Brain Death

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"Brain Death" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)

Descriptor ID	D001926
MeSH Number(s)	C10.228.140.151 C10.597.606.358.800.200.100 C23.550.260.159
Concept/Terms	Brain Death Brain Death Death, Brain Brain Dead Brain Deads Coma Depasse Irreversible Coma Irreversible Coma Coma, Irreversible

Below are MeSH descriptors whose meaning is more general than "Brain Death".

Diseases [C]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Brain Death [C10.228.140.151]
Neurologic Manifestations [C10.597]
Neurobehavioral Manifestations [C10.597.606]
Consciousness Disorders [C10.597.606.358]
Unconsciousness [C10.597.606.358.800]
Coma [C10.597.606.358.800.200]
Brain Death [C10.597.606.358.800.200.100]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Death [C23.550.260]
Brain Death [C23.550.260.159]

Below are MeSH descriptors whose meaning is related to "Brain Death".

Below are MeSH descriptors whose meaning is more specific than "Brain Death".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Brain Death" by people in this website by year, and whether "Brain Death" was a major or minor topic of these publications.

Bar chart showing 11 publications over 10 distinct years, with a maximum of 2 publications in 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
2004	1	0	1
2008	1	0	1
2011	1	0	1
2012	1	0	1
2014	1	0	1
2015	1	0	1
2016	0	1	1
2021	1	0	1
2022	1	1	2

Below are the most recent publications written about "Brain Death" by people in Profiles.

Lerner DP, Tadevosyan A, Scott BJ, Ramineni A, Bassil R, Burns JD, Russell JA. Single institution experience with death by neurological criteria/brain death guideline adherence. J Clin Neurosci. 2023 Feb; 108:25-29.

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Mikami T, Itagaki S, Fujisaki T, Kuno T, Lerner DP, Burns JD, Anyanwu AC. Association of Donor Brain Death Due to Stroke With Prognosis After Heart Transplantation. J Am Coll Cardiol. 2022 03 22; 79(11):1063-1072.

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Lei B, Sleiman MM, Cheng Q, Tu Z, Zhu P, Goddard M, Martins PN, Langerude L, Nadig S, Tomlinson S, Atkinson C. In Situ Pre-Treatment of Vascularized Composite Allografts With a Targeted Complement Inhibitor Protects Against Brain Death and Ischemia Reperfusion Induced Injuries. Front Immunol. 2021; 12:630581.

View in: PubMed
Lerner DP, Bassil R, Tadevosyan A, Ramineni A, Burns JD, Russell JA, Varelas PN, Lewis A. Metabolic values precluding clinical death by neurologic Criteria/Brain death: Survey of neurocritical care society physicians. J Clin Neurosci. 2021 Jun; 88:16-21.

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Cheng Q, Patel K, Lei B, Rucker L, Allen DP, Zhu P, Vasu C, Martins PN, Goddard M, Nadig SN, Atkinson C. Donor pretreatment with nebulized complement C3a receptor antagonist mitigates brain-death induced immunological injury post-lung transplant. Am J Transplant. 2018 10; 18(10):2417-2428.

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Neavyn MJ, Stolbach A, Greer DM, Nelson LS, Smith SW, Brent J, Tormoehlen LM. ACMT Position Statement: Determining Brain Death in Adults After Drug Overdose. J Med Toxicol. 2017 09; 13(3):271-273.

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Murray MJ, DeBlock H, Erstad B, Gray A, Jacobi J, Jordan C, McGee W, McManus C, Meade M, Nix S, Patterson A, Sands MK, Pino R, Tescher A, Arbour R, Rochwerg B, Murray CF, Mehta S. Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critically Ill Patient. Crit Care Med. 2016 Nov; 44(11):2079-2103.

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Ahlawat A, Carandang R, Heard SO, Muehlschlegel S. The Modified Apnea Test During Brain Death Determination: An Alternative in Patients With Hypoxia. J Intensive Care Med. 2016 Jan; 31(1):66-9.

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Thompson BB, Wendell LC, Potter NS, Fehnel C, Wilterdink J, Silver B, Furie K. The use of transcranial Doppler ultrasound in confirming brain death in the setting of skull defects and extraventricular drains. Neurocrit Care. 2014 Dec; 21(3):534-8.

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Neavyn MJ. Suicide and the surrogate. J Med Toxicol. 2014 Mar; 10(1):3-6.

View in: PubMed

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