Purpura, Thrombotic Thrombocytopenic
"Purpura, Thrombotic Thrombocytopenic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE.
| Descriptor ID |
D011697
|
| MeSH Number(s) |
C15.378.100.802.687.680 C15.378.140.855.925.750.680 C15.378.925.850 C23.550.414.950.687.680 C23.888.885.687.687.680
|
| Concept/Terms |
Purpura, Thrombotic Thrombocytopenic- Purpura, Thrombotic Thrombocytopenic
- Thrombocytopenic Purpura, Thrombotic
- Moschkowitz Disease
- Disease, Moschkowitz
- Thrombotic Thrombocytopenic Purpura
- Moschcowitz Disease
- Disease, Moschcowitz
- Purpura, Thrombotic Thrombopenic
- Thrombopenic Purpura, Thrombotic
- Thrombotic Thrombopenic Purpura
Congenital Thrombotic Thrombocytopenic Purpura- Congenital Thrombotic Thrombocytopenic Purpura
- Schulman-Upshaw Syndrome
- Schulman Upshaw Syndrome
- Syndrome, Schulman-Upshaw
- Upshaw-Schulman Syndrome
- Syndrome, Upshaw-Schulman
- Upshaw Schulman Syndrome
- Thrombotic Thrombocytopenic Purpura, Congenital
- Upshaw Factor, Deficiency of
- Microangiopathic Hemolytic Anemia, Congenital
- Thrombotic Microangiopathy, Familial
- Familial Thrombotic Microangiopathy
- Microangiopathy, Familial Thrombotic
|
Below are MeSH descriptors whose meaning is more general than "Purpura, Thrombotic Thrombocytopenic".
- Diseases [C]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Blood Coagulation Disorders [C15.378.100]
- Purpura [C15.378.100.802]
- Purpura, Thrombocytopenic [C15.378.100.802.687]
- Purpura, Thrombotic Thrombocytopenic [C15.378.100.802.687.680]
- Blood Platelet Disorders [C15.378.140]
- Thrombocytopenia [C15.378.140.855]
- Thrombotic Microangiopathies [C15.378.140.855.925]
- Purpura, Thrombocytopenic [C15.378.140.855.925.750]
- Purpura, Thrombotic Thrombocytopenic [C15.378.140.855.925.750.680]
- Thrombophilia [C15.378.925]
- Purpura, Thrombotic Thrombocytopenic [C15.378.925.850]
- Pathological Conditions, Signs and Symptoms [C23]
- Pathologic Processes [C23.550]
- Hemorrhage [C23.550.414]
- Purpura [C23.550.414.950]
- Purpura, Thrombocytopenic [C23.550.414.950.687]
- Purpura, Thrombotic Thrombocytopenic [C23.550.414.950.687.680]
- Signs and Symptoms [C23.888]
- Skin Manifestations [C23.888.885]
- Purpura [C23.888.885.687]
- Purpura, Thrombocytopenic [C23.888.885.687.687]
- Purpura, Thrombotic Thrombocytopenic [C23.888.885.687.687.680]
Below are MeSH descriptors whose meaning is more specific than "Purpura, Thrombotic Thrombocytopenic".
This graph shows the total number of publications written about "Purpura, Thrombotic Thrombocytopenic" by people in this website by year, and whether "Purpura, Thrombotic Thrombocytopenic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Purpura, Thrombotic Thrombocytopenic" by people in Profiles.
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Bendapudi PK, Foy BH, Mueller SB, Liu J, Feingold LM, Burke KE, Cruz W, Chen MY, Lau ES, Goldberg RL, Tatake I, Wilkinson SC, Carney BJ, Stone JR, Park D, Avelino AR, Hassan S, Andrzejewski C, Ruby KN, Friedman KD, Brunker PAR, Leaf RK, Higgins J, Dzik WH, Stefely JA, Makar RS. Recombinant ADAMTS13 for Immune Thrombotic Thrombocytopenic Purpura. N Engl J Med. 2024 May 09; 390(18):1690-1698.
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Nguyen SN, Le SH, Ivanov DG, Ivetic N, Nazy I, Kaltashov IA. Structural Characterization of a Pathogenic Antibody Underlying Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT). Anal Chem. 2024 04 23; 96(16):6209-6217.
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Albo Z, Mathew C, Catton R, Silver B, Moonis M. Thrombotic Thrombocytopenic Purpura (ADAMTS13 [a Disintegrin and Metalloproteinase With a Thrombospondin Type 1 Motif, Member 13] Deficiency) as Cause of Recurrent Multiterritory Ischemic Strokes. Stroke. 2022 06; 53(6):e237-e240.
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Salhab M, Hsu A, Ryer E, Appiah J, Switzer B. Microangiopathic hemolytic anemia in pregnancy. Transfus Apher Sci. 2017 Jun; 56(3):354-356.
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Abu-Hishmeh M, Sattar A, Zarlasht F, Ramadan M, Abdel-Rahman A, Hinson S, Hwang C. Systemic Lupus Erythematosus Presenting as Refractory Thrombotic Thrombocytopenic Purpura: A Diagnostic and Management Challenge. A Case Report and Concise Review of the Literature. Am J Case Rep. 2016 Oct 25; 17:782-787.
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Zenno A, Richardson M. Coombs Positive Thrombotic Thrombocytopenic Purpura in a Male Pediatric Patient: An Urgent Diagnostic Challenge. Pediatr Blood Cancer. 2016 10; 63(10):1860-2.
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Doldan-Silvero A, Acevedo-Gadea C, Habib C, Freeman J, Johari V. ADAMTS13 activity and inhibitor. Am J Hematol. 2008 Oct; 83(10):811-4.
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Schmugge M, Dunn MS, Amankwah KS, Blanchette VS, Freedman J, Rand ML. The activity of the von Willebrand factor cleaving protease ADAMTS-13 in newborn infants. J Thromb Haemost. 2004 Feb; 2(2):228-33.