"Lactoylglutathione Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the interconversion of methylglyoxal and lactate, with glutathione serving as a coenzyme. EC 4.4.1.5.
Descriptor ID |
D007791
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MeSH Number(s) |
D08.811.520.300.500
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Concept/Terms |
Lactoylglutathione Lyase- Lactoylglutathione Lyase
- Lyase, Lactoylglutathione
- Methylglyoxalase
- Glyoxalase I
- Lactoyl Glutathione Lyase
- Glutathione Lyase, Lactoyl
- Lyase, Lactoyl Glutathione
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Below are MeSH descriptors whose meaning is more general than "Lactoylglutathione Lyase".
Below are MeSH descriptors whose meaning is more specific than "Lactoylglutathione Lyase".
This graph shows the total number of publications written about "Lactoylglutathione Lyase" by people in this website by year, and whether "Lactoylglutathione Lyase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 1 | 0 | 1 |
2001 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lactoylglutathione Lyase" by people in Profiles.
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Maroney MJ, Ciurli S. Nonredox nickel enzymes. Chem Rev. 2014 Apr 23; 114(8):4206-28.
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Chen F, Wollmer MA, Hoerndli F, M?nch G, Kuhla B, Rogaev EI, Tsolaki M, Papassotiropoulos A, G?tz J. Role for glyoxalase I in Alzheimer's disease. Proc Natl Acad Sci U S A. 2004 May 18; 101(20):7687-92.
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Davidson G, Clugston SL, Honek JF, Maroney MJ. An XAS investigation of product and inhibitor complexes of Ni-containing GlxI from Escherichia coli: mechanistic implications. Biochemistry. 2001 Apr 17; 40(15):4569-82.
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Davidson G, Clugston SL, Honek JF, Maroney MJ. XAS investigation of the nickel active site structure in Escherichia coli glyoxalase I. Inorg Chem. 2000 Jul 10; 39(14):2962-3.