"Ethacrynic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
| Descriptor ID |
D004976
|
| MeSH Number(s) |
D02.241.081.018.386.682.300 D02.241.511.316.682.200
|
| Concept/Terms |
Ethacrynic Acid- Ethacrynic Acid
- Acid, Ethacrynic
- Etacrynic Acid
- Acid, Etacrynic
- Ethacrinic Acid
- Acid, Ethacrinic
|
Below are MeSH descriptors whose meaning is more general than "Ethacrynic Acid".
Below are MeSH descriptors whose meaning is more specific than "Ethacrynic Acid".
This graph shows the total number of publications written about "Ethacrynic Acid" by people in this website by year, and whether "Ethacrynic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ethacrynic Acid" by people in Profiles.
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Huff MO, Li XP, Ginns E, El-Mallakh RS. Effect of ethacrynic acid on the sodium- and potassium-activated adenosine triphosphatase activity and expression in Old Order Amish bipolar individuals. J Affect Disord. 2010 Jun; 123(1-3):303-7.
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Trute M, Gallis B, Doneanu C, Shaffer S, Goodlett D, Gallagher E. Characterization of hepatic glutathione S-transferases in coho salmon (Oncorhynchus kisutch). Aquat Toxicol. 2007 Feb 28; 81(2):126-36.
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Park CS, Doh PS, Lee CJ, Han DS, Carraway RE, Miller TB. Cellular mechanism of stimulation of renin secretion by the mercurial diuretic mersalyl. J Pharmacol Exp Ther. 1991 Apr; 257(1):219-24.
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Park CS, Doh PS, Carraway RE, Chung GG, Fray JC, Miller TB. Stimulation of renin secretion by ethacrynic acid is independent of Na(+)-K(+)-2Cl- cotransport. Am J Physiol. 1990 Oct; 259(4 Pt 2):F539-44.