"Carcinoma, Merkel Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)
| Descriptor ID |
D015266
|
| MeSH Number(s) |
C02.256.721.150 C02.928.216 C04.557.465.625.650.240.325 C04.557.470.200.025.370.325 C04.557.580.625.650.240.325
|
| Concept/Terms |
Carcinoma, Merkel Cell- Carcinoma, Merkel Cell
- Merkle Tumors
- Tumors, Merkle
- Merkel Cell Tumor
- Tumor, Merkel Cell
- Merkel Cell Cancer
- Cancer, Merkel Cell
- Cell Cancer, Merkel
- Merkel Cell Carcinoma
|
Below are MeSH descriptors whose meaning is more general than "Carcinoma, Merkel Cell".
- Diseases [C]
- Virus Diseases [C02]
- DNA Virus Infections [C02.256]
- Polyomavirus Infections [C02.256.721]
- Carcinoma, Merkel Cell [C02.256.721.150]
- Tumor Virus Infections [C02.928]
- Carcinoma, Merkel Cell [C02.928.216]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Neoplasms, Germ Cell and Embryonal [C04.557.465]
- Neuroectodermal Tumors [C04.557.465.625]
- Neuroendocrine Tumors [C04.557.465.625.650]
- Carcinoma, Neuroendocrine [C04.557.465.625.650.240]
- Carcinoma, Merkel Cell [C04.557.465.625.650.240.325]
- Neoplasms, Glandular and Epithelial [C04.557.470]
- Carcinoma [C04.557.470.200]
- Adenocarcinoma [C04.557.470.200.025]
- Carcinoma, Neuroendocrine [C04.557.470.200.025.370]
- Carcinoma, Merkel Cell [C04.557.470.200.025.370.325]
- Neoplasms, Nerve Tissue [C04.557.580]
- Neuroectodermal Tumors [C04.557.580.625]
- Neuroendocrine Tumors [C04.557.580.625.650]
- Carcinoma, Neuroendocrine [C04.557.580.625.650.240]
- Carcinoma, Merkel Cell [C04.557.580.625.650.240.325]
Below are MeSH descriptors whose meaning is more specific than "Carcinoma, Merkel Cell".
This graph shows the total number of publications written about "Carcinoma, Merkel Cell" by people in this website by year, and whether "Carcinoma, Merkel Cell" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Carcinoma, Merkel Cell" by people in Profiles.
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Karpinski P, Mendez-Pena JE, Wu CL, Akalin A, Cornejo KM, Hung YP, Hoang MP. POU4F3 Is a Sensitive and Specific Marker of Merkel Cell Carcinoma. Mod Pathol. 2025 Jan; 38(1):100627.
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Muralidharan S, Kervarrec T, Weiss GJ, Samimi M. Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel cell carcinoma. Oncotarget. 2022; 13:960-967.
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Ahmadi Moghaddam P, Cornejo KM, Hutchinson L, Tomaszewicz K, Dresser K, Deng A, O'Donnell P. Complete Spontaneous Regression of Merkel Cell Carcinoma After Biopsy: A Case Report and Review of the Literature. Am J Dermatopathol. 2016 Nov; 38(11):e154-e158.
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Tseng J, Dhungel B, Mills JK, Diggs BS, Weerasinghe R, Fortino J, Vetto JT. Merkel cell carcinoma: what makes a difference? Am J Surg. 2015 Feb; 209(2):342-6.
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Marghalani S, Feller JK, Mahalingam M, Mirzabeigi M. Huntingtin interacting protein 1 as a histopathologic adjunct in the diagnosis of Merkel cell carcinoma. Int J Dermatol. 2015 Jun; 54(6):640-7.
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D'Agostino M, Cinelli C, Willard R, Hofmann J, Jellinek N, Robinson-Bostom L. Epidermotropic Merkel cell carcinoma: a case series with histopathologic examination. J Am Acad Dermatol. 2010 Mar; 62(3):463-8.
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Keeling AN, Johnson NP, Farrelly C, Mahajan A, Dill KE, Losordo DW, Malaisrie SC, Benson AB. Right atrial Merkel cell carcinoma metastasis. J Am Coll Cardiol. 2010 Feb 02; 55(5):496.
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Jessup TP, Wassef WY, Yantiss RK, Bhattacharya K. Metastatic Merkel cell carcinoma diagnosed by EUS-guided FNA of a rapidly progressive peripancreatic mass. Gastrointest Endosc. 2006 Mar; 63(3):527-9.
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Lischko AM, Seddon JM, Gragoudas ES, Egan KM, Glynn RJ. Evaluation of prior primary malignancy as a determinant of uveal melanoma. A case-control study. Ophthalmology. 1989 Dec; 96(12):1716-21.