Methylphenidate

"Methylphenidate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.

Descriptor ID	D008774
MeSH Number(s)	D02.241.223.601.600 D03.383.621.460
Concept/Terms	Methylphenidate Methylphenidate Metadate Metadate Equasym Methylin Methylin Concerta Concerta Phenidylate Phenidylate Ritalin Ritalin Ritaline Ritalin-SR Ritalin-SR Ritalin SR Tsentedrin Tsentedrin Centedrin Daytrana Daytrana Methylphenidate Hydrochloride Methylphenidate Hydrochloride Hydrochloride, Methylphenidate

Below are MeSH descriptors whose meaning is more general than "Methylphenidate".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Carboxylic Acids [D02.241]
Acids, Carbocyclic [D02.241.223]
Phenylacetates [D02.241.223.601]
Methylphenidate [D02.241.223.601.600]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Piperidines [D03.383.621]
Methylphenidate [D03.383.621.460]

Below are MeSH descriptors whose meaning is more specific than "Methylphenidate".

Methylphenidate
Dexmethylphenidate Hydrochloride

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Methylphenidate" by people in this website by year, and whether "Methylphenidate" was a major or minor topic of these publications.

Bar chart showing 16 publications over 11 distinct years, with a maximum of 4 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2004	1	0	1
2005	1	0	1
2006	1	0	1
2008	3	1	4
2009	1	0	1
2010	2	0	2
2012	2	0	2
2013	1	0	1
2018	1	0	1
2019	1	0	1

Below are the most recent publications written about "Methylphenidate" by people in Profiles.

Mazhar H, Foster BC, Necyk C, Gardiner PM, Harris CS, Robaey P. Natural Health Product-Drug Interaction Causality Assessment in Pediatric Adverse Event Reports Associated with Attention-Deficit/Hyperactivity Disorder Medication. J Child Adolesc Psychopharmacol. 2020 02; 30(1):38-47.

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Demiral SB, Tomasi D, Wiers CE, Manza P, Shokri-Kojori E, Studentsova Y, Wang GJ, Volkow ND. Methylphenidate's effects on thalamic metabolism and functional connectivity in cannabis abusers and healthy controls. Neuropsychopharmacology. 2019 07; 44(8):1389-1397.

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Feldman HM, Reiff MI. Clinical practice. Attention deficit-hyperactivity disorder in children and adolescents. N Engl J Med. 2014 Feb 27; 370(9):838-46.

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Czerniak SM, Sikoglu EM, King JA, Kennedy DN, Mick E, Frazier J, Moore CM. Areas of the brain modulated by single-dose methylphenidate treatment in youth with ADHD during task-based fMRI: a systematic review. Harv Rev Psychiatry. 2013 May-Jun; 21(3):151-62.

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Sheldrick RC, Leslie LK, Rodday AM, Parsons SK, Saunders TS, Wong JB. Variations in Physician Attitudes Regarding ADHD and Their Association With Prescribing Practices. J Atten Disord. 2015 Jul; 19(7):569-77.

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Daly B, Kral MC, Brown RT, Elkin D, Madan-Swain A, Mitchell M, Crosby L, Dematteo D, Larosa A, Jackson S. Ameliorating attention problems in children with sickle cell disease: a pilot study of methylphenidate. J Dev Behav Pediatr. 2012 Apr; 33(3):244-51.

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Hammerness P, Biederman J, Petty C, Henin A, Moore CM. Brain biochemical effects of methylphenidate treatment using proton magnetic spectroscopy in youth with attention-deficit hyperactivity disorder: a controlled pilot study. CNS Neurosci Ther. 2012 Jan; 18(1):34-40.

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Mick E, McGough JJ, Middleton FA, Neale B, Faraone SV. Genome-wide association study of blood pressure response to methylphenidate treatment of attention-deficit/hyperactivity disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Mar 30; 35(2):466-72.

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Biederman J, Mick E, Surman C, Doyle R, Hammerness P, Kotarski M, Spencer T. A randomized, 3-phase, 34-week, double-blind, long-term efficacy study of osmotic-release oral system-methylphenidate in adults with attention-deficit/hyperactivity disorder. J Clin Psychopharmacol. 2010 Oct; 30(5):549-53.

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Hammerness P, Wilens T, Mick E, Spencer T, Doyle R, McCreary M, Becker J, Biederman J. Cardiovascular effects of longer-term, high-dose OROS methylphenidate in adolescents with attention deficit hyperactivity disorder. J Pediatr. 2009 Jul; 155(1):84-9, 89.e1.

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