Glutaryl-CoA Dehydrogenase
"Glutaryl-CoA Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein enzyme that is responsible for the catabolism of LYSINE; HYDROXYLYSINE; and TRYPTOPHAN. It catalyzes the oxidation of GLUTARYL-CoA to crotonoyl-CoA using FAD as a cofactor. Glutaric aciduria type I is an inborn error of metabolism due to the deficiency of glutaryl-CoA dehydrogenase.
| Descriptor ID |
D050770
|
| MeSH Number(s) |
D08.811.682.660.425
|
| Concept/Terms |
Glutaryl-CoA Dehydrogenase- Glutaryl-CoA Dehydrogenase
- Dehydrogenase, Glutaryl-CoA
- Glutaryl-Coenzyme A Dehydrogenase
- Dehydrogenase, Glutaryl-Coenzyme A
- Glutaryl Coenzyme A Dehydrogenase
- Glutaryl CoA Dehydrogenase
- CoA Dehydrogenase, Glutaryl
- Dehydrogenase, Glutaryl CoA
|
Below are MeSH descriptors whose meaning is more general than "Glutaryl-CoA Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Glutaryl-CoA Dehydrogenase".
This graph shows the total number of publications written about "Glutaryl-CoA Dehydrogenase" by people in this website by year, and whether "Glutaryl-CoA Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glutaryl-CoA Dehydrogenase" by people in Profiles.
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Strauss KA, Williams KB, Carson VJ, Poskitt L, Bowser LE, Young M, Robinson DL, Hendrickson C, Beiler K, Taylor CM, Haas-Givler B, Hailey J, Chopko S, Puffenberger EG, Brigatti KW, Miller F, Morton DH. Glutaric acidemia type 1: Treatment and outcome of 168 patients over three decades. Mol Genet Metab. 2020 11; 131(3):325-340.
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Strauss KA, Brumbaugh J, Duffy A, Wardley B, Robinson D, Hendrickson C, Tortorelli S, Moser AB, Puffenberger EG, Rider NL, Morton DH. Safety, efficacy and physiological actions of a lysine-free, arginine-rich formula to treat glutaryl-CoA dehydrogenase deficiency: focus on cerebral amino acid influx. Mol Genet Metab. 2011 Sep-Oct; 104(1-2):93-106.
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Strauss KA, Donnelly P, Wintermark M. Cerebral haemodynamics in patients with glutaryl-coenzyme A dehydrogenase deficiency. Brain. 2010 Jan; 133(Pt 1):76-92.
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Strauss KA, Lazovic J, Wintermark M, Morton DH. Multimodal imaging of striatal degeneration in Amish patients with glutaryl-CoA dehydrogenase deficiency. Brain. 2007 Jul; 130(Pt 7):1905-20.
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Strauss KA, Morton DH. Type I glutaric aciduria, part 2: a model of acute striatal necrosis. Am J Med Genet C Semin Med Genet. 2003 Aug 15; 121C(1):53-70.
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Strauss KA, Puffenberger EG, Robinson DL, Morton DH. Type I glutaric aciduria, part 1: natural history of 77 patients. Am J Med Genet C Semin Med Genet. 2003 Aug 15; 121C(1):38-52.