"Neurofibroma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
| Descriptor ID |
D009455
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| MeSH Number(s) |
C04.557.580.600.580 C10.551.775.500.750 C10.668.829.725.500.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neurofibroma".
Below are MeSH descriptors whose meaning is more specific than "Neurofibroma".
This graph shows the total number of publications written about "Neurofibroma" by people in this website by year, and whether "Neurofibroma" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Neurofibroma" by people in Profiles.
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Jokinen CH, Dadras SS, Goldblum JR, van de Rijn M, West RB, Rubin BP. Diagnostic implications of podoplanin expression in peripheral nerve sheath neoplasms. Am J Clin Pathol. 2008 Jun; 129(6):886-93.
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Sukumar S, Armstrong B, Bruyntjes JP, Leav I, Bosland MC. Frequent activation of the Ki-ras oncogene at codon 12 in N-methyl-N-nitrosourea-induced rat prostate adenocarcinomas and neurogenic sarcomas. Mol Carcinog. 1991; 4(5):362-8.
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Kransdorf MJ, Jelinek JS, Moser RP, Utz JA, Brower AC, Hudson TM, Berrey BH. Soft-tissue masses: diagnosis using MR imaging. AJR Am J Roentgenol. 1989 Sep; 153(3):541-7.