Paul Thompson to Substrate Specificity
This is a "connection" page, showing publications Paul Thompson has written about Substrate Specificity.
Connection Strength
1.270
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Tilvawala R, Thompson PR. Peptidyl arginine deiminases: detection and functional analysis of protein citrullination. Curr Opin Struct Biol. 2019 12; 59:205-215.
Score: 0.144
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Dreyton CJ, Knuckley B, Jones JE, Lewallen DM, Thompson PR. Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism. Biochemistry. 2014 Jul 15; 53(27):4426-33.
Score: 0.104
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Rust HL, Subramanian V, West GM, Young DD, Schultz PG, Thompson PR. Using unnatural amino acid mutagenesis to probe the regulation of PRMT1. ACS Chem Biol. 2014 Mar 21; 9(3):649-55.
Score: 0.101
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Wang M, Xu RM, Thompson PR. Substrate specificity, processivity, and kinetic mechanism of protein arginine methyltransferase 5. Biochemistry. 2013 Aug 13; 52(32):5430-40.
Score: 0.098
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Jones JE, Slack JL, Fang P, Zhang X, Subramanian V, Causey CP, Coonrod SA, Guo M, Thompson PR. Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. ACS Chem Biol. 2012 Jan 20; 7(1):160-5.
Score: 0.086
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Rust HL, Zurita-Lopez CI, Clarke S, Thompson PR. Mechanistic studies on transcriptional coactivator protein arginine methyltransferase 1. Biochemistry. 2011 Apr 26; 50(16):3332-45.
Score: 0.083
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Bicker KL, Obianyo O, Rust HL, Thompson PR. A combinatorial approach to characterize the substrate specificity of protein arginine methyltransferase 1. Mol Biosyst. 2011 Jan; 7(1):48-51.
Score: 0.079
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Knuckley B, Causey CP, Jones JE, Bhatia M, Dreyton CJ, Osborne TC, Takahara H, Thompson PR. Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3. Biochemistry. 2010 Jun 15; 49(23):4852-63.
Score: 0.079
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Jones JE, Causey CP, Lovelace L, Knuckley B, Flick H, Lebioda L, Thompson PR. Characterization and inactivation of an agmatine deiminase from Helicobacter pylori. Bioorg Chem. 2010 Apr; 38(2):62-73.
Score: 0.076
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Osborne T, Roska RL, Rajski SR, Thompson PR. In situ generation of a bisubstrate analogue for protein arginine methyltransferase 1. J Am Chem Soc. 2008 Apr 09; 130(14):4574-5.
Score: 0.067
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Osborne TC, Obianyo O, Zhang X, Cheng X, Thompson PR. Protein arginine methyltransferase 1: positively charged residues in substrate peptides distal to the site of methylation are important for substrate binding and catalysis. Biochemistry. 2007 Nov 20; 46(46):13370-81.
Score: 0.065
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Knuckley B, Bhatia M, Thompson PR. Protein arginine deiminase 4: evidence for a reverse protonation mechanism. Biochemistry. 2007 Jun 05; 46(22):6578-87.
Score: 0.063
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Kearney PL, Bhatia M, Jones NG, Yuan L, Glascock MC, Catchings KL, Yamada M, Thompson PR. Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis. Biochemistry. 2005 Aug 09; 44(31):10570-82.
Score: 0.056
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Thompson PR, Boehr DD, Berghuis AM, Wright GD. Mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: role of the nucleotide positioning loop. Biochemistry. 2002 Jun 04; 41(22):7001-7.
Score: 0.045
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Funabashi K, Sawata M, Nagai A, Akimoto M, Mashimo R, Takahara H, Kizawa K, Thompson PR, Ite K, Kitanishi K, Unno M. Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design. Arch Biochem Biophys. 2021 Sep 15; 708:108911.
Score: 0.042
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Foyn H, Thompson PR, Arnesen T. DTNB-Based Quantification of In Vitro Enzymatic N-Terminal Acetyltransferase Activity. Methods Mol Biol. 2017; 1574:9-15.
Score: 0.031
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Lewis HD, Liddle J, Coote JE, Atkinson SJ, Barker MD, Bax BD, Bicker KL, Bingham RP, Campbell M, Chen YH, Chung CW, Craggs PD, Davis RP, Eberhard D, Joberty G, Lind KE, Locke K, Maller C, Martinod K, Patten C, Polyakova O, Rise CE, R?diger M, Sheppard RJ, Slade DJ, Thomas P, Thorpe J, Yao G, Drewes G, Wagner DD, Thompson PR, Prinjha RK, Wilson DM. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol. 2015 Mar; 11(3):189-91.
Score: 0.027
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Foyn H, Jones JE, Lewallen D, Narawane R, Varhaug JE, Thompson PR, Arnesen T. Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors. ACS Chem Biol. 2013; 8(6):1121-7.
Score: 0.024