N-Formylmethionine Leucyl-Phenylalanine

"N-Formylmethionine Leucyl-Phenylalanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated.

Descriptor ID	D009240
MeSH Number(s)	D02.886.030.676.450.440 D12.125.072.050.685.445 D12.125.142.666.500 D12.125.166.676.450.440 D12.644.456.400 D23.125.685
Concept/Terms	N-Formylmethionine Leucyl-Phenylalanine N-Formylmethionine Leucyl-Phenylalanine Leucyl-Phenylalanine, N-Formylmethionine N Formylmethionine Leucyl Phenylalanine Formylmethionyl-Leucyl-Phenylalanine Formylmethionyl Leucyl Phenylalanine N-Formyl-Methionyl-Leucyl-Phenylalanine N Formyl Methionyl Leucyl Phenylalanine Formylmet-Leu-Phe Formylmet Leu Phe Formylmethionylleucylphenylalanine N-formylmethionyl-leucyl-phenylalanine N-formylmethionyl-leucyl-phenylalanine N formylmethionyl leucyl phenylalanine Formylmethionyl Peptide Formylmethionyl Peptide Peptide, Formylmethionyl N-Formylated Peptide N Formylated Peptide Peptide, N-Formylated F-Met-Leu-Phe F-Met-Leu-Phe F Met Leu Phe fMet-Leu-Phe fMet Leu Phe

Below are MeSH descriptors whose meaning is more general than "N-Formylmethionine Leucyl-Phenylalanine".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Sulfur Compounds [D02.886]
Amino Acids, Sulfur [D02.886.030]
Methionine [D02.886.030.676]
N-Formylmethionine [D02.886.030.676.450]
N-Formylmethionine Leucyl-Phenylalanine [D02.886.030.676.450.440]
Amino Acids, Peptides, and Proteins [D12]
Amino Acids [D12.125]
Amino Acids, Cyclic [D12.125.072]
Amino Acids, Aromatic [D12.125.072.050]
Phenylalanine [D12.125.072.050.685]
N-Formylmethionine Leucyl-Phenylalanine [D12.125.072.050.685.445]
Amino Acids, Essential [D12.125.142]
Phenylalanine [D12.125.142.666]
N-Formylmethionine Leucyl-Phenylalanine [D12.125.142.666.500]
Amino Acids, Sulfur [D12.125.166]
Methionine [D12.125.166.676]
N-Formylmethionine [D12.125.166.676.450]
N-Formylmethionine Leucyl-Phenylalanine [D12.125.166.676.450.440]
Peptides [D12.644]
Oligopeptides [D12.644.456]
N-Formylmethionine Leucyl-Phenylalanine [D12.644.456.400]
Biological Factors [D23]
Chemotactic Factors [D23.125]
N-Formylmethionine Leucyl-Phenylalanine [D23.125.685]

Below are MeSH descriptors whose meaning is related to "N-Formylmethionine Leucyl-Phenylalanine".

Below are MeSH descriptors whose meaning is more specific than "N-Formylmethionine Leucyl-Phenylalanine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "N-Formylmethionine Leucyl-Phenylalanine" by people in this website by year, and whether "N-Formylmethionine Leucyl-Phenylalanine" was a major or minor topic of these publications.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 1996 and 1998 and 1999 and 2003 and 2014

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1996	1	1
1998	1	1
1999	1	1
2003	1	1
2014	1	1

Below are the most recent publications written about "N-Formylmethionine Leucyl-Phenylalanine" by people in Profiles.

Taylor A, Tang W, Bruscia EM, Zhang PX, Lin A, Gaines P, Wu D, Halene S. SRF is required for neutrophil migration in response to inflammation. Blood. 2014 May 08; 123(19):3027-36.

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Zhang X, Kluger Y, Nakayama Y, Poddar R, Whitney C, DeTora A, Weissman SM, Newburger PE. Gene expression in mature neutrophils: early responses to inflammatory stimuli. J Leukoc Biol. 2004 Feb; 75(2):358-72.

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McCormick BA, Fernandez MI, Siber AM, Maurelli AT. Inhibition of Shigella flexneri-induced transepithelial migration of polymorphonuclear leucocytes by cadaverine. Cell Microbiol. 1999 Sep; 1(2):143-55.

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Shaw SK, Hermanowski-Vosatka A, Shibahara T, McCormick BA, Parkos CA, Carlson SL, Ebert EC, Brenner MB, Madara JL. Migration of intestinal intraepithelial lymphocytes into a polarized epithelial monolayer. Am J Physiol. 1998 09; 275(3):G584-91.

View in: PubMed
DiGiovine B, Lynch JP, Martinez FJ, Flint A, Whyte RI, Iannettoni MD, Arenberg DA, Burdick MD, Glass MC, Wilke CA, Morris SB, Kunkel SL, Strieter RM. Bronchoalveolar lavage neutrophilia is associated with obliterative bronchiolitis after lung transplantation: role of IL-8. J Immunol. 1996 Nov 01; 157(9):4194-202.

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Bernardo J, Brennan L, Brink HF, Ortiz MF, Newburger PE, Simons ER. Chemotactic peptide-induced cytoplasmic pH changes in incubated human monocytes. J Leukoc Biol. 1993 Jun; 53(6):673-8.

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Lynn WA, Raetz CR, Qureshi N, Golenbock DT. Lipopolysaccharide-induced stimulation of CD11b/CD18 expression on neutrophils. Evidence of specific receptor-based response and inhibition by lipid A-based antagonists. J Immunol. 1991 Nov 01; 147(9):3072-9.

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Bernardo J, Newburger PE, Brennan L, Brink HF, Bresnick SA, Weil G, Simons ER. Simultaneous flow cytometric measurements of cytoplasmic Ca++ and membrane potential changes upon FMLP exposure as HL-60 cells mature into granulocytes: using [Ca++]in as an indicator of granulocyte maturity. J Leukoc Biol. 1990 Mar; 47(3):265-74.

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Simpkins CO, Mazorow DL, Alailima ST, Tate EA, Sweatt W, Johnson M, Shariff K, Millar DB. Prostaglandin D2 modulates human neutrophil intracellular calcium flux and inhibits superoxide release via its ring carbonyl. Life Sci. 1990; 46(11):793-801.

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Tauber AI, Pavlotsky N, Lin JS, Rice PA. Inhibition of human neutrophil NADPH oxidase by Chlamydia serovars E, K, and L2. Infect Immun. 1989 Apr; 57(4):1108-12.

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