"Selegiline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.
| Descriptor ID |
D012642
|
| MeSH Number(s) |
D02.092.471.683.915
|
| Concept/Terms |
Selegiline- Selegiline
- Selegiline, (R)-Isomer
- Selegyline
- L-Deprenyl
|
Below are MeSH descriptors whose meaning is more general than "Selegiline".
Below are MeSH descriptors whose meaning is more specific than "Selegiline".
This graph shows the total number of publications written about "Selegiline" by people in this website by year, and whether "Selegiline" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Selegiline" by people in Profiles.
-
Ishikawa T, Okano M, Minami A, Tsunekawa H, Satoyoshi H, Tsukamoto Y, Takahata K, Muraoka S. Selegiline ameliorates depression-like behaviors in rodents and modulates hippocampal dopaminergic transmission and synaptic plasticity. Behav Brain Res. 2019 02 01; 359:353-361.
-
Takahata K, Minami A, Kusumoto H, Shimazu S, Yoneda F. Effects of selegiline alone or with donepezil on memory impairment in rats. Eur J Pharmacol. 2005 Aug 22; 518(2-3):140-4.
-
Shimazu S, Minami A, Kusumoto H, Yoneda F. Antidepressant-like effects of selegiline in the forced swim test. Eur Neuropsychopharmacol. 2005 Oct; 15(5):563-71.