen LW, Vincent L, Voyles N, Simon C. Envisioning a Humane and Accessible US Methadone Treatment System: Generating Policy and Practice Recommendations From the Liberate Methadone Movement. Subst Use Addctn J. 2026 04; 47(2):316-325.

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Friedmann PD, Wilson D, Stopka TJ, Bernson D, Pivovarova E, Ferguson W, Hoskinson RA, Rottapel RE, Bovell-Ammon B, Gaba A, Morgan JR, Senst T, Hayes E, Evans EA. Medications for Opioid Use Disorder in County Jails - Outcomes after Release. N Engl J Med. 2025 Sep 11; 393(10):994-1003.

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Ober AJ, Murray-Krezan C, Page K, Friedmann PD, Anderson J, Osilla KC, Ryzewicz S, Huerta S, Mazer MW, Hoskinson RA, Garvey R, Peltz A, Watkins KE, Nuckols T, IsHak WW, Mariano LT, Danovitch I. Hospital Addiction Consultation Service and Opioid Use Disorder Treatment: The START Randomized Clinical Trial. JAMA Intern Med. 2025 06 01; 185(6):624-633.

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Oliveto AH, McGaugh J, Chopra MP, Thostenson J, Mancino MJ. A randomized clinical trial of disulfiram at higher doses for the treatment of cocaine use disorder among methadone-stabilized patients. J Psychiatr Res. 2025 Jun; 186:387-395.

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Morenz AM, Nance RM, Mixson LS, Feinberg J, Smith G, Korthuis PT, Pho MT, Jenkins WD, Friedmann PD, Stopka TJ, Fanucchi LC, Miller WC, Go VF, Westergaard R, Seal DW, Zule WA, Crane HM, Delaney JA, Tsui JI. Barriers to accessing medications for opioid use disorder among rural individuals. Int J Drug Policy. 2025 06; 140:104805.

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Flanagan Balawajder E, Ducharme L, Taylor BG, Lamuda PA, Kolak M, Friedmann PD, Pollack HA, Schneider JA. Barriers to Universal Availability of Medications for Opioid Use Disorder in US Jails. JAMA Netw Open. 2025 04 01; 8(4):e255340.

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Sheen S, Choo J, Huh B, Chung M. The effect of oral methadone on the QTc interval in cancer pain patients. Pain Manag. 2025 Jan; 15(1):21-25.

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