Hydrochlorothiazide

"Hydrochlorothiazide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.

Descriptor ID	D006852
MeSH Number(s)	D02.886.590.700.135.261.476 D02.886.655.500.261.476 D03.633.100.174.261.476
Concept/Terms	Hydrochlorothiazide Hydrochlorothiazide HCTZ Dichlothiazide Dihydrochlorothiazide HydroDIURIL HydroDIURIL Oretic Oretic Sectrazide Sectrazide Esidrix Esidrix Esidrex Hypothiazide Hypothiazide

Below are MeSH descriptors whose meaning is more general than "Hydrochlorothiazide".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Sulfur Compounds [D02.886]
Sulfones [D02.886.590]
Sulfonamides [D02.886.590.700]
Benzothiadiazines [D02.886.590.700.135]
Chlorothiazide [D02.886.590.700.135.261]
Hydrochlorothiazide [D02.886.590.700.135.261.476]
Thiazides [D02.886.655]
Benzothiadiazines [D02.886.655.500]
Chlorothiazide [D02.886.655.500.261]
Hydrochlorothiazide [D02.886.655.500.261.476]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Benzothiadiazines [D03.633.100.174]
Chlorothiazide [D03.633.100.174.261]
Hydrochlorothiazide [D03.633.100.174.261.476]

Below are MeSH descriptors whose meaning is related to "Hydrochlorothiazide".

Below are MeSH descriptors whose meaning is more specific than "Hydrochlorothiazide".

Hydrochlorothiazide
Trichlormethiazide

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hydrochlorothiazide" by people in this website by year, and whether "Hydrochlorothiazide" was a major or minor topic of these publications.

Bar chart showing 3 publications over 3 distinct years, with a maximum of 1 publications in 2003 and 2018 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	0	1
2018	1	0	1
2019	0	1	1

Below are the most recent publications written about "Hydrochlorothiazide" by people in Profiles.

Iniesta R, Campbell D, Venturini C, Faconti L, Singh S, Irvin MR, Cooper-DeHoff RM, Johnson JA, Turner ST, Arnett DK, Weale ME, Warren H, Munroe PB, Cruickshank K, Padmanabhan S, Lewis C, Chowienczyk P. Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals. Hypertension. 2019 09; 74(3):614-622.

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Jansson PS, Leisten DC, Sarkisian TM, Wilcox SR, Lee J. Recurrent Hydrochlorothiazide-Induced Acute Respiratory Distress Syndrome Treated With Extracorporeal Membrane Oxygenation. J Emerg Med. 2018 Dec; 55(6):836-840.

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Carey KM, Comee MR, Donovan JL, Kanaan AO. A polypill for all? Critical review of the polypill literature for primary prevention of cardiovascular disease and stroke. Ann Pharmacother. 2012 May; 46(5):688-95.

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Wright JT, Bakris GL, Bell DS, Fonseca V, Katholi RE, McGill JB, Messerli FH, Phillips RA, Raskin P, Holdbrook FK, Lukas MA, Iyengar M. Lowering blood pressure with beta-blockers in combination with other renin-angiotensin system blockers in patients with hypertension and type 2 diabetes: results from the GEMINI Trial. J Clin Hypertens (Greenwich). 2007 Nov; 9(11):842-9.

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Pitt B, Reichek N, Willenbrock R, Zannad F, Phillips RA, Roniker B, Kleiman J, Krause S, Burns D, Williams GH. Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy study. Circulation. 2003 Oct 14; 108(15):1831-8.

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Carretta R, Trenkwalder P, Martinez F, Tykarski A, Teitelbaum I, Fagan T, Oddou P, Mallion J. Pulse pressure responses in patients treated with Valsartan and hydrochlorothiazide combination therapy. J Int Med Res. 2003 Sep-Oct; 31(5):370-7.

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Phillips RA, Kloner RA, Grimm RH, Weinberger M. The effects of amlodipine compared to losartan in patients with mild to moderately severe hypertension. J Clin Hypertens (Greenwich). 2003 Jan-Feb; 5(1):17-23.

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Rochon PA, Anderson GM, Tu JV, Gurwitz JH, Clark JP, Shear NH, Lau P. Age- and gender-related use of low-dose drug therapy: the need to manufacture low-dose therapy and evaluate the minimum effective dose. J Am Geriatr Soc. 1999 Aug; 47(8):954-9.

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Gurwitz JH, Everitt DE, Monane M, Glynn RJ, Choodnovskiy I, Beaudet MP, Avorn J. The impact of ibuprofen on the efficacy of antihypertensive treatment with hydrochlorothiazide in elderly persons. J Gerontol A Biol Sci Med Sci. 1996 Mar; 51(2):M74-9.

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Lacourci?re Y, Brunner H, Irwin R, Karlberg BE, Ramsay LE, Snavely DB, Dobbins TW, Faison EP, Nelson EB. Effects of modulators of the renin-angiotensin-aldosterone system on cough. Losartan Cough Study Group. J Hypertens. 1994 Dec; 12(12):1387-93.

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