Collagen Type I

"Collagen Type I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains.

Descriptor ID	D024042
MeSH Number(s)	D05.750.078.280.300.100 D12.776.860.300.250.300.100
Concept/Terms	Collagen Type I Collagen Type I Type I Collagen Collagen, Type I Type 1 Collagen Collagen, Type 1 Procollagen Type I Procollagen Type I Type I Procollagen Procollagen, Type I Pro alpha 1 Collagen Pro alpha 1 Collagen Pro alpha 2 Collagen Pro alpha 2 Collagen Collagen Type I, alpha1 Subunit Collagen Type I, alpha1 Subunit Collagen alpha1(I) Collagen Type I, alpha1 Chain alpha1 Type 1 Collagen Collagen Type I, alpha2 Subunit Collagen Type I, alpha2 Subunit Collagen Type I, alpha2 Chain Collagen alpha2(I) alpha-2 Type 1 Collagen alpha2 Type 1 Collagen

Below are MeSH descriptors whose meaning is more general than "Collagen Type I".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Polymers [D05.750]
Biopolymers [D05.750.078]
Collagen [D05.750.078.280]
Fibrillar Collagens [D05.750.078.280.300]
Collagen Type I [D05.750.078.280.300.100]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Scleroproteins [D12.776.860]
Extracellular Matrix Proteins [D12.776.860.300]
Collagen [D12.776.860.300.250]
Fibrillar Collagens [D12.776.860.300.250.300]
Collagen Type I [D12.776.860.300.250.300.100]

Below are MeSH descriptors whose meaning is related to "Collagen Type I".

Below are MeSH descriptors whose meaning is more specific than "Collagen Type I".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Collagen Type I" by people in this website by year, and whether "Collagen Type I" was a major or minor topic of these publications.

Bar chart showing 29 publications over 20 distinct years, with a maximum of 4 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	2	2
2003	0	1	1
2006	0	1	1
2007	0	2	2
2008	0	2	2
2009	0	1	1
2010	1	1	2
2011	1	3	4
2012	0	1	1
2013	1	0	1
2014	0	1	1
2015	0	1	1
2016	1	0	1
2017	0	1	1
2018	0	1	1
2019	1	1	2
2020	1	0	1
2022	0	1	1
2024	0	2	2
2025	0	1	1

Below are the most recent publications written about "Collagen Type I" by people in Profiles.

Li W, Sparks RP, Sun C, Yang Y, Pantano L, Kirchner R, Arghiani N, Weilheimer A, Toles BJ, Chen JY, Moran SP, Barrera V, Li Z, Zhou P, Brassil ML, Wrobel D, Ho Sui SJ, Aspnes G, Schuler M, Smith J, Medoff BD, Zhou C, Boustany-Kari CM, Rippmann JF, Santos DM, Doerner JF, Mullen AC. Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells. Nat Commun. 2025 Mar 02; 16(1):2109.

View in: PubMed
Sun C, Zhou C, Daneshvar K, Ben Saad A, Kratkiewicz AJ, Toles BJ, Arghiani N, Hess A, Chen JY, Pondick JV, York SR, Li W, Moran SP, Gentile SD, Rahman RU, Li Z, Zhou P, Sparks RP, Habboub T, Kim BM, Choi MY, Affo S, Schwabe RF, Popov YV, Mullen AC. Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in HSCs. Hepatology. 2025 Mar 01; 81(3):853-869.

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Min K, Yenilmez B, Kelly M, Echeverria D, Elleby M, Lifshitz LM, Raymond N, Tsagkaraki E, Harney SM, DiMarzio C, Wang H, McHugh N, Bramato B, Morrison B, Rothstein JD, Khvorova A, Czech MP. Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis. Elife. 2024 Apr 02; 12.

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Mao M, Zhu S, Zhang L, Liu F, Kong L, Xue Y, Rotello VM, Han Y. An Extracellular Matrix-like Surface for Zn Alloy to Enhance Bone Regeneration. ACS Appl Mater Interfaces. 2022 Sep 28; 14(38):43955-43964.

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Zhang L, Gopalakrishnan S, Li K, Wang LS, Han Y, Rotello VM. Fabrication of Collagen Films with Enhanced Mechanical and Enzymatic Stability through Thermal Treatment in Fluorous Media. ACS Appl Mater Interfaces. 2020 Feb 05; 12(5):6590-6597.

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Toor RH, Malik S, Qamar H, Batool F, Tariq M, Nasir Z, Tassaduq R, Lian JB, Stein JL, Stein GS, Shakoori AR. Osteogenic potential of hexane and dichloromethane fraction of Cissus quadrangularis on murine preosteoblast cell line MC3T3-E1 (subclone 4). J Cell Physiol. 2019 12; 234(12):23082-23096.

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Miao X, Fan B, Li R, Zhang S, Lin H. Network Analysis of Depression-Related Transcriptomic Profiles. Neuromolecular Med. 2019 06; 21(2):143-149.

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Maron MS, Chan RH, Kapur NK, Jaffe IZ, McGraw AP, Kerur R, Maron BJ, Udelson JE. Effect of Spironolactone on Myocardial Fibrosis and Other Clinical Variables in Patients with Hypertrophic Cardiomyopathy. Am J Med. 2018 07; 131(7):837-841.

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Filion TM, Skelly JD, Huang H, Greiner DL, Ayers DC, Song J. Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue. Stem Cell Res Ther. 2017 03 11; 8(1):65.

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Padilla-Martinez JP, Wang R, Franco W. Evaluation of cell and matrix mechanics using fluorescence excitation spectroscopy: Feasibility study in collagen gels containing fibroblasts. Lasers Surg Med. 2016 Apr; 48(4):377-84.

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