Electron Transport Complex IV

"Electron Transport Complex IV" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13 different protein subunits. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects electrons that are transferred from the reduced CYTOCHROME C GROUP and donates them to molecular OXYGEN, which is then reduced to water. The redox reaction is simultaneously coupled to the transport of PROTONS across the inner mitochondrial membrane.

Descriptor ID	D003576
MeSH Number(s)	D05.500.562.374 D08.811.600.250.687 D08.811.682.285 D12.776.157.530.450.250.875.304 D12.776.543.277.687 D12.776.543.585.450.250.875.484
Concept/Terms	Electron Transport Complex IV Electron Transport Complex IV Ferrocytochrome c Oxygen Oxidoreductase Cytochrome-c Oxidase (Complex IV) Cytochrome Oxidase Oxidase, Cytochrome Cytochrome-c Oxidase Cytochrome c Oxidase Oxidase, Cytochrome-c Signal Peptide p25-Subunit IV Cytochrome Oxidase Signal Peptide p25-Subunit IV Cytochrome Oxidase Signal Peptide p25 Subunit IV Cytochrome Oxidase Pre-CTOX p25 p25 Presequence Peptide-Cytochrome Oxidase p25 Presequence Peptide Cytochrome Oxidase Cytochrome-c Oxidase Subunit III Cytochrome-c Oxidase Subunit III Cytochrome c Oxidase Subunit III Subunit III, Cytochrome Oxidase Cytochrome Oxidase Subunit III Cytochrome-c Oxidase Subunit IV Cytochrome-c Oxidase Subunit IV Cytochrome c Oxidase Subunit IV Cytochrome aa3 Cytochrome aa3 Heme aa3 Cytochrome Oxidase Cytochrome a,a3 Cytochrome c Oxidase Subunit VIa Cytochrome c Oxidase Subunit VIa

Below are MeSH descriptors whose meaning is more general than "Electron Transport Complex IV".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Multiprotein Complexes [D05.500]
Multienzyme Complexes [D05.500.562]
Electron Transport Complex IV [D05.500.562.374]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Multienzyme Complexes [D08.811.600]
Electron Transport Chain Complex Proteins [D08.811.600.250]
Electron Transport Complex IV [D08.811.600.250.687]
Oxidoreductases [D08.811.682]
Electron Transport Complex IV [D08.811.682.285]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Pumps [D12.776.157.530.450]
Cation Transport Proteins [D12.776.157.530.450.250]
Proton Pumps [D12.776.157.530.450.250.875]
Electron Transport Complex IV [D12.776.157.530.450.250.875.304]
Membrane Proteins [D12.776.543]
Electron Transport Chain Complex Proteins [D12.776.543.277]
Electron Transport Complex IV [D12.776.543.277.687]
Membrane Transport Proteins [D12.776.543.585]
Ion Pumps [D12.776.543.585.450]
Cation Transport Proteins [D12.776.543.585.450.250]
Proton Pumps [D12.776.543.585.450.250.875]
Electron Transport Complex IV [D12.776.543.585.450.250.875.484]

Below are MeSH descriptors whose meaning is related to "Electron Transport Complex IV".

Below are MeSH descriptors whose meaning is more specific than "Electron Transport Complex IV".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Electron Transport Complex IV" by people in this website by year, and whether "Electron Transport Complex IV" was a major or minor topic of these publications.

Bar chart showing 12 publications over 8 distinct years, with a maximum of 3 publications in 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2000	0	1	1
2002	0	2	2
2004	0	1	1
2010	0	1	1
2013	1	1	2
2021	1	2	3
2025	0	1	1

Below are the most recent publications written about "Electron Transport Complex IV" by people in Profiles.

Wann C, Tep B, Suriyasathaporn W, Morita Y, Pheng V, Ohkura S, Matsuyama S, Nakamura S, Hayashi K. MORPHOLOGICAL OBSERVATION AND DETAILED MOLECULAR CHARACTERIZATION OF FISCHOEDERIUS ELONGATUS (DIGENEA: GASTROTHYLACIDAE) FROM THE RUMEN OF DOMESTIC CATTLE IN CAMBODIA. J Parasitol. 2025 Mar 01; 111(2):143-152.

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Spinelli JB, Rosen PC, Sprenger HG, Puszynska AM, Mann JL, Roessler JM, Cangelosi AL, Henne A, Condon KJ, Zhang T, Kunchok T, Lewis CA, Chandel NS, Sabatini DM. Fumarate is a terminal electron acceptor in the mammalian electron transport chain. Science. 2021 Dec 03; 374(6572):1227-1237.

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Shih YH, Portman D, Idrizi F, Grosse A, Lawson ND. Integrated molecular analysis identifies a conserved pericyte gene signature in zebrafish. Development. 2021 12 01; 148(23).

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Cai Y, Jaecklein E, Mackenzie JS, Papavinasasundaram K, Olive AJ, Chen X, Steyn AJC, Sassetti CM. Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase. PLoS Pathog. 2021 07; 17(7):e1008911.

View in: PubMed
Wen F, Caputo G, Hooey S, Bowman S, Pinkney K, Krell PJ, Arif B, Doucet D. Establishment of a cell line from the ash and privet borer beetle Tylonotus bimaculatus Haldeman and assessment of its sensitivity to diacylhydrazine insecticides. In Vitro Cell Dev Biol Anim. 2015 Oct; 51(9):905-14.

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Sharma PP, Zardus JD, Boyle EE, Gonz?lez VL, Jennings RM, McIntyre E, Wheeler WC, Etter RJ, Giribet G. Into the deep: a phylogenetic approach to the bivalve subclass Protobranchia. Mol Phylogenet Evol. 2013 Oct; 69(1):188-204.

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Raimunda D, Padilla-Benavides T, Vogt S, Boutigny S, Tomkinson KN, Finney LA, Arg?ello JM. Periplasmic response upon disruption of transmembrane Cu transport in Pseudomonas aeruginosa. Metallomics. 2013 Feb; 5(2):144-51.

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Ogborn DI, Smith KJ, Crane JD, Safdar A, Hettinga BP, Tupler R, Tarnopolsky MA. Effects of creatine and exercise on skeletal muscle of FRG1-transgenic mice. Can J Neurol Sci. 2012 Mar; 39(2):225-31.

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Poirier GL, Amin E, Good MA, Aggleton JP. Early-onset dysfunction of retrosplenial cortex precedes overt amyloid plaque formation in Tg2576 mice. Neuroscience. 2011 Feb 03; 174:71-83.

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Ferreira IL, Nascimento MV, Ribeiro M, Almeida S, Cardoso SM, Grazina M, Pratas J, Santos MJ, Janu?rio C, Oliveira CR, Rego AC. Mitochondrial-dependent apoptosis in Huntington's disease human cybrids. Exp Neurol. 2010 Apr; 222(2):243-55.

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