2-Pyridinylmethylsulfinylbenzimidazoles
"2-Pyridinylmethylsulfinylbenzimidazoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS.
Descriptor ID |
D053799
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MeSH Number(s) |
D02.886.640.074 D03.383.725.024 D03.633.100.103.034
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Concept/Terms |
2-Pyridinylmethylsulfinylbenzimidazoles- 2-Pyridinylmethylsulfinylbenzimidazoles
- 2 Pyridinylmethylsulfinylbenzimidazoles
- Benzimidazole Methylpyridine Sulfoxides
- Methylpyridine Sulfoxides, Benzimidazole
- Sulfoxides, Benzimidazole Methylpyridine
Timoprazole Derivatives- Timoprazole Derivatives
- Timoprazoles
- 2-Methylpyridine 2-Benzimidazole Sulfoxides
- 2 Methylpyridine 2 Benzimidazole Sulfoxides
- 2-Benzimidazole Sulfoxides, 2-Methylpyridine
- Sulfoxides, 2-Methylpyridine 2-Benzimidazole
- 2-Pyridinylmethylsulfinyl-2-Benzimidazoles
- 2 Pyridinylmethylsulfinyl 2 Benzimidazoles
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Below are MeSH descriptors whose meaning is more general than "2-Pyridinylmethylsulfinylbenzimidazoles".
Below are MeSH descriptors whose meaning is more specific than "2-Pyridinylmethylsulfinylbenzimidazoles".
This graph shows the total number of publications written about "2-Pyridinylmethylsulfinylbenzimidazoles" by people in this website by year, and whether "2-Pyridinylmethylsulfinylbenzimidazoles" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "2-Pyridinylmethylsulfinylbenzimidazoles" by people in Profiles.
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Felton D, Zitomersky N, Manzi S, Lightdale JR. 13-year-old girl with recurrent, episodic, persistent vomiting: out of the pot and into the fire. Pediatrics. 2015 Apr; 135(4):e1060-3.
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Frelinger AL, Bhatt DL, Lee RD, Mulford DJ, Wu J, Nudurupati S, Nigam A, Lampa M, Brooks JK, Barnard MR, Michelson AD. Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in platelet function. J Am Coll Cardiol. 2013 Feb 26; 61(8):872-9.
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Frelinger AL, Lee RD, Mulford DJ, Wu J, Nudurupati S, Nigam A, Brooks JK, Bhatt DL, Michelson AD. A randomized, 2-period, crossover design study to assess the effects of dexlansoprazole, lansoprazole, esomeprazole, and omeprazole on the steady-state pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers. J Am Coll Cardiol. 2012 Apr 03; 59(14):1304-11.
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Mansour NM, Hashash JG, El-Halabi M, Ghaith O, Maasri K, Sukkarieh I, Malli A, Sharara AI. A randomized trial of standard-dose versus half-dose rabeprazole, clarithromycin, and amoxicillin in the treatment of Helicobacter pylori infection. Eur J Gastroenterol Hepatol. 2011 Oct; 23(10):865-70.
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Micalizzi M, Fraga P, Meng X. Comparative tolerability of 2- and 15-minute intravenous infusions of pantoprazole. Am J Health Syst Pharm. 2007 Sep 01; 64(17):1822-6.
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Bochenek WJ, Peters S, Fraga PD, Wang W, Mack ME, Osato MS, El-Zimaity HM, Davis KD, Graham DY. Eradication of Helicobacter pylori by 7-day triple-therapy regimens combining pantoprazole with clarithromycin, metronidazole, or amoxicillin in patients with peptic ulcer disease: results of two double-blind, randomized studies. Helicobacter. 2003 Dec; 8(6):626-42.