"Compassionate Use Trials" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Providing an investigational therapy to a patient who is not eligible to receive that therapy in a clinical trial, but who has a serious or life-threatening illness for which other treatments are not available. Compassionate use trials allow patients to receive promising but not yet fully studied or approved therapies when no other treatment option exists. Also called expanded access trial.
Descriptor ID |
D057176
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MeSH Number(s) |
E02.931.500 E05.337.300.199
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Concept/Terms |
Compassionate Use Trials- Compassionate Use Trials
- Compassionate Use Trial
- Trial, Compassionate Use
- Trials, Compassionate Use
- Use Trials, Compassionate
- Expanded Access Trials
- Access Trial, Expanded
- Expanded Access Trial
- Trial, Expanded Access
- Trials, Expanded Access
Humanitarian Device Exemption- Humanitarian Device Exemption
- Device Exemption, Humanitarian
- Device Exemptions, Humanitarian
- Exemption, Humanitarian Device
- Exemptions, Humanitarian Device
- Humanitarian Device Exemptions
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Below are MeSH descriptors whose meaning is more general than "Compassionate Use Trials".
Below are MeSH descriptors whose meaning is more specific than "Compassionate Use Trials".
This graph shows the total number of publications written about "Compassionate Use Trials" by people in this website by year, and whether "Compassionate Use Trials" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2019 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Compassionate Use Trials" by people in Profiles.
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Basso U, Procopio G, Fornarini G, Massari F, Bearz A, Fratino L, Milella M, Bassanelli M, Ermacora P, Bimbatti D, Verzoni E, Rizzo M, Porta C. Safety and Efficacy of Tivozanib in First-Line mRCC: A Multicenter Compassionate-Use Study (Meet-Uro 16). Oncology. 2021; 99(12):747-755.
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Lopez-Gomez C, Sanchez-Quintero MJ, Lee EJ, Kleiner G, Tadesse S, Xie J, Akman HO, Gao G, Hirano M. Synergistic Deoxynucleoside and Gene Therapies for Thymidine Kinase 2 Deficiency. Ann Neurol. 2021 10; 90(4):640-652.
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Jankowitz BT, Hanel R, Jadhav AP, Loy DN, Frei D, Siddiqui AH, Puri AS, Khaldi A, Turk AS, Malek AM, Sauvageau E, Hetts SW, Zaidat OO. Neuroform Atlas Stent System for the treatment of intracranial aneurysm: primary results of the Atlas Humanitarian Device Exemption cohort. J Neurointerv Surg. 2019 Aug; 11(8):801-806.
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Caffo O, De Giorgi U, Fratino L, Lo Re G, Basso U, D'Angelo A, Donini M, Verderame F, Ratta R, Procopio G, Campadelli E, Massari F, Gasparro D, Macrini S, Messina C, Giordano M, Alesini D, Zustovich F, Fraccon AP, Vicario G, Conteduca V, Maines F, Galligioni E. Safety and clinical outcomes of patients treated with abiraterone acetate after docetaxel: results of the Italian Named Patient Programme. BJU Int. 2015 May; 115(5):764-71.
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Weinstein S, Bello R, Pizarro C, Fynn-Thompson F, Kirklin J, Guleserian K, Woods R, Tjossem C, Kroslowitz R, Friedmann P, Jaquiss R. The use of the Berlin Heart EXCOR in patients with functional single ventricle. J Thorac Cardiovasc Surg. 2014 Feb; 147(2):697-704; discussion 704-5.
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Fitzgerald MC, Chan JY, Ross AW, Liew SM, Butt WW, Baguley D, Salem HH, Russ MK, Deasy C, Martin KE, Mathew JK, Rosenfeld JV. A synthetic haemoglobin-based oxygen carrier and the reversal of cardiac hypoxia secondary to severe anaemia following trauma. Med J Aust. 2011 May 02; 194(9):471-3.