"Rotaxanes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Complex compounds in which a dumbbell shaped molecule is encircled by a macrocycle. They are named after rota (wheel) and axis (axle). Notation with a prefix is used to indicate the number of interlocked components. They have potential use in NANOTECHNOLOGY. Rotaxanes have been made with CYCLODEXTRINS and CYCLIC ETHERS.
| Descriptor ID |
D043862
|
| MeSH Number(s) |
D02.825
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Rotaxanes".
Below are MeSH descriptors whose meaning is more specific than "Rotaxanes".
This graph shows the total number of publications written about "Rotaxanes" by people in this website by year, and whether "Rotaxanes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Rotaxanes" by people in Profiles.
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Caldwell ST, Maclean C, Riehle M, Cooper A, Nutley M, Rabani G, Fitzpatrick B, Rotello VM, Smith BO, Khaled B, Woisel P, Cooke G. Protein-mediated dethreading of a biotin-functionalised pseudorotaxane. Org Biomol Chem. 2014 Jan 21; 12(3):511-6.
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Caldwell ST, Cooke G, Cooper A, Nutley M, Rabani G, Rotello V, Smith BO, Woisel P. Tuneable pseudorotaxane formation between a biotin-avidin bioconjugate and CBPQT4+. Chem Commun (Camb). 2008 Jun 21; (23):2650-2.
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Cooke G, Garety JF, Jordan B, Kryvokhyzha N, Parkin A, Rabani G, Rotello VM. Flavin-based [2]rotaxanes. Org Lett. 2006 May 25; 8(11):2297-300.