Luteinizing Hormone, beta Subunit
"Luteinizing Hormone, beta Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.
Descriptor ID |
D037101
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MeSH Number(s) |
D06.472.699.322.576.463.500 D06.472.699.631.525.343.463.500 D12.644.548.691.525.343.463.500
|
Concept/Terms |
Luteinizing Hormone, beta Subunit- Luteinizing Hormone, beta Subunit
- Lutropin, beta Subunit
- Luteinizing Hormone, beta Chain
- Luteinizing Hormone, beta Polypeptide Chain
- Lutropin-beta
- Lutropin beta
- ICSH, beta Subunit
- LH-beta
- LH beta
- LH, beta Subunit
|
Below are MeSH descriptors whose meaning is more general than "Luteinizing Hormone, beta Subunit".
- Chemicals and Drugs [D]
- Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
- Peptide Hormones [D06.472.699]
- Gonadotropins [D06.472.699.322]
- Gonadotropins, Pituitary [D06.472.699.322.576]
- Luteinizing Hormone [D06.472.699.322.576.463]
- Luteinizing Hormone, beta Subunit [D06.472.699.322.576.463.500]
- Pituitary Hormones [D06.472.699.631]
- Pituitary Hormones, Anterior [D06.472.699.631.525]
- Gonadotropins, Pituitary [D06.472.699.631.525.343]
- Luteinizing Hormone [D06.472.699.631.525.343.463]
- Luteinizing Hormone, beta Subunit [D06.472.699.631.525.343.463.500]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Peptide Hormones [D12.644.548]
- Pituitary Hormones [D12.644.548.691]
- Pituitary Hormones, Anterior [D12.644.548.691.525]
- Gonadotropins, Pituitary [D12.644.548.691.525.343]
- Luteinizing Hormone [D12.644.548.691.525.343.463]
- Luteinizing Hormone, beta Subunit [D12.644.548.691.525.343.463.500]
Below are MeSH descriptors whose meaning is more specific than "Luteinizing Hormone, beta Subunit".
This graph shows the total number of publications written about "Luteinizing Hormone, beta Subunit" by people in this website by year, and whether "Luteinizing Hormone, beta Subunit" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 0 | 1 |
2016 | 0 | 2 | 2 |
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Below are the most recent publications written about "Luteinizing Hormone, beta Subunit" by people in Profiles.
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Khan SA, Edwards BS, Muth A, Thompson PR, Cherrington BD, Navratil AM. GnRH Stimulates Peptidylarginine Deiminase Catalyzed Histone Citrullination in Gonadotrope Cells. Mol Endocrinol. 2016 Oct; 30(10):1081-1091.
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Thompson IR, Ciccone NA, Zhou Q, Xu S, Khogeer A, Carroll RS, Kaiser UB. GnRH Pulse Frequency Control of Fshb Gene Expression Is Mediated via ERK1/2 Regulation of ICER. Mol Endocrinol. 2016 Mar; 30(3):348-60.
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Cao J, Patisaul HB, Petersen SL. Aryl hydrocarbon receptor activation in lactotropes and gonadotropes interferes with estradiol-dependent and -independent preprolactin, glycoprotein alpha and luteinizing hormone beta gene expression. Mol Cell Endocrinol. 2011 Feb 20; 333(2):151-9.