Retinopathy of Prematurity

"Retinopathy of Prematurity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Descriptor ID	D012178
MeSH Number(s)	C11.768.836 C16.614.521.731
Concept/Terms	Retinopathy of Prematurity Retinopathy of Prematurity Prematurity Retinopathies Prematurity Retinopathy Retrolental Fibroplasia Fibroplasia, Retrolental Fibroplasias, Retrolental Retrolental Fibroplasias

Below are MeSH descriptors whose meaning is more general than "Retinopathy of Prematurity".

Diseases [C]
Eye Diseases [C11]
Retinal Diseases [C11.768]
Retinopathy of Prematurity [C11.768.836]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Infant, Newborn, Diseases [C16.614]
Infant, Premature, Diseases [C16.614.521]
Retinopathy of Prematurity [C16.614.521.731]

Below are MeSH descriptors whose meaning is more specific than "Retinopathy of Prematurity".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Retinopathy of Prematurity" by people in this website by year, and whether "Retinopathy of Prematurity" was a major or minor topic of these publications.

Bar chart showing 12 publications over 11 distinct years, with a maximum of 2 publications in 2025

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	1	0	1
2001	1	0	1
2003	0	1	1
2009	1	0	1
2010	1	0	1
2011	0	1	1
2018	1	0	1
2019	1	0	1
2021	1	0	1
2022	1	0	1
2025	1	1	2

Below are the most recent publications written about "Retinopathy of Prematurity" by people in Profiles.

Sriram S, Jensen ET, Msall ME, Yi JX, Zhabotynski V, Joseph RM, Kuban KCK, Frazier JA, Hooper SR, Santos HP, Gogcu S, Dammann C, Dammann O, Shenberger J, Fry RC, O'Shea TM. Retinopathy of Prematurity and Neurodevelopmental and Quality-of-Life Outcomes at 10 Years of Age. Am J Perinatol. 2026 Apr; 43(5):691-706.

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Vaidya R, Yi JX, O'Shea TM, Jensen ET, Joseph RM, Shenberger JS, Makker K, Yanni D, Frazier JA, Fry R, Msall M, Gogcu S, Singh R. Count of Neonatal Morbidities Predicts Outcomes at Age 10 and 15 Years in Infants Born Extremely Preterm. J Pediatr. 2025 Oct; 285:114709.

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Jastrzembski BG, VanderVeen D, Oke I. Social Conditions and the Rate of Severe Retinopathy of Prematurity Among a Diverse Cohort of Infants. JAMA Ophthalmol. 2023 01 01; 141(1):104.

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Vaidya R, Zitnik E, Kita T, Wagner K, Marie PS, Visintainer P, Singh R. Utilizing near infra-red spectroscopy to identify physiologic variations during digital retinal imaging in preterm infants. J Perinatol. 2022 Mar; 42(3):378-384.

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Mantagos IS, Wu C, Griffith JF, Jastrzembski BG, Gonzalez E, Goldstein S, Pearlo L, Vanderveen DK. Retinopathy of prematurity screening and risk mitigation during the COVID-19 pandemic. J AAPOS. 2021 04; 25(2):91.e1-91.e5.

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Torr C, Yoder B, Beachy J. Improving preoperative identification of infants at risk for severe retinopathy of prematurity. J Perinatol. 2019 09; 39(9):1309-1314.

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Torr C, Yoder B, Beachy J. Assessing the Surgical Experience to Identify Risk Factors Associated with Severe Retinopathy of Prematurity and Laser Intervention. Neonatology. 2018; 114(3):230-234.

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Fang L, Barber AJ, Shenberger JS. Regulation of fibroblast growth factor 2 expression in oxygen-induced retinopathy. Invest Ophthalmol Vis Sci. 2014 Dec 18; 56(1):207-15.

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Allred EN, Capone A, Fraioli A, Dammann O, Droste P, Duker J, Gise R, Kuban K, Leviton A, O'Shea TM, Paneth N, Petersen R, Trese M, Stoessel K, Vanderveen D, Wallace DK, Weaver G. Retinopathy of prematurity and brain damage in the very preterm newborn. J AAPOS. 2014 Jun; 18(3):241-7.

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Berkowitz BA, Bissig D, Bergman D, Bercea E, Kasturi VK, Roberts R. Intraretinal calcium channels and retinal morbidity in experimental retinopathy of prematurity. Mol Vis. 2011; 17:2516-26.

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